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Functions of the nonsense-mediated mRNA decay pathway in Drosophila development

Functions of the nonsense-mediated mRNA decay pathway in Drosophila development

http://www.wikidata.org/entity/Q28469087

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Mechanism and regulation of the nonsense-mediated decay pathway Ribonucleoprotein complexes that control circadian clocks SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians In vivo monitoring of mRNA movement in Drosophila body wall muscle cells reveals the presence of myofiber domains Physiological basis of copper tolerance of Saccharomyces cerevisiae nonsense-mediated mRNA decay mutants.Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story Alternative splicing regulation during C. elegans development: splicing factors as regulated targets.Contribution of copy number variants involving nonsense-mediated mRNA decay pathway genes to neuro-developmental disorders.High-resolution profiling of NMD targets in yeast reveals translational fidelity as a basis for substrate selection.VHL frameshift mutation as target of nonsense-mediated mRNA decay in Drosophila melanogaster and human HEK293 cell line.Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal system.Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay.Is there a classical nonsense-mediated decay pathway in trypanosomes?The nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy.Drosophila Upf1 and Upf2 loss of function inhibits cell growth and causes animal death in a Upf3-independent manner Ubiquitin over-expression phenotypes and ubiquitin gene molecular misreading during aging in Drosophila melanogaster Intron retention in the Drosophila melanogaster Rieske Iron Sulphur Protein gene generated a new protein.Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question.The Wright stuff: reimagining path analysis reveals novel components of the sex determination hierarchy in Drosophila melanogaster.A whole-genome analysis of premature termination codons.Caenorhabditis elegans SMG-2 selectively marks mRNAs containing premature translation termination codons.Navigating without a road map Aberrant growth and lethality of Arabidopsis deficient in nonsense-mediated RNA decay factors is caused by autoimmune-like response.Drosophila mutants show NMD pathway activity is reduced, but not eliminated, in the absence of Smg6 Nonsense-mediated mRNA decay and development: shoot the messenger to survive?mRNA quality control: an ancient machinery recognizes and degrades mRNAs with nonsense codons.Degradation of Gadd45 mRNA by nonsense-mediated decay is essential for viability.The multiple lives of NMD factors: balancing roles in gene and genome regulation Regulated protein depletion by the auxin-inducible degradation system in Drosophila melanogaster A gripping tale of ribosomal frameshifting: extragenic suppressors of frameshift mutations spotlight P-site realignment.Alternative splicing and the steady-state ratios of mRNA isoforms generated by it are under strong stabilizing selection in Caenorhabditis elegans In vivo determination of direct targets of the nonsense-mediated decay pathway in Drosophila.Rapid identification of mRNA processing defects with a novel single-cell yeast reporter Tube continued: morphogenesis of the Drosophila tracheal system.NMD: RNA biology meets human genetic medicine.UPF1 involvement in nuclear functions.Regulation of nonsense-mediated mRNA decay.Nonsense-mediated mRNA decay: from mechanistic insights to impacts on human health.Regulation of natural mRNAs by the nonsense-mediated mRNA decay pathway.

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Functions of the nonsense-mediated mRNA decay pathway in Drosophila development

http://www.wikidata.org/entity/Q28469087

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2006 nî lūn-bûn

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2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Functions of the nonsense-mediated mRNA decay pathway in Drosophila development

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Functions of the nonsense-mediated mRNA decay pathway in Drosophila development

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Functions of the nonsense-mediated mRNA decay pathway in Drosophila development

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Functions of the nonsense-mediated mRNA decay pathway in Drosophila development

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Functions of the nonsense-mediated mRNA decay pathway in Drosophila development

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Functions of the nonsense-mediated mRNA decay pathway in Drosophila development

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Functions of the nonsense-mediated mRNA decay pathway in Drosophila development

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Functions of the nonsense-mediated mRNA decay pathway in Drosophila development

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Functions of the nonsense-mediated mRNA decay pathway in Drosophila development

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JOURNAL.PGEN.0020180

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Functions of the nonsense-mediated mRNA decay pathway in Drosophila development

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Mark A Krasnow

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Mark M Metzstein

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P2860

Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon

Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

The human RNA surveillance factor UPF1 is required for S phase progression and genome stability

Splicing enhances translation in mammalian cells: an additional function of the exon junction complex

Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways

FlyGEM, a full transcriptome array platform for the Drosophila community

Nonsense-mediated mRNA decay: from vacuum cleaner to Swiss army knife

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

Targeting of aberrant mRNAs to cytoplasmic processing bodies.

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