Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base
about
Synthesis of nucleoside phosphate and phosphonate prodrugsVaccinia virus inhibitors as a paradigm for the chemotherapy of poxvirus infectionsAntiviral activities of novel 5-phosphono-pent-2-en-1-yl nucleosides and their alkoxyalkyl phosphonoestersAdenine: an important drug scaffold for the design of antiviral agents5-azacytosine compounds in medicinal chemistry: current stage and future perspectives.Medicinal chemistry of fluorinated cyclic and acyclic nucleoside phosphonates.Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis.Antiretrovirus activity of a novel class of acyclic pyrimidine nucleoside phosphonatesAcyclic nucleoside bisphosphonates: synthesis and properties of chiral 2-amino-4,6-bis[(phosphonomethoxy)alkoxy]pyrimidinesInhibition of herpesvirus replication by hexadecyloxypropyl esters of purine- and pyrimidine-based phosphonomethoxyethyl nucleoside phosphonates.Synthesis of acyclic nucleoside phosphonates.Phosphonylated Acyclic Guanosine Analogues with the 1,2,3-Triazole Linker.Synthesis of unsaturated carboacyclic nucleoside analogues via Mitsunobu reactions.Synthesis of 9-[1-(substituted)-3-(phosphonomethoxy)propyl]adenine derivatives as possible antiviral agents.Synthesis of beta-hydroxyphosphonate and 1,2-dihydroxy acyclic nucleoside analogs via 1,3-dipolar cycloaddition strategy.Formation of ternary complexes by coordination of (diethylenetriamine)-platinum(II) to N1 or N7 of the adenine moiety of the antiviral nucleotide analogue 9.Acyclic nucleoside/nucleotide analogues with an imidazole ring skeleton.Synthesis and acid-base properties of (1H-benzimidazol-2-yl-methyl)phosphonate (Bimp2-). Evidence for intramolecular hydrogen-bond formation in aqueous solution between (N-1)H and the phosphonate group.Interactions of trimeric purine nucleoside phosphorylases with ground state analogues--calorimetric and fluorimetric studies.Kinetics of binding of multisubstrate analogue inhibitor (2-amino-9-[2-(phosphonomethoxy)ethyl]-6-sulfanylpurine) with trimeric purine nucleoside phosphorylase.Pyrrolo[2,3-d]pyrimidine (7-deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides.Facile and Convenient Synthesis of Pyrazole, Pyridine, Pyridazine, Pyrazolo[3,4-b]pyridine, and Pyrazolo[5,1-c][1,2,4]triazine Derivatives
P2860
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P2860
Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Structure-antiviral activity r ...... t the carbon atoms of the base
@ast
Structure-antiviral activity r ...... t the carbon atoms of the base
@en
Structure-antiviral activity r ...... t the carbon atoms of the base
@nl
type
label
Structure-antiviral activity r ...... t the carbon atoms of the base
@ast
Structure-antiviral activity r ...... t the carbon atoms of the base
@en
Structure-antiviral activity r ...... t the carbon atoms of the base
@nl
prefLabel
Structure-antiviral activity r ...... t the carbon atoms of the base
@ast
Structure-antiviral activity r ...... t the carbon atoms of the base
@en
Structure-antiviral activity r ...... t the carbon atoms of the base
@nl
P2093
P50
P356
P1476
Structure-antiviral activity r ...... t the carbon atoms of the base
@en
P2093
H Dvoráková
M Masojídková
P304
P356
10.1021/JM9811256
P407
P577
1999-06-17T00:00:00Z