Retinoid-induced apoptosis and Sp1 cleavage occur independently of transcription and require caspase activation
about
Caspase-mediated cleavage of eukaryotic translation initiation factor subunit 2alphaTranscription factor AP-2alpha is preferentially cleaved by caspase 6 and degraded by proteasome during tumor necrosis factor alpha-induced apoptosis in breast cancer cellsGlutamate receptor activation evokes calpain-mediated degradation of Sp3 and Sp4, the prominent Sp-family transcription factors in neuronsAntagonists of retinoic acid receptors (RARs) are potent growth inhibitors of prostate carcinoma cellsTargeting of the transcription factor Max during apoptosis: phosphorylation-regulated cleavage by caspase-5 at an unusual glutamic acid residue in position P1Synthetic retinoid CD437 promotes rapid apoptosis in malignant human epidermal keratinocytes and G1 arrest in their normal counterparts.Mass-spectrometric analysis of agonist-induced retinoic acid receptor gamma conformational change.Activation of caspases and p53 by bovine herpesvirus 1 infection results in programmed cell death and efficient virus release.Computational identification of transcriptional regulators in human endotoxemiaSp1 and krüppel-like factor family of transcription factors in cell growth regulation and cancer.Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growthAspirin inhibits colon cancer cell and tumor growth and downregulates specificity protein (Sp) transcription factors.Dual induction of caspase 3- and transglutaminase-dependent apoptosis by acyclic retinoid in hepatocellular carcinoma cells.Fenretinide activates caspases and induces apoptosis in gliomas.Protein Mobility Shifts Contribute to Gel Electrophoresis Liquid Chromatography Analysis.Transcription factor Sp1, also known as specificity protein 1 as a therapeutic target.Induction of Egr-1 expression by the retinoid AHPN in human lung carcinoma cells is dependent on activated ERK1/2.An antagonist of retinoic acid receptors more effectively inhibits growth of human prostate cancer cells than normal prostate epithelium.Natural Products as Mechanism-based Anticancer Agents: Sp Transcription Factors as Targets.Eukaryotic translation initiation factor 4G is targeted for proteolytic cleavage by caspase 3 during inhibition of translation in apoptotic cells.Inhibition of IkappaB kinase by a new class of retinoid-related anticancer agents that induce apoptosis.Highly twisted adamantyl arotinoids: synthesis, antiproliferative effects and RXR transactivation profiles.Induction of apoptosis by KI0477959 through activation of caspase-3 in human leukemia cell line, HL-60 cells.Expression profiles of a human pancreatic cancer cell line upon induction of apoptosis search for modulators in cancer therapy.Early events in the induction of apoptosis in ovarian carcinoma cells by CD437: activation of the p38 MAP kinase signal pathway.Elucidation of molecular events mediating induction of apoptosis by synthetic retinoids using a CD437-resistant ovarian carcinoma cell line.Proteinase-3, a serine protease which mediates doxorubicin-induced apoptosis in the HL-60 leukemia cell line, is downregulated in its doxorubicin-resistant variant.The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages.Apoptotic response to growth factor deprivation involves cooperative interactions between c-Fos and p300.Mechanisms of apoptosis induced by the synthetic retinoid CD437 in human non-small cell lung carcinoma cells.Cleavage of transcription factor SP1 by caspases during anti-IgM-induced B-cell apoptosis.Selective activation of an apoptotic retinoid precursor in macrophage cell lines.Retinoic acid receptor-independent mechanism of apoptosis of melanoma cells by the retinoid CD437 (AHPN).Thioredoxin participates in a cell death pathway induced by interferon and retinoid combination.Lipopolysaccharide down-regulates Sp1 binding activity by promoting Sp1 protein dephosphorylation and degradation.Sp1 and NF-kappaB transcription factor activity in the regulation of the p21 and FasL promoters during promyelocytic leukemia cell monocytic differentiation and its associated apoptosis.Retinoid-related molecule AGN193198 potently induces G2M arrest and apoptosis in bladder cancer cells.Evidence for the Critical Roles of NF-κB p65 and Specificity Proteins in the Apoptosis-Inducing Activity of Proteasome Inhibitors in Leukemia Cells.Retinoid-related molecules require caspase 9 for the effective release of Smac and the rapid induction of apoptosis.Caspase cleavage of transcription factor Sp1 enhances apoptosis.
