Inhibition of mitochondrial protein import by mutant huntingtin - Wikidata - wikimedia - TriplyDB

Inhibition of mitochondrial protein import by mutant huntingtin

Inhibition of mitochondrial protein import by mutant huntingtin

http://www.wikidata.org/entity/Q28394803

about

Cardiolipin signaling mechanisms: collapse of asymmetry and oxidation The chicken or the egg: mitochondrial dysfunction as a cause or consequence of toxicity in Huntington's disease Differential Protein Distribution between the Nucleus and Mitochondria: Implications in Aging Oxygen consumption deficit in Huntington disease mouse brain under metabolic stress FUS Interacts with HSP60 to Promote Mitochondrial Damage The Truncated C-terminal Fragment of Mutant ATXN3 Disrupts Mitochondria Dynamics in Spinocerebellar Ataxia Type 3 Models.Mitochondrial DNA levels in Huntington disease leukocytes and dermal fibroblasts.The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging Impaired import: how huntingtin harms.Spectrum of combined respiratory chain defects.Calcium Handling by Endoplasmic Reticulum and Mitochondria in a Cell Model of Huntington's Disease.Oxidative metabolism in YAC128 mouse model of Huntington's disease.Folding Landscape of Mutant Huntingtin Exon1: Diffusible Multimers, Oligomers and Fibrils, and No Detectable Monomer.Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease.Inhibition of DNA Methyltransferases Blocks Mutant Huntingtin-Induced Neurotoxicity VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease.Amyloid β-peptides interfere with mitochondrial preprotein import competence by a coaggregation process.Oxidative metabolism and Ca2+ handling in isolated brain mitochondria and striatal neurons from R6/2 mice, a model of Huntington's disease.Oxidative Stress and Huntington's Disease: The Good, The Bad, and The Ugly.Role of mitochondrial raft-like microdomains in the regulation of cell apoptosis.Protein translocation channel of mitochondrial inner membrane and matrix-exposed import motor communicate via two-domain coupling protein.Mutant Huntingtin and Elusive Defects in Oxidative Metabolism and Mitochondrial Calcium Handling.The role of DNA base excision repair in brain homeostasis and disease.Huntington's Disease: Pathogenic Mechanisms and Therapeutic Targets.Modulation of Molecular Chaperones in Huntington's Disease and Other Polyglutamine Disorders.Faulty splicing and cytoskeleton abnormalities in Huntington's disease.Oxidative metabolism and Ca2+ handling in striatal mitochondria from YAC128 mice, a model of Huntington's disease.Huntington's Disease: Mechanisms of Pathogenesis and Therapeutic Strategies.Comparative Mitochondrial-Based Protective Effects of Resveratrol and Nicotinamide in Huntington's Disease Models.Methylene Blue Partially Rescues Heart Defects in a Drosophila Model of Huntington's Disease.Quantitative Proteomic Analysis Reveals Similarities between Huntington's Disease (HD) and Huntington's Disease-Like 2 (HDL2) Human Brains.Altered Co-Translational Processing Plays a Role in Huntington's Pathogenesis-A Hypothesis.Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat.Moving toward a gene therapy for Huntington's disease.HACE1 is essential for astrocyte mitochondrial function and influences Huntington disease phenotypes in vivo.Towards an Understanding of Energy Impairment in Huntington's Disease Brain.Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington's Disease Model through the Application of Quantitative Systems Pharmacology.Searching for Correlations Between the Development of Neurodegenerative Hallmarks: Targeting Huntingtin as a Contributing Factor.Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release.Design of Bivalent Nucleic Acid Ligands for Recognition of RNA-Repeated Expansion Associated with Huntington's Disease.

