DARPP-32 is a robust integrator of dopamine and glutamate signals
about
Mechanisms for the modulation of dopamine d(1) receptor signaling in striatal neuronsComputational systems analysis of dopamine metabolismModeling intracellular signaling underlying striatal function in health and diseaseMolecular, cellular, and structural mechanisms of cocaine addiction: a key role for microRNAsRole of DARPP-32 and ARPP-21 in the Emergence of Temporal Constraints on Striatal Calcium and Dopamine IntegrationDendritic geometry shapes neuronal cAMP signalling to the nucleusThe internal state of medium spiny neurons varies in response to different input signalsSubcellular location of PKA controls striatal plasticity: stochastic simulations in spiny dendritesA kinetic model of dopamine- and calcium-dependent striatal synaptic plasticityTransfer functions for protein signal transduction: application to a model of striatal neural plasticityIntegration of biochemical and electrical signaling-multiscale model of the medium spiny neuron of the striatumSTEPS: efficient simulation of stochastic reaction-diffusion models in realistic morphologiesPredicted functions of MdmX in fine-tuning the response of p53 to DNA damage.Effects of DARPP-32 Genetic Variation on Prefrontal Cortex Volume and Episodic Memory Performance.Dopamine and psychosis: theory, pathomechanisms and intermediate phenotypesCyclin-dependent kinase 5, a node protein in diminished tauopathy: a systems biology approach.A protein kinase A-independent pathway controlling aquaporin 2 trafficking as a possible cause for the syndrome of inappropriate antidiuresis associated with polycystic kidney disease 1 haploinsufficiencyThe neurobiology of alcohol consumption and alcoholism: an integrative historySignaling pathways involved in striatal synaptic plasticity are sensitive to temporal pattern and exhibit spatial specificity.Spatial distribution of DARPP-32 in dendritic spines.Regulation of Neuronal Function by Ras-GRF Exchange Factors.Beyond the dopamine receptor: regulation and roles of serine/threonine protein phosphatases.DARPP-32, Jack of All Trades… Master of Which?The cannabinoid agonist WIN55212-2 decreases L-DOPA-induced PKA activation and dyskinetic behavior in 6-OHDA-treated ratsImaging brain signal transduction and metabolism via arachidonic and docosahexaenoic acid in animals and humans.Effects of protein kinase A inhibitor and activator on rewarding effects of SKF-82958 microinjected into nucleus accumbens shell of ad libitum fed and food-restricted rats.Regulation of Nociceptive Plasticity Threshold and DARPP-32 Phosphorylation in Spinal Dorsal Horn Neurons by Convergent Dopamine and Glutamate InputsA mathematical tool for exploring the dynamics of biological networks.Activation of Protein Kinases and Phosphatases Coupled to Glutamate Receptors Regulates the Phosphorylation State of DARPP32 at Threonine 75 After Repeated Exposure to Cocaine in the Rat Dorsal Striatum in a Ca2+-Dependent MannerModelling the molecular mechanisms of synaptic plasticity using systems biology approachesMapping brain metabolic connectivity in awake rats with μPET and optogenetic stimulationIs DARPP-32 a potential therapeutic target?Mechanisms of locomotor sensitization to drugs of abuse in a two-injection protocol.MicroRNAs in Schizophrenia: Implications for Synaptic Plasticity and Dopamine-Glutamate Interaction at the Postsynaptic Density. New Avenues for Antipsychotic Treatment Under a Theranostic Perspective.Toward integration of biological and physiological functions at multiple levels.The evolutionary strata of DARPP-32 tail implicates hierarchical functional expansion in higher vertebrates.Postsynaptic signal transduction models for long-term potentiation and depression.A novel tyrosine kinase inhibitor AMN107 (nilotinib) normalizes striatal motor behaviors in a mouse model of Parkinson's disease.Casein kinase 1 enables nucleus accumbens amphetamine-induced locomotion by regulating AMPA receptor phosphorylation.Dopamine signaling negatively regulates striatal phosphorylation of Cdk5 at tyrosine 15 in mice.
P2860
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P2860
DARPP-32 is a robust integrator of dopamine and glutamate signals
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
DARPP-32 is a robust integrator of dopamine and glutamate signals
@ast
DARPP-32 is a robust integrator of dopamine and glutamate signals
@en
DARPP-32 is a robust integrator of dopamine and glutamate signals
@nl
type
label
DARPP-32 is a robust integrator of dopamine and glutamate signals
@ast
DARPP-32 is a robust integrator of dopamine and glutamate signals
@en
DARPP-32 is a robust integrator of dopamine and glutamate signals
@nl
prefLabel
DARPP-32 is a robust integrator of dopamine and glutamate signals
@ast
DARPP-32 is a robust integrator of dopamine and glutamate signals
@en
DARPP-32 is a robust integrator of dopamine and glutamate signals
@nl
P2860
P50
P3181
P1476
DARPP-32 is a robust integrator of dopamine and glutamate signals
@en
P2093
Eric Fernandez
P2860
P3181
P356
10.1371/JOURNAL.PCBI.0020176
P407
P577
2006-12-22T00:00:00Z