Synthesis, characterization and preclinical formulation of a dual-action phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07) with potent anti-HIV and spermicidal activities
about
Importance of the alanine methyl ester side chain for the biological activity profile of dual-function phenyl phosphate derivatives of bromo-methoxy-zidovudinePreclinical evaluation of a dual-acting microbicidal prodrug WHI-07 in combination with vanadocene dithiocarbamate in the female reproductive tract of rabbit, pig, and cat.Sophorolipids, microbial glycolipids with anti-human immunodeficiency virus and sperm-immobilizing activitiesSpermicidal and contraceptive potential of desgalactotigonin: a prospective alternative of nonoxynol-9.Considerations and development of topical microbicides to inhibit the sexual transmission of HIV.Evaluation of safety margins of Chenopodium album seed decoction: 14-day subacute toxicity and microbicidal activity studiesMicrobicidal spermicide or spermicidal microbicide?Antiretroviral spermicide WHI-07 prevents vaginal and rectal transmission of feline immunodeficiency virus in domestic cats.Update on nonoxynol-9 as vaginal spermicide.GM-144, a novel lipophilic vaginal contraceptive gel-microemulsionInfluence of long-term stability conditions on microbicidal nucleoside prodrug (WHI-07)-loaded gel-microemulsion.Lack of adverse effects on fertility of female CD-1 mice exposed to repetitive intravaginal gel-microemulsion formulation of a dual-function anti-HIV agent: aryl phosphate derivative of bromo-methoxy-zidovudine (compound WHI-07).A 13-week subchronic intravaginal toxicity study of the novel broad-spectrum anti-HIV and spermicidal agent, N-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea (PHI-346) in mice.Developmental toxicology studies of WHI-07, a novel nucleoside analogue-based dual-function microbicide, administered intravaginally to rabbits.Mucosal toxicity studies of a gel formulation of native pokeweed antiviral protein.Evaluation of subchronic (13-week) and reproductive toxicity potential of intravaginal gel-microemulsion formulation of a dual-function phenyl phosphate derivative of bromo-methoxy zidovudine (compound whi-07) in B(6)C(3)F(1) mice.
P2860
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P2860
Synthesis, characterization and preclinical formulation of a dual-action phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07) with potent anti-HIV and spermicidal activities
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Synthesis, characterization an ...... HIV and spermicidal activities
@ast
Synthesis, characterization an ...... HIV and spermicidal activities
@en
Synthesis, characterization an ...... HIV and spermicidal activities
@nl
type
label
Synthesis, characterization an ...... HIV and spermicidal activities
@ast
Synthesis, characterization an ...... HIV and spermicidal activities
@en
Synthesis, characterization an ...... HIV and spermicidal activities
@nl
prefLabel
Synthesis, characterization an ...... HIV and spermicidal activities
@ast
Synthesis, characterization an ...... HIV and spermicidal activities
@en
Synthesis, characterization an ...... HIV and spermicidal activities
@nl
P2093
P356
P1476
Synthesis, characterization an ...... HIV and spermicidal activities
@en
P2093
P304
P356
10.1093/MOLEHR/5.5.421
P407
P577
1999-05-01T00:00:00Z