Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water
about
Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubesImpact of Genomics Platform and Statistical Filtering on Transcriptional Benchmark Doses (BMD) and Multiple Approaches for Selection of Chemical Point of Departure (PoD)BMDExpress Data Viewer - a visualization tool to analyze BMDExpress datasetsComparative transcriptomic analyses to scrutinize the assumption that genotoxic PAHs exert effects via a common mode of actionReduced biological effect of e-cigarette aerosol compared to cigarette smoke evaluated in vitro using normalized nicotine dose and RNA-seq-based toxicogenomics.Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment.Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK6 cells.High-Throughput Screening Data Interpretation in the Context of In Vivo Transcriptomic Responses to Oral Cr(VI) Exposure.Transcriptional profiling of the mouse hippocampus supports an NMDAR-mediated neurotoxic mode of action for benzo[a]pyrene.Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment.In Utero Exposure to Benzo[a]Pyrene Increases Mutation Burden in the Soma and Sperm of Adult Mice.Transcriptional benchmark dose modeling: Exploring how advances in chemical risk assessment may be applied to the radiation field.The TGx-28.65 biomarker online application for analysis of transcriptomics data to identify DNA damage-inducing chemicals in human cell cultures.Editor's Highlight: Application of Gene Set Enrichment Analysis for Identification of Chemically Induced, Biologically Relevant Transcriptomic Networks and Potential Utilization in Human Health Risk Assessment.Transcriptional Profiling of Dibenzo[def,p]chrysene-induced Spleen Atrophy Provides Mechanistic Insights into its Immunotoxicity in MutaMouse.Next generation sequencing of benzo(a)pyrene-induced lacZ mutants identifies a germ cell-specific mutation spectrum.Benzo(a)pyrene Is Mutagenic in Mouse Spermatogonial Stem Cells and Dividing Spermatogonia.Development and validation of a high-throughput transcriptomic biomarker to address 21st century genetic toxicology needs.Benchmark dose analyses of multiple genetic toxicity endpoints permit robust, cross-tissue comparisons of MutaMouse responses to orally delivered benzo[a]pyrene.Transcriptional profiling reveals gene expression changes associated with inflammation and cell proliferation following short-term inhalation exposure to copper oxide nanoparticles.In vitro RNA-seq-based toxicogenomics assessment shows reduced biological effect of tobacco heating products when compared to cigarette smoke.Impact of Acrylamide on Calcium Signaling and Cytoskeletal Filaments in Testes From F344 Rat.Bridging the Data Gap From Toxicity Testing to Chemical Safety Assessment Through Computational Modeling
P2860
Q28389674-781A4D84-1AF4-4FCA-9BA5-A420409AC1EEQ28547517-6713474A-6E7F-4146-A610-6D5B4FFC0FCAQ28821998-0C9F85F1-E420-4E66-BCA5-EC5A695DA2D5Q28828374-BDEA5B57-9C1F-4E6A-9DA5-106BF099516CQ30850313-D50831CF-DA55-42AD-AC44-9A1DE898D7CDQ33586230-838E6CCD-478A-4B0F-9DA6-EB9F40806BFDQ35862667-9EAD097C-684F-4CB0-BFE3-50FD95B06762Q36363468-0427B2BF-2D53-413A-B1A1-2DB5D1A2F277Q37025492-4A276F8A-C41F-40B7-84EF-1941FE40DDF7Q37561128-633179FB-7B3A-4516-A8C5-2FB3D1AE583BQ37580548-7221BFDA-200A-441E-8443-26E584BD5D8EQ38442981-212699C4-E427-489F-AB39-831E164DB2CEQ38647242-8A218573-5012-4993-8FF7-151AAFBC897BQ38998867-E5064427-2580-4582-ABE6-4CD1CB670D90Q40398064-CC14B6A0-445D-418E-BEE5-9829AB438A91Q41829529-C39B9DEA-8A43-4A51-B5DC-46D34A963105Q42101489-9CA575E3-BB93-4CBE-A2D1-BA5E530BEF76Q47171492-D6B0CF58-C9BC-4556-8118-4F9DC370F367Q47410180-F81B32BC-0B34-4AEC-9BCC-A5F3AF97B2A0Q47450436-C39B1F68-1BFC-4AD7-9D0C-E0710B696DF7Q50198135-03136EAA-3178-4E39-A2A0-F1F4320C7C89Q50732267-8546BB5A-E87E-439C-9C55-1476B83712B8Q58750452-7C018057-3DE8-4246-A8E4-1CC41A71FD7F
P2860
Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Comparison of toxicogenomics a ...... nzo[a]pyrene in drinking water
@ast
Comparison of toxicogenomics a ...... nzo[a]pyrene in drinking water
@en
Comparison of toxicogenomics a ...... nzo[a]pyrene in drinking water
@nl
type
label
Comparison of toxicogenomics a ...... nzo[a]pyrene in drinking water
@ast
Comparison of toxicogenomics a ...... nzo[a]pyrene in drinking water
@en
Comparison of toxicogenomics a ...... nzo[a]pyrene in drinking water
@nl
prefLabel
Comparison of toxicogenomics a ...... nzo[a]pyrene in drinking water
@ast
Comparison of toxicogenomics a ...... nzo[a]pyrene in drinking water
@en
Comparison of toxicogenomics a ...... nzo[a]pyrene in drinking water
@nl
P2093
P2860
P50
P3181
P1476
Comparison of toxicogenomics a ...... nzo[a]pyrene in drinking water
@en
P2093
Amal I Malik
Andrew Williams
Carol D Swartz
Daniel R Hyduke
France Lemieux
Ivy Moffat
Jiri Aubrecht
Julie Bourdon-Lacombe
Julie K Buick
P2860
P3181
P356
10.3109/10408444.2014.973934
P407
P577
2015-01-01T00:00:00Z