Function-altering SNPs in the human multidrug transporter gene ABCB1 identified using a Saccharomyces-based assay
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Regulatory pathways for ATP-binding cassette transport proteins in kidney proximal tubulesMacrocyclic lactones differ in interaction with recombinant P-glycoprotein 9 of the parasitic nematode Cylicocylus elongatus and ketoconazole in a yeast growth assayA synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.Clinical significance of ABCB1 genotyping in oncology.The pharmacogenomics of membrane transporters project: research at the interface of genomics and transporter pharmacology.Drug resistance is conferred on the model yeast Saccharomyces cerevisiae by expression of full-length melanoma-associated human ATP-binding cassette transporter ABCB5.Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains.Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selectionDoxorubicin pathways: pharmacodynamics and adverse effects.Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiaeMutability and mutational spectrum of chromosome transmission fidelity genesSTUbLs in chromatin and genome stability.Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structureAn extended set of yeast-based functional assays accurately identifies human disease mutations.The human multidrug resistance protein 4 (MRP4, ABCC4): functional analysis of a highly polymorphic gene.Fetal polymorphisms at the ABCB1-transporter gene locus are associated with susceptibility to non-syndromic oral cleft malformations.An update on ABCB1 pharmacogenetics: insights from a 3D model into the location and evolutionary conservation of residues corresponding to SNPs associated with drug pharmacokinetics.Pharmacogenetics of genes across the doxorubicin pathway.The effect of ABCB1 genetic variants on chemotherapy response in HIV and cancer treatment.Pharmacogenetics of taxanes: impact of gene polymorphisms of drug transporters on pharmacokinetics and toxicity.Polymorphisms of the drug transporters ABCB1, ABCG2, ABCC2 and ABCC3 and their impact on drug bioavailability and clinical relevance.Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature.ABCC2 (1249G > A) polymorphism implicates altered transport activity for sorafenib.Substrate-dependent effects of human ABCB1 coding polymorphismsPredictable difficulty or difficulty to predict.Evolutionarily Conserved Roles for Blood-Brain Barrier Xenobiotic Transporters in Endogenous Steroid Partitioning and Behavior.Response to “Predictable difficulty or difficulty to predict”.
P2860
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P2860
Function-altering SNPs in the human multidrug transporter gene ABCB1 identified using a Saccharomyces-based assay
description
2007 nî lūn-bûn
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2007 թուականի Մարտին հրատարակուած գիտական յօդուած
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2007 թվականի մարտին հրատարակված գիտական հոդված
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2007年の論文
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2007年論文
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2007年論文
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2007年論文
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2007年論文
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2007年論文
@zh-tw
2007年论文
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name
Function-altering SNPs in the ...... ng a Saccharomyces-based assay
@ast
Function-altering SNPs in the ...... ng a Saccharomyces-based assay
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Function-altering SNPs in the ...... ng a Saccharomyces-based assay
@nl
type
label
Function-altering SNPs in the ...... ng a Saccharomyces-based assay
@ast
Function-altering SNPs in the ...... ng a Saccharomyces-based assay
@en
Function-altering SNPs in the ...... ng a Saccharomyces-based assay
@nl
prefLabel
Function-altering SNPs in the ...... ng a Saccharomyces-based assay
@ast
Function-altering SNPs in the ...... ng a Saccharomyces-based assay
@en
Function-altering SNPs in the ...... ng a Saccharomyces-based assay
@nl
P2093
P2860
P3181
P1433
P1476
Function-altering SNPs in the ...... ng a Saccharomyces-based assay
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P2093
Deanna L Kroetz
Hotcherl Jeong
Ira Herskowitz
Jasper Rine
P2860
P3181
P356
10.1371/JOURNAL.PGEN.0030039
P407
P577
2007-03-09T00:00:00Z