P2860

Q23923191-837DB773-E33B-4540-A2A2-4A9A5B0DF504 Q28072937-F094D4C0-F3C3-48D6-A2F8-E9829C09469B Q28075214-4454EFEE-806F-4C51-ACD1-E01D3AE9E3A4 Q28397230-4C8B9FA3-6256-4182-9F4D-F25B73087B6A Q28547727-C317E155-BF3D-44A3-8DF0-BB5113C20C40 Q33813373-3ED32C5D-6C7A-408F-9C26-2654C5B9F93F Q33890630-1D7986E0-CAEA-4963-A7E0-374CC50501A9 Q35137172-A26F46F0-C98A-42BC-9875-FDDDBBD07ACD Q35664881-66A2B02C-B9F0-4482-A0AC-66A5FBFF718C Q35825509-7D394EA8-F847-4ED6-96D9-F101B9562F70 Q35906784-6106B93A-3558-4F19-BBB5-34128FD89ADE Q35924062-8D5FD9BE-45B2-4E8D-A73C-5B986466C7E6 Q36043574-EFAF57DA-0F4A-47B1-839A-A2B5F11F8E1A Q36159463-FD2FA96B-F23A-4170-A194-D2C85CB03ED4 Q37169118-52E052DC-8DBA-47DD-B2A2-5B74616C9579 Q37223339-C3ED2C61-8671-45CF-AD91-9F0B6BC64DE5 Q37518239-0A23DFDD-528E-466A-8DD5-A760EE11111E Q37530288-3C9952A8-2179-455A-938D-6022DE9B9C12 Q37643688-64AA0D73-F22C-40CF-BE0C-EDC9001DDA85 Q38344567-CDBC04EC-F290-49E6-B0A9-7E412D8BE6BC Q38358839-85918945-E61B-4A0F-82B5-E6A73F0D3DC4 Q38458943-E63564CF-2A82-4DFC-AE76-FB87CDE3126F Q38498842-66CDD2B8-D652-422E-A253-ECF67CC2AD74 Q38663090-2E87A872-11DA-4BD6-AA63-ECD128B05954 Q38818474-8821FEC4-48CA-4C13-8055-1EECD66400A3 Q38928751-7359E329-402F-42E9-8EC2-3A047F759A00 Q39035184-2AEEE89F-CEB6-46D8-8127-513D13188136 Q39035495-09F3D314-D30A-4F8C-B33D-842D8150814C Q39427235-05F71A3C-8A89-4E7A-9EE1-B0D5CBD2846B Q40511148-29389ECB-2923-4C39-BBBA-3D5932B67EAD Q41377417-F08F0100-710D-4989-AD16-11844F90A207 Q41851500-CF51AB29-4FFA-45DB-8530-9954A837AD3D Q45290815-821F96A4-1A16-4106-9701-8FC4717D2781 Q45291688-05675392-E595-47CE-AD01-29F66565565C Q45305356-ABA4B7B1-2876-412A-84AB-A4EBDD41EE34 Q47442924-185863DB-7C57-4A87-A7DB-64F733BB70C2 Q47564614-4C035081-AC28-4074-B18C-36522C1DDB8F Q47710910-84DC9C6A-1138-48AB-A4D0-9F56ABCDCF70 Q47851900-31257C18-2711-4BC6-89A7-0A11F39167F1 Q51737120-16E5DCDA-FD12-42AB-A329-D1581E86EE32

P2860

Inhibition of mitochondrial protein import by mutant huntingtin

http://www.wikidata.org/entity/Q28394803

description

2014 nî lūn-bûn

@nan

2014 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Inhibition of mitochondrial protein import by mutant huntingtin

