The retinal proteome in experimental diabetic retinopathy: up-regulation of crystallins and reversal by systemic and periocular insulin - Wikidata - wikimedia - TriplyDB

The retinal proteome in experimental diabetic retinopathy: up-regulation of crystallins and reversal by systemic and periocular insulin

The retinal proteome in experimental diabetic retinopathy: up-regulation of crystallins and reversal by systemic and periocular insulin

http://www.wikidata.org/entity/Q28388205

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Multi-modal proteomic analysis of retinal protein expression alterations in a rat model of diabetic retinopathy Differential roles of hyperglycemia and hypoinsulinemia in diabetes induced retinal cell death: evidence for retinal insulin resistance Transcriptome analysis using next generation sequencing reveals molecular signatures of diabetic retinopathy and efficacy of candidate drugs Transcriptomic comparison of the retina in two mouse models of diabetes A retinal proteomics-based study identifies αA-crystallin as a sex steroid-regulated protein.Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome.mTORC1-independent reduction of retinal protein synthesis in type 1 diabetes.Association of high myopia with crystallin beta A4 (CRYBA4) gene polymorphisms in the linkage-identified MYP6 locus.Alteration of growth factors and neuronal death in diabetic retinopathy: what we have learned so far.Sigma receptor 1 modulates endoplasmic reticulum stress in retinal neurons.Ocular proteomics with emphasis on two-dimensional gel electrophoresis and mass spectrometry.Alterations in energy metabolism, neuroprotection and visual signal transduction in the retina of Parkinsonian, MPTP-treated monkeys Strain-independent increases of crystallin proteins in the retina of type 1 diabetic rats.Glaucoma related Proteomic Alterations in Human Retina Samples Prediction of diabetic retinopathy: role of oxidative stress and relevance of apoptotic biomarkers.Bilberries potentially alleviate stress-related retinal gene expression induced by a high-fat diet in mice.Novel roles for α-crystallins in retinal function and disease.Crystallins and neuroinflammation: The glial side of the story.Subconjunctivally Implanted Hydrogels for Sustained Insulin Release to Reduce Retinal Cell Apoptosis in Diabetic Rats Effect of Korean Red Ginseng treatment on the gene expression profile of diabetic rat retina.Preservation of cone photoreceptors after a rapid yet transient degeneration and remodeling in cone-only Nrl-/- mouse retina RNA sequencing reveals retinal transcriptome changes in STZ-induced diabetic rats.Heat shock proteins in the retina: Focus on HSP70 and alpha crystallins in ganglion cell survival.Crystallins in retinal ganglion cell survival and regeneration.Retinal proteome alterations in a mouse model of type 2 diabetes.Pro-inflammatory cytokines downregulate Hsp27 and cause apoptosis of human retinal capillary endothelial cells.New focus on alpha-crystallins in retinal neurodegenerative diseases.Proteomic analysis of ophthalmic disease.Impact of diabetes on alpha-crystallins and other heat shock proteins in the eye.Recent technological developments in proteomics shed new light on translational research on diabetic microangiopathy.Diabetic retinopathy: loss of neuroretinal adaptation to the diabetic metabolic environment.Effects of crystallin-β-b2 on stressed RPE in vitro and in vivo.A Review: Proteomics in Retinal Artery Occlusion, Retinal Vein Occlusion, Diabetic Retinopathy and Acquired Macular Disorders.Chromatin features, RNA polymerase II and the comparative expression of lens genes encoding crystallins, transcription factors, and autophagy mediators In-Depth Proteomic Analysis of the Porcine Retina by Use of a four Step Differential Extraction Bottom up LC MS Platform.Suppression of GLUT1; a new strategy to prevent diabetic complications.Mutation screen of beta-crystallin genes in 274 patients with age-related macular degeneration.A specific phosphorylation regulates the protective role of αA-crystallin in diabetes.Proteomic Analysis of Early Diabetic Retinopathy Reveals Mediators of Neurodegenerative Brain Diseases.Integrated bioinformatic changes and analysis of retina with time in diabetic rats.

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The retinal proteome in experimental diabetic retinopathy: up-regulation of crystallins and reversal by systemic and periocular insulin

http://www.wikidata.org/entity/Q28388205

description

2009 nî lūn-bûn

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2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2009 թվականի ապրիլին հրատարակված գիտական հոդված

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2009年の論文

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The retinal proteome in experi ...... ystemic and periocular insulin

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The retinal proteome in experi ...... ystemic and periocular insulin

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Molecular & Cellular Proteomics

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Mandy K Losiewicz

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Ravi S J Singh

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P2860

A threshold neurotoxic amphetamine exposure inhibits parietal cortex expression of synaptic plasticity-related genes

Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis

Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex

Age-related changes in human lens crystallins identified by two-dimensional electrophoresis and mass spectrometry

betaA3/A1-crystallin in astroglial cells regulates retinal vascular remodeling during development

GammaD-crystallin associated protein aggregation and lens fiber cell denucleation

Insulin promotes rat retinal neuronal cell survival in a p70S6K-dependent manner.

Distinct proteomic profiles of amphetamine self-administration transitional states.

Synaptic pathology, altered gene expression, and degeneration in photoreceptors impacted by drusen.

Elongation of axons during regeneration involves retinal crystallin beta b2 (crybb2).

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