Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes
about
The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapseThe molecular basis of cognitive deficits in pervasive developmental disordersAtypical regulation of G protein-coupled receptor intracellular trafficking by ubiquitinationDysbindin-containing complexes and their proposed functions in brain: from zero to (too) many in a decade.Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains.The role of ubiquitination in lysosomal trafficking of δ-opioid receptors.G protein-coupled receptor-associated sorting protein 1 regulates the postendocytic sorting of seven-transmembrane-spanning G protein-coupled receptors.Dysbindin-1C is required for the survival of hilar mossy cells and the maturation of adult newborn neurons in dentate gyrus.Biogenesis of lysosome-related organelles complex-1 subunit 1 (BLOS1) interacts with sorting nexin 2 and the endosomal sorting complex required for transport-I (ESCRT-I) component TSG101 to mediate the sorting of epidermal growth factor receptor intMeCP2 regulates the synaptic expression of a Dysbindin-BLOC-1 network component in mouse brain and human induced pluripotent stem cell-derived neurons.G protein-coupled receptor (GPCR) signaling via heterotrimeric G proteins from endosomes.Quantitative proteomic and genetic analyses of the schizophrenia susceptibility factor dysbindin identify novel roles of the biogenesis of lysosome-related organelles complex 1.Cell biology of the BLOC-1 complex subunit dysbindin, a schizophrenia susceptibility gene.Effects of endocytosis on receptor-mediated signaling.ALIX Regulates the Ubiquitin-Independent Lysosomal Sorting of the P2Y1 Purinergic Receptor via a YPX3L Motif.Modulating neuromodulation by receptor membrane traffic in the endocytic pathway.ARF6 and GASP-1 are post-endocytic sorting proteins selectively involved in the intracellular trafficking of dopamine D₂ receptors mediated by GRK and PKC in transfected cellsRole of ubiquitination in endocytic trafficking of G-protein-coupled receptors.Gαs regulates the post-endocytic sorting of G protein-coupled receptorsIncreased dysbindin-1B isoform expression in schizophrenia and its propensity in aggresome formation.Molecular Pharmacology of δ-Opioid Receptors.The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the SynapseThe schizophrenia susceptibility gene DTNBP1 modulates AMPAR synaptic transmission and plasticity in the hippocampus of juvenile DBA/2J mice.ESCRT proteins and cell signalling.How ubiquitin functions with ESCRTsThe effect of clozapine on mRNA expression for genes encoding G protein-coupled receptors and the protein components of clathrin-mediated endocytosis.Vacuolar degradation of two integral plasma membrane proteins, AtLRR84A and OsSCAMP1, is cargo ubiquitination-independent and prevacuolar compartment-mediated in plant cells.BLOS2 negatively regulates Notch signaling during neural and hematopoietic stem and progenitor cell development.Neurodevelopmental disease mechanisms, primary cilia, and endosomes converge on the BLOC-1 and BORC complexes.BLOC-1 is required for selective membrane protein trafficking from endosomes to primary cilia.GPCR Retreat 2012: timing is everything.Striatal dopamine release in a schizophrenia mouse model measured by electrochemical amperometry in vivo.Dysbindin-1 modifies signaling and cellular localization of recombinant, human D₃ and D₂ receptors.
P2860
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P2860
Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes
@ast
Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes
@en
Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes
@nl
type
label
Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes
@ast
Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes
@en
Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes
@nl
prefLabel
Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes
@ast
Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes
@en
Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes
@nl
P2860
P3181
P1433
P1476
Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes
@en
P2093
Aaron Marley
P2860
P3181
P356
10.1371/JOURNAL.PONE.0009325
P407
P577
2010-02-19T00:00:00Z