Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection.
about
Age-related hearing impairment and the triad of acquired hearing loss.Reactive oxygen species, apoptosis, and mitochondrial dysfunction in hearing loss.Educational paper: do we need neonatal clinical pharmacologists?Comparing amikacin and kanamycin-induced hearing loss in multidrug-resistant tuberculosis treatment under programmatic conditions in a Namibian retrospective cohortEarly transcriptional response to aminoglycoside antibiotic suggests alternate pathways leading to apoptosis in sensory hair cells in the mouse inner earLoss of Slc4a1b chloride/bicarbonate exchanger function protects mechanosensory hair cells from aminoglycoside damage in the zebrafish mutant persephoneIntegrity and regeneration of mechanotransduction machinery regulate aminoglycoside entry and sensory cell death.Reduced TRMU expression increases the sensitivity of hair-cell-like HEI-OC-1 cells to neomycin damage in vitroAnti-apoptotic effect of dexamethasone in an ototoxicity modelDiphtheria Toxin-Induced Cell Death Triggers Wnt-Dependent Hair Cell Regeneration in Neonatal MiceGentamicin differentially alters cellular metabolism of cochlear hair cells as revealed by NAD(P)H fluorescence lifetime imaging.Noise-induced hearing loss: new animal models.Extracellular gentamicin reduces the activity of connexin hemichannels and interferes with purinergic Ca(2+) signaling in HeLa cells.The mitochondrion: a perpetrator of acquired hearing loss.Functional and structural changes throughout the auditory system following congenital and early-onset deafness: implications for hearing restoration.tmie Is required for gentamicin uptake by the hair cells of mice.Gentamicin rapidly inhibits mitochondrial metabolism in high-frequency cochlear outer hair cells.Designer aminoglycosides prevent cochlear hair cell loss and hearing lossInexhaustible hair-cell regeneration in young and aged zebrafish.Mitochondrial calcium uptake underlies ROS generation during aminoglycoside-induced hair cell deathNew trends in aminoglycosides use.Profiling drug-induced cell death pathways in the zebrafish lateral line.Aminoglycoside stress together with the 12S rRNA 1494C>T mutation leads to mitophagy.Population pharmacokinetics of gentamicin and dosing optimization for infantsUsing the zebrafish lateral line to uncover novel mechanisms of action and prevention in drug-induced hair cell deathNatural Bizbenzoquinoline Derivatives Protect Zebrafish Lateral Line Sensory Hair Cells from Aminoglycoside ToxicityGentamicin Exposure and Sensorineural Hearing Loss in Preterm InfantsMelatonin mitigates neomycin-induced hair cell injury in zebrafish.Suppression of premature termination codons as a therapeutic approach.Intrathecal 2-hydroxypropyl-beta-cyclodextrin in a single patient with Niemann-Pick C1.Sodium Selenite Acts as an Otoprotectant against Neomycin-Induced Hair Cell Damage in a Zebrafish Model.Activation of PI3K signaling prevents aminoglycoside-induced hair cell death in the murine cochlea.Designer aminoglycosides that selectively inhibit cytoplasmic rather than mitochondrial ribosomes show decreased ototoxicity: a strategy for the treatment of genetic diseases.Fluorescent aminoglycosides reveal intracellular trafficking routes in mechanosensory hair cells.Autophagic flux, a possible mechanism for delayed gentamicin-induced ototoxicity.Therapeutics based on stop codon readthrough.Nonsense Suppression as an Approach to Treat Lysosomal Storage Diseases.The role of intracochlear drug delivery devices in the management of inner ear disease.Safety and tolerability profile of second-line anti-tuberculosis medications.Risk of gentamicin toxicity in neonates treated for possible severe bacterial infection in low- and middle-income countries: Systematic Review.
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P2860
Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection.
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection
@nl
Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection.
@ast
Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection.
@en
type
label
Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection
@nl
Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection.
@ast
Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection.
@en
prefLabel
Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection
@nl
Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection.
@ast
Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection.
@en
P2093
P2860
P3181
P356
P1476
Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection.
@en
P2093
P2860
P304
P3181
P356
10.1155/2011/937861
P407
P577
2011-10-25T00:00:00Z