@ast

Inhibition of mitochondrial protein import by mutant huntingtin

@en

Inhibition of mitochondrial protein import by mutant huntingtin

@nl

type

label

Inhibition of mitochondrial protein import by mutant huntingtin

@ast

Inhibition of mitochondrial protein import by mutant huntingtin

@en

Inhibition of mitochondrial protein import by mutant huntingtin

@nl

prefLabel

Inhibition of mitochondrial protein import by mutant huntingtin

@ast

Inhibition of mitochondrial protein import by mutant huntingtin

@en

Inhibition of mitochondrial protein import by mutant huntingtin

@nl

P1433

Q28394803-D14F8D52-4FB3-4673-B53A-74594CA9FA1C

P1476

Q28394803-B31C8E98-8D83-42F7-8DAD-5EFC875B8AAF

P2093

Q28394803-58BEF70B-5E45-42F2-A3C5-B62DA50C4587

Q28394803-59FB62B0-40FD-41C2-8C05-95A8774AB1F3

Q28394803-7E0B50EB-2601-4079-92F0-78D185A01256

Q28394803-878D3087-28FB-4668-9EFB-D81153FA2947

Q28394803-91435FB2-2DC4-4249-8A00-C1125B66C8EF

Q28394803-9F27E433-3005-49F2-8C81-FDF0692BF3A9

Q28394803-ADEA864A-C72B-4AF1-B978-3A25A0EBF39A

Q28394803-ECFB0692-D63B-424C-8FEA-ABB93A77A407

Q28394803-F0ABAA1D-3847-4FE8-A920-097C1ABFD734

P2860

Q28394803-0158D708-8736-4310-BBFE-030B96610B36

Q28394803-05307E77-899F-45AD-BAF0-B09B53A135E3

Q28394803-0A84E5C9-5300-4323-9631-D980044F3722

Q28394803-164AA3EF-98DB-4832-808F-6C83F11146FE

Q28394803-1A929C08-8CD5-4DA9-B786-CF8216C714A4

Q28394803-1D261C88-3C4B-411D-9C3D-8E07D0F83EEC

Q28394803-2D31672D-E2E8-4AE4-8E7D-1448B54B99B9

Q28394803-363A6B24-9614-4BC2-8EBD-BC78EDB275A8

Q28394803-36AAA288-ED9D-45EB-87B4-C0E1897C5BB5

Q28394803-39BA36A6-45B0-4C35-BE45-44C9D2013660

P2888

Q28394803-C638C891-D713-4596-9B26-1A39F7996FC1

P304

Q28394803-17E97870-CF93-42B7-8122-20FF1B078E19

P31

Q28394803-AB479834-5BA0-4558-BD2D-CC05036D2DEC

P3181

Q28394803-F40A732D-0C05-4954-B833-37830AA02258

P356

Q28394803-130F548F-0521-4435-8FA8-8C5475EB67D4

P407

Q28394803-8BA4CA0A-E7C9-455F-9FC9-27A2D7239D37

P433

Q28394803-E7A9197E-AC09-41ED-A822-BA0803425652

P478

Q28394803-5DC15F2C-D78D-4C96-96CC-D32FE4F894DB

P50

Q28394803-F2817322-F2AB-4567-A8C3-2CDC3C96C691

P577

Q28394803-DEB1AA2A-26B9-4CB7-990E-A305EE764EDE

P5875

Q28394803-8F2C49F4-0017-4006-8302-A7CDF5B44524

P6179

Q28394803-CA2E8B9C-78CE-4F09-97AE-057A0F07702B

P698

Q28394803-73F17795-9987-4947-A929-AB7DF5FC8709

P921

Q28394803-7D5AB719-4224-481E-8BA8-A9D36BC3455A

P932

Q28394803-4994AF81-5A9A-4CCF-8ED5-98470B3C3DE3

P3181

P356

P1433

Nature Neuroscience

P1476

Inhibition of mitochondrial protein import by mutant huntingtin

@en

P2093

Albert H Kim

http://www.w3.org/2001/XMLSchema#string

Diane L Carlisle

http://www.w3.org/2001/XMLSchema#string

Hiroko Yano

http://www.w3.org/2001/XMLSchema#string

Jinho Kim

http://www.w3.org/2001/XMLSchema#string

Oxana V Baranova

http://www.w3.org/2001/XMLSchema#string

Robert M Friedlander

http://www.w3.org/2001/XMLSchema#string

Sergei V Baranov

http://www.w3.org/2001/XMLSchema#string

Svitlana Yablonska

http://www.w3.org/2001/XMLSchema#string

Yanchun Pan

http://www.w3.org/2001/XMLSchema#string

P2860

Early alterations of brain cellular energy homeostasis in Huntington disease models

A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons

Dissection of the mitochondrial import and assembly pathway for human Tom40

Identification and functional analysis of human Tom22 for protein import into mitochondria

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae.

The mitochondrial morphology protein Mdm10 functions in assembly of the preprotein translocase of the outer membrane.

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

Huntingtin aggregation and toxicity in Huntington's disease

Human deafness dystonia syndrome is caused by a defect in assembly of the DDP1/TIMM8a-TIMM13 complex

P2888

P304

822-31

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1018465

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/NN.3721

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

17

http://www.w3.org/2001/XMLSchema#string

P50

Robert J Ferrante

P577

2014-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

262421236

http://www.w3.org/2001/XMLSchema#string

P6179

1040858938

http://www.w3.org/2001/XMLSchema#string

P698

24836077

http://www.w3.org/2001/XMLSchema#string

P921

P932

4174557

http://www.w3.org/2001/XMLSchema#string