P2860
Q24531676-AE405B32-B20B-47EA-9ADF-F617987817DBQ24550911-1C9DB3AD-FA2F-4B8B-A579-7424A471011FQ28289604-DAE750F3-DC3A-4874-90C5-9FB46E0B786AQ28345397-70F91F14-6163-4370-B883-B1E54828EFA8Q28349126-0121BAE0-C31A-4BE7-841D-C5E33CA165C7Q31809899-31B19AFC-FC7D-4A08-8D84-3CC4144323E3Q32061962-89B032CC-4512-42E7-A2A4-3D26F70AF969Q33646578-CA06D766-132F-44B8-A17C-250111FD76A9Q33921020-58000BD7-D7DD-41BA-A7EB-5A082261B69EQ33952921-4C406472-3D4B-4E40-BF34-4C4E0DC0FC00Q33976179-1E37BD26-8F47-4A82-92CB-9D6DB697824EQ34461092-B771ABB2-DFF0-4816-ABF6-FEAF522B8BDDQ34506882-32A953B1-F023-4E00-8623-EC3795E4A0F3Q34876630-DABEC8D1-6C3B-4BAA-8CA7-A24240AC48C6Q35882806-8105D277-53DD-42A5-9966-7DEC5F5724C7Q38209122-E73C472D-C5FD-4C0F-B5B5-8A8D849F19B7Q38297130-2CDA5C9C-DD22-4D88-A24C-2D2880D3FECEQ38800583-9C29E2AB-8D6F-4CA4-AD96-438C2F9CDFF3Q38888042-810FD769-8E4A-4274-82A0-5A5B9DEAF114Q39577003-3396C5EE-A324-451D-80F2-5168ADDF3A5CQ39698764-725E76E3-6955-4E31-B0A1-957235439CF7Q39884072-5820987F-2A4E-4F58-9170-7F441C3BC74EQ39940579-D7975E83-252E-49B8-B076-EBF3E4A49983Q40489051-14E64D92-F79D-4550-8699-38DBEBDC931CQ40631549-0D05BF20-BF5B-49D8-AC3D-23EE3BB474E9Q40703405-D77181D7-34E1-4C70-A336-9556A1D879D5Q40715306-42752B2C-9CDE-4EBC-B40F-7E8A0AC7CDC9Q40816643-8472E89D-8014-4B06-86BB-28C0D450AFD2Q40894283-77522FE6-576B-48A5-9241-2D43D6D0C37FQ40954596-5F8435A9-2D13-4A9A-8690-5655512EDA26Q40963135-565B6A83-1934-4379-9F42-F9EF8EE7DD69Q41018777-41570E6B-C039-4970-867D-9BD14486A314Q42826124-F7892DEC-25DC-45A2-A4A0-4A6A15BA8275Q43663404-C6210182-51E9-42E6-A70F-722821D20BE4Q44044712-B504AE43-4D80-4DB5-9D81-ECE3BCC13A2FQ45230819-E739C4C8-0E47-4C42-B226-1FC796F349A9Q45281732-C767F947-0FC8-4AB8-A2A7-6BEDBCF06E5DQ45784186-D47CAAA1-1A54-45ED-ADCF-6432912FDC4CQ46577302-BA8327FC-7FF8-4A90-8F90-B6501BB6307CQ47298461-A9455744-2606-4A84-9FDB-F0DD58E38FF1
P2860
Retinoid-induced apoptosis and Sp1 cleavage occur independently of transcription and require caspase activation
description
1997 nî lūn-bûn
@nan
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Retinoid-induced apoptosis and ...... and require caspase activation
@ast
Retinoid-induced apoptosis and ...... and require caspase activation
@en
Retinoid-induced apoptosis and ...... and require caspase activation
@nl
type
label
Retinoid-induced apoptosis and ...... and require caspase activation
@ast
Retinoid-induced apoptosis and ...... and require caspase activation
@en
Retinoid-induced apoptosis and ...... and require caspase activation
@nl
prefLabel
Retinoid-induced apoptosis and ...... and require caspase activation
@ast
Retinoid-induced apoptosis and ...... and require caspase activation
@en
Retinoid-induced apoptosis and ...... and require caspase activation
@nl
P2860
P356
P1476
Retinoid-induced apoptosis and ...... and require caspase activation
@en
P2093
F J Piedrafita
P2860
P304
P356
10.1128/MCB.17.11.6348
P407
P577
1997-11-01T00:00:00Z