Protectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and Cancer
about
Inflammation, infection, cancer and all that…the role of paraoxonasesAntioxidant Functions of the Aryl Hydrocarbon ReceptorPON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell deathParaoxonase 2 serves a proapopotic function in mouse and human cells in response to the Pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-homoserine lactone.Macrophage paraoxonase 2 regulates calcium homeostasis and cell survival under endoplasmic reticulum stress conditions and is sufficient to prevent the development of aggravated atherosclerosis in paraoxonase 2 deficiency/apoE-/- mice on a Western dN-(3-oxo-acyl) homoserine lactone inhibits tumor growth independent of Bcl-2 proteins.Prostate tumor DNA methylation is associated with cigarette smoking and adverse prostate cancer outcomes.The anti-apoptotic PON2 protein is Wnt/β-catenin-regulated and correlates with radiotherapy resistance in OSCC patients.Decreased paraoxonase 2 enzymatic activity in monocyte/macrophages cells. A comparative in vivo and in vitro study for diabetes.Impact of Oxidative Stress on the Heart and Vasculature: Part 2 of a 3-Part Series.Paraoxonases-2 and -3 Are Important Defense Enzymes against Pseudomonas aeruginosa Virulence Factors due to Their Anti-Oxidative and Anti-Inflammatory Properties.The evolutionary origins of detoxifying enzymes: the mammalian serum paraoxonases (PONs) relate to bacterial homoserine lactonases.Dissecting gene-environment interactions: A penalized robust approach accounting for hierarchical structures.Trichostatin A preferentially reverses the upregulation of gene-expression levels induced by gain of chromosome 7 in colorectal cancer cell lines.Downregulation of paraoxonase 3 contributes to aggressive human hepatocellular carcinoma progression and associates with poor prognosis.Paraoxonase 2 overexpression inhibits tumor development in a mouse model of ovarian cancer.Using oxidant and antioxidant levels to predict the duration of both acute peripheral and mesenteric ischemia.Paraoxonase 3 is involved in the multi-drug resistance of esophageal cancerAssociation of Gene Polymorphisms (Ser311Cys and Ala148Gly) With the Risk of Developing Type 2 Diabetes Mellitus in the Chinese Population
P2860
Q26849832-D8966143-7E06-482B-801A-1CA41DB4A414Q28073170-B42BF418-987C-40CF-B3F6-DC22B70F83E4Q28387637-20E868E7-8A1D-49E5-9DD6-63DD4548CB19Q35172698-E106BAF4-A64D-4DEA-89DB-5AF954A1C32EQ36354408-B6FA7B82-F1D5-4544-9825-A62F615F7666Q36905804-755DB82E-0807-4225-B15B-2B486462709BQ37059172-0273EE02-41E6-44D2-928C-E820C8C04A9DQ37588244-A82989D5-418C-4D7E-84FF-DC534C28AF0DQ38699500-3DFB477F-6832-42FB-8FD6-85384F544C31Q39418950-5B554F74-23A9-4B50-A6F5-A81557FF54C8Q41856218-2246E54A-2EF9-4B6C-A26F-B35EEA8CEE39Q42235172-918DF426-8771-4AD0-BE76-8AE859CB1BEFQ47789970-E6252ABC-8CB0-48A3-8EA5-5CBF45EAD2C0Q48303232-DE75D18B-DF65-4096-BC5F-2222257EE5DCQ51555277-5227253C-AFB6-4462-AEB9-96D8FB22B98AQ52659536-333C59FE-C88D-4CF4-A557-B55EF0A34CDFQ53066004-CA5518C6-D58D-436F-948C-E10994224D0BQ58579141-D54D876F-D4FA-4BB9-B7DE-A4211DC52F06Q58700809-7B93E7FA-FB7B-49AD-ABA4-C6E17F59D976
P2860
Protectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and Cancer
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Protectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and Cancer
@ast
Protectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and Cancer
@en
Protectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and Cancer
@nl
type
label
Protectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and Cancer
@ast
Protectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and Cancer
@en
Protectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and Cancer
@nl
prefLabel
Protectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and Cancer
@ast
Protectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and Cancer
@en
Protectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and Cancer
@nl
P2093
P2860
P3181
P356
P1433
P1476
Protectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and Cancer
@en
P2093
Asokan Devarajan
Ines Witte
Srinivasa T Reddy
Ulrich Foerstermann
P2860
P304
P3181
P356
10.1155/2012/342806
P407
P50
P577
2012-05-13T00:00:00Z