Limiting amounts of budding yeast Rad53 S-phase checkpoint activity results in increased resistance to DNA alkylation damage
about
Use of quantitative mass spectrometric analysis to elucidate the mechanisms of phospho-priming and auto-activation of the checkpoint kinase Rad53 in vivo.Reversal of PCNA ubiquitylation by Ubp10 in Saccharomyces cerevisiae.Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancerAnalysis of the tolerance to DNA alkylating damage in MEC1 and RAD53 checkpoint mutants of Saccharomyces cerevisiae.Cellular morphogenesis under stress is influenced by the sphingolipid pathway gene ISC1 and DNA integrity checkpoint genes in Saccharomyces cerevisiae.RAD53 is limiting in double-strand break repair and in protection against toxicity associated with ribonucleotide reductase inhibitionCds1 controls the release of Cdc14-like phosphatase Flp1 from the nucleolus to drive full activation of the checkpoint response to replication stress in fission yeast.Orderly progression through S-phase requires dynamic ubiquitylation and deubiquitylation of PCNA.Role of Dot1 in the response to alkylating DNA damage in Saccharomyces cerevisiae: regulation of DNA damage tolerance by the error-prone polymerases Polzeta/Rev1.Rad52 recruitment is DNA replication independent and regulated by Cdc28 and the Mec1 kinase.A cell cycle-regulated Slx4-Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication.Yeast-based assays for characterization of the functional effects of single nucleotide polymorphisms in human DNA repair genes.
P2860
Q27931778-A6E60359-8F10-4E96-80B8-E27B7CCA3585Q27934499-836EDC95-FB63-49E4-B50C-635D35EF9733Q34263742-98ED9576-D383-4C20-990F-DC66C0C8F01EQ35049451-B992CF54-989F-4EBF-BBFA-C467CE26AF06Q35297697-EAE41A8B-C955-4535-B9CD-1F2E1EA339B7Q36780916-2B55F08E-D9E3-48B7-84EE-1BB997CD772EQ38629893-249DA821-0D74-4DB1-865A-B09961800532Q39790257-183ABBC7-CEF0-4BA6-8770-6AA9070D533CQ40643647-5E933ED5-5BEB-45B1-9DAA-10C37ED97F5AQ41902708-67490DA3-AD82-4B7E-88A0-E56EED0D2A18Q42108506-553433B1-BB93-4082-8F91-9507C7B45FD4Q52727631-20CF61F0-FED0-46A3-84AE-7E4E3F3DA810
P2860
Limiting amounts of budding yeast Rad53 S-phase checkpoint activity results in increased resistance to DNA alkylation damage
description
2006 nî lūn-bûn
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Limiting amounts of budding ye ...... tance to DNA alkylation damage
@ast
Limiting amounts of budding ye ...... tance to DNA alkylation damage
@en
Limiting amounts of budding ye ...... tance to DNA alkylation damage
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type
label
Limiting amounts of budding ye ...... tance to DNA alkylation damage
@ast
Limiting amounts of budding ye ...... tance to DNA alkylation damage
@en
Limiting amounts of budding ye ...... tance to DNA alkylation damage
@nl
prefLabel
Limiting amounts of budding ye ...... tance to DNA alkylation damage
@ast
Limiting amounts of budding ye ...... tance to DNA alkylation damage
@en
Limiting amounts of budding ye ...... tance to DNA alkylation damage
@nl
P2860
P3181
P356
P1476
Limiting amounts of budding ye ...... tance to DNA alkylation damage
@en
P2093
Sandra Ufano
Violeta Cordón-Preciado
P2860
P304
P3181
P356
10.1093/NAR/GKL741
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P577
2006-10-24T00:00:00Z