Low concentration of arsenite exacerbates UVR-induced DNA strand breaks by inhibiting PARP-1 activity
about
Poly(ADP-ribose) polymerase-1 inhibition by arsenite promotes the survival of cells with unrepaired DNA lesions induced by UV exposureArsenic Inhibits DNA Mismatch Repair by Promoting EGFR Expression and PCNA Phosphorylation.Reduction of arsenite-enhanced ultraviolet radiation-induced DNA damage by supplemental zincArsenic-induced genotoxicity and genetic susceptibility to arsenic-related pathologiesInhibition of poly(ADP-ribose) polymerase-1 by arsenite interferes with repair of oxidative DNA damageArsenite interacts selectively with zinc finger proteins containing C3H1 or C4 motifsArsenic biotransformation as a cancer promoting factor by inducing DNA damage and disruption of repair mechanismsKinetics and thermodynamics of zinc(II) and arsenic(III) binding to XPA and PARP-1 zinc finger peptidesCombination of bifunctional alkylating agent and arsenic trioxide synergistically suppresses the growth of drug-resistant tumor cellsArsenite induced poly(ADP-ribosyl)ation of tumor suppressor P53 in human skin keratinocytes as a possible mechanism for carcinogenesis associated with arsenic exposure.Exposure to multiple metals from groundwater-a global crisis: geology, climate change, health effects, testing, and mitigation.Poly(ADP-ribose) contributes to an association between poly(ADP-ribose) polymerase-1 and xeroderma pigmentosum complementation group A in nucleotide excision repair.Inhibition of poly(ADP-ribose)polymerase-1 and DNA repair by uranium.Selective Sensitization of Zinc Finger Protein Oxidation by Reactive Oxygen Species through Arsenic Binding.Differential sensitivities of cellular XPA and PARP-1 to arsenite inhibition and zinc rescue.Arsenite-induced ROS/RNS generation causes zinc loss and inhibits the activity of poly(ADP-ribose) polymerase-1.Arsenite binding-induced zinc loss from PARP-1 is equivalent to zinc deficiency in reducing PARP-1 activity, leading to inhibition of DNA repair.The Sound of Silence: RNAi in Poly (ADP-Ribose) ResearchMelanocytes and keratinocytes have distinct and shared responses to ultraviolet radiation and arsenic.S-nitrosation on zinc finger motif of PARP-1 as a mechanism of DNA repair inhibition by arsenite.Abiotic stress and the plant circadian clockVersatile physiological functions of the Nudix hydrolase family in Arabidopsis.A semi-mechanistic integrated toxicokinetic-toxicodynamic (TK/TD) model for arsenic(III) in hepatocytesModulation of the poly(ADP-ribosyl)ation reaction via the Arabidopsis ADP-ribose/NADH pyrophosphohydrolase, AtNUDX7, is involved in the response to oxidative stress.Arsenite induces DNA damage via mitochondrial ROS and induction of mitochondrial permeability transition.Flavonoids inhibit chronically exposed arsenic-induced proliferation and malignant transformation of HaCaT cells.
P2860
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P2860
Low concentration of arsenite exacerbates UVR-induced DNA strand breaks by inhibiting PARP-1 activity
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Low concentration of arsenite ...... by inhibiting PARP-1 activity
@ast
Low concentration of arsenite ...... by inhibiting PARP-1 activity
@en
Low concentration of arsenite ...... by inhibiting PARP-1 activity
@nl
type
label
Low concentration of arsenite ...... by inhibiting PARP-1 activity
@ast
Low concentration of arsenite ...... by inhibiting PARP-1 activity
@en
Low concentration of arsenite ...... by inhibiting PARP-1 activity
@nl
prefLabel
Low concentration of arsenite ...... by inhibiting PARP-1 activity
@ast
Low concentration of arsenite ...... by inhibiting PARP-1 activity
@en
Low concentration of arsenite ...... by inhibiting PARP-1 activity
@nl
P2093
P2860
P1476
Low concentration of arsenite ...... by inhibiting PARP-1 activity
@en
P2093
Ke Jian Liu
Laurie G Hudson
Wenlan Liu
Xu-Jun Qin
P2860
P356
10.1016/J.TAAP.2008.05.019
P407
P577
2008-07-10T00:00:00Z