Deficient cotinine formation from nicotine is attributed to the whole deletion of the CYP2A6 gene in humans
about
Polymorphisms of CYP2A6 and its practical consequencesPrecision Medicine for Tobacco Dependence: Development and Validation of the Nicotine Metabolite RatioBiomonitoring of urinary cotinine concentrations associated with plasma levels of nicotine metabolites after daily cigarette smoking in a male Japanese population.Pharmacogenetic diagnostics of cytochrome P450 polymorphisms in clinical drug development and in drug treatment.New Insights into the Mechanisms of Action of Cotinine and its Distinctive Effects from Nicotine.Interindividual differences in nicotine metabolism and genetic polymorphisms of human CYP2A6.The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-AmericansClinical considerations in study designs that use cotinine as a biomarker.A review and assessment of potential sources of ethnic differences in drug responsiveness.Differences in drug pharmacokinetics between East Asians and Caucasians and the role of genetic polymorphisms.Overview of the pharmacogenomics of cigarette smoking.CYP2A6 polymorphisms: is there a role for pharmacogenomics in preventing coumarin-induced hepatotoxicity in lymphedema patients?Past and future applications of CYP450-genetic polymorphisms for biomonitoring of environmental toxicants.Applications of CYP-450 expression for biomonitoring in environmental healthGenetic determinants of CYP2A6 activity across racial/ethnic groups with different risks of lung cancer and effect on their smoking intensityDistribution of polymorphic variants of CYP2A6 and their involvement in nicotine addiction.Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolismIsoflavones inhibit nicotine C-oxidation catalyzed by human CYP2A6.CYP2A6*6, a novel polymorphism in cytochrome p450 2A6, has a single amino acid substitution (R128Q) that inactivates enzymatic activity.Effects of whole deletion of CYP2A6 on nicotine metabolism in humans.More potent inhibition of human CYP2A6 than mouse CYP2A5 enzyme activities by derivatives of phenylethylamine and benzaldehyde.Cotinine levels and self-reported smoking status in patients attending a bronchoscopy clinic.Novel human CYP2A6 alleles confound gene deletion analysis.Differences between Spaniards and Ecuadorians in CYP2A6 allele frequencies: comparison with other populations.Impact of CYP2A6 genotype on pretreatment smoking behaviour and nicotine levels from and usage of nicotine replacement therapy.Cytochrome p450 metabolism of betel quid-derived compounds: implications for the development of prevention strategies for oral and pharyngeal cancers.
P2860
Q28362536-3E3D8D72-9657-432E-9110-312B7D46976AQ33821233-57F2FA0F-6B6C-489E-9854-F2DEE097AE81Q34070307-2D03AD8B-D864-497A-A609-EA70F1A9A429Q34188511-2A9B292A-6B3F-4FF4-BDC3-0D217E053C41Q34426718-66286EA3-791D-419E-8507-99C5DE6CA67FQ35027945-751B0417-3606-4622-B61A-14537AFC0799Q35048184-1FAA48FA-CCB3-4B58-8A0D-C57337054027Q35207903-BE9E5601-4624-4E38-918B-32B475F3E894Q35217493-CCC2ED05-4A15-4209-93D5-D217D5F3F8F5Q35876954-C81D48E7-4863-40E4-B98E-ABB0A7838ADBQ36708951-0E0A0B91-44E6-4A1C-A1C3-10932A34BBF4Q36730627-78F089BC-542C-4920-AF28-76C3C3E411E5Q37000474-BDD373D0-9618-4CBA-BD6D-0902EA9431E8Q37232322-7D69CFDD-371F-4E9A-ADA9-2B2BD1023440Q37238137-BEEDBA0F-FC8D-42C1-B3FA-A71CCCA66318Q38683483-FA8516C8-0BCB-4C5C-AF55-EBA257E9494EQ42284318-18234195-54D7-4A14-8CAD-895BB976BD6FQ42491133-F26744CC-0244-4E4A-9A3F-7A084F2EA7D4Q43559545-E7E2C5BF-CC87-44CC-9A8F-6F04B85F58A8Q44002892-E39491D6-707F-40C0-9A95-EC385FDD0BACQ44440357-B94B825E-8B5C-4908-A258-AB6D612CB129Q44565762-4C7ECD1E-A924-48E0-AC64-05D5C7F74EBCQ44957920-07C0A451-8345-4D56-94F6-FD285B322B66Q46436451-18CFB0D9-EAA0-4586-B406-D987753CBDA0Q46886466-E942D2A8-8D63-4487-8D2A-16095D00DEBCQ51370536-592C8C12-77F7-4E30-ACA9-7ECD11536E73
P2860
Deficient cotinine formation from nicotine is attributed to the whole deletion of the CYP2A6 gene in humans
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Deficient cotinine formation f ...... n of the CYP2A6 gene in humans
@ast
Deficient cotinine formation f ...... n of the CYP2A6 gene in humans
@en
Deficient cotinine formation f ...... n of the CYP2A6 gene in humans
@nl
type
label
Deficient cotinine formation f ...... n of the CYP2A6 gene in humans
@ast
Deficient cotinine formation f ...... n of the CYP2A6 gene in humans
@en
Deficient cotinine formation f ...... n of the CYP2A6 gene in humans
@nl
prefLabel
Deficient cotinine formation f ...... n of the CYP2A6 gene in humans
@ast
Deficient cotinine formation f ...... n of the CYP2A6 gene in humans
@en
Deficient cotinine formation f ...... n of the CYP2A6 gene in humans
@nl
P2093
P356
P1476
Deficient cotinine formation f ...... n of the CYP2A6 gene in humans
@en
P2093
P356
10.1067/MCP.2000.103957
P407
P577
2000-01-01T00:00:00Z