Inhibition of mitochondrial protein import by mutant huntingtin
about
Cardiolipin signaling mechanisms: collapse of asymmetry and oxidationThe chicken or the egg: mitochondrial dysfunction as a cause or consequence of toxicity in Huntington's diseaseDifferential Protein Distribution between the Nucleus and Mitochondria: Implications in AgingOxygen consumption deficit in Huntington disease mouse brain under metabolic stressFUS Interacts with HSP60 to Promote Mitochondrial DamageThe Truncated C-terminal Fragment of Mutant ATXN3 Disrupts Mitochondria Dynamics in Spinocerebellar Ataxia Type 3 Models.Mitochondrial DNA levels in Huntington disease leukocytes and dermal fibroblasts.The Broad Impact of TOM40 on Neurodegenerative Diseases in AgingImpaired import: how huntingtin harms.Spectrum of combined respiratory chain defects.Calcium Handling by Endoplasmic Reticulum and Mitochondria in a Cell Model of Huntington's Disease.Oxidative metabolism in YAC128 mouse model of Huntington's disease.Folding Landscape of Mutant Huntingtin Exon1: Diffusible Multimers, Oligomers and Fibrils, and No Detectable Monomer.Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease.Inhibition of DNA Methyltransferases Blocks Mutant Huntingtin-Induced NeurotoxicityVCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease.Amyloid β-peptides interfere with mitochondrial preprotein import competence by a coaggregation process.Oxidative metabolism and Ca2+ handling in isolated brain mitochondria and striatal neurons from R6/2 mice, a model of Huntington's disease.Oxidative Stress and Huntington's Disease: The Good, The Bad, and The Ugly.Role of mitochondrial raft-like microdomains in the regulation of cell apoptosis.Protein translocation channel of mitochondrial inner membrane and matrix-exposed import motor communicate via two-domain coupling protein.Mutant Huntingtin and Elusive Defects in Oxidative Metabolism and Mitochondrial Calcium Handling.The role of DNA base excision repair in brain homeostasis and disease.Huntington's Disease: Pathogenic Mechanisms and Therapeutic Targets.Modulation of Molecular Chaperones in Huntington's Disease and Other Polyglutamine Disorders.Faulty splicing and cytoskeleton abnormalities in Huntington's disease.Oxidative metabolism and Ca2+ handling in striatal mitochondria from YAC128 mice, a model of Huntington's disease.Huntington's Disease: Mechanisms of Pathogenesis and Therapeutic Strategies.Comparative Mitochondrial-Based Protective Effects of Resveratrol and Nicotinamide in Huntington's Disease Models.Methylene Blue Partially Rescues Heart Defects in a Drosophila Model of Huntington's Disease.Quantitative Proteomic Analysis Reveals Similarities between Huntington's Disease (HD) and Huntington's Disease-Like 2 (HDL2) Human Brains.Altered Co-Translational Processing Plays a Role in Huntington's Pathogenesis-A Hypothesis.Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat.Moving toward a gene therapy for Huntington's disease.HACE1 is essential for astrocyte mitochondrial function and influences Huntington disease phenotypes in vivo.Towards an Understanding of Energy Impairment in Huntington's Disease Brain.Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington's Disease Model through the Application of Quantitative Systems Pharmacology.Searching for Correlations Between the Development of Neurodegenerative Hallmarks: Targeting Huntingtin as a Contributing Factor.Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release.Design of Bivalent Nucleic Acid Ligands for Recognition of RNA-Repeated Expansion Associated with Huntington's Disease.
P2860
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P2860
Inhibition of mitochondrial protein import by mutant huntingtin
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Inhibition of mitochondrial protein import by mutant huntingtin
@ast
Inhibition of mitochondrial protein import by mutant huntingtin
@en
Inhibition of mitochondrial protein import by mutant huntingtin
@nl
type
label
Inhibition of mitochondrial protein import by mutant huntingtin
@ast
Inhibition of mitochondrial protein import by mutant huntingtin
@en
Inhibition of mitochondrial protein import by mutant huntingtin
@nl
prefLabel
Inhibition of mitochondrial protein import by mutant huntingtin
@ast
Inhibition of mitochondrial protein import by mutant huntingtin
@en
Inhibition of mitochondrial protein import by mutant huntingtin
@nl
P2093
P2860
P3181
P356
P1433
P1476
Inhibition of mitochondrial protein import by mutant huntingtin
@en
P2093
Albert H Kim
Diane L Carlisle
Hiroko Yano
Oxana V Baranova
Robert M Friedlander
Sergei V Baranov
Svitlana Yablonska
Yanchun Pan
P2860
P2888
P304
P3181
P356
10.1038/NN.3721
P407
P577
2014-06-01T00:00:00Z
P5875
P6179
1040858938