Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development - Wikidata - wikimedia - TriplyDB

Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development

Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development

http://www.wikidata.org/entity/Q28473604

about

GATA6 is a crucial regulator of Shh in the limb bud Gata6-Dependent GLI3 Repressor Function is Essential in Anterior Limb Progenitor Cells for Proper Limb Development Limb anterior-posterior polarity integrates activator and repressor functions of GLI2 as well as GLI3 Msx1 and Msx2 in limb mesenchyme modulate digit number and identity Molecular development of chondrichthyan claspers and the evolution of copulatory organs Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the β-catenin pathway Analysis of transcription factors expressed at the anterior mouse limb bud.Timed deletion of Twist1 in the limb bud reveals age-specific impacts on autopod and zeugopod patterning Evolution of vertebrate appendicular structures: Insight from genetic and palaeontological data.Dual RMCE for efficient re-engineering of mouse mutant alleles.Nipbl and mediator cooperatively regulate gene expression to control limb development.Conserved cis-regulatory regions in a large genomic landscape control SHH and BMP-regulated Gremlin1 expression in mouse limb buds.Hand2 function in second heart field progenitors is essential for cardiogenesis.Axial Hox9 activity establishes the posterior field in the developing forelimb.T396I mutation of mouse Sufu reduces the stability and activity of Gli3 repressor HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme.GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis.Preaxial polydactyly caused by Gli3 haploinsufficiency is rescued by Zic3 loss of function in mice.Anteroposterior Limb Skeletal Patterning Requires the Bifunctional Action of SWI/SNF Chromatin Remodeling Complex in Hedgehog Pathway A shift in anterior-posterior positional information underlies the fin-to-limb evolution.Development of the external genitalia: conserved and divergent mechanisms of appendage patterning.The disruption of a novel limb cis-regulatory element of SHH is associated with autosomal dominant preaxial polydactyly-hypertrichosis T-box3 is a ciliary protein and regulates stability of the Gli3 transcription factor to control digit number.Genetic enhancement of limb defects in a mouse model of Cornelia de Lange syndrome.Transcriptional components of anteroposterior positional information during zebrafish fin regeneration.Hox5 interacts with Plzf to restrict Shh expression in the developing forelimb.A Gli silencer is required for robust repression of gremlin in the vertebrate limb bud.The two domain hypothesis of limb prepattern and its relevance to congenital limb anomalies.Transcriptome analysis of the regenerating tail vs. the scarring limb in lizard reveals pathways leading to successful vs. unsuccessful organ regeneration in amniotes.Loss of Hand2 in a population of Periostin lineage cells results in pronounced bradycardia and neonatal death Cilia-dependent GLI processing in neural crest cells is required for tongue development.The origins, scaling and loss of tetrapod digits.John Saunders' ZPA, Sonic hedgehog and digit identity - How does it really all work?Limb development: a paradigm of gene regulation.GLI3-related polydactyly: a review.Sonic Hedgehog Signaling in Limb Development Gene dosage of the transcription factor Fingerin (bHLHA9) affects digit development and links syndactyly to ectrodactyly.Defective Hand1 phosphoregulation uncovers essential roles for Hand1 in limb morphogenesis.Two Types of Etiological Mutation in the Limb-Specific Enhancer of Shh.Limb-Enhancer Genie: An accessible resource of accurate enhancer predictions in the developing limb.

P2860

Q28538554-8B792436-19C9-45ED-B563-8D757CBD3B63 Q28552221-ABC1A77E-A1E4-4970-86D3-F6C54B16EFFC Q28590845-628B01BD-9058-4985-BC1E-724A2718BC57 Q28592989-DDEBDB72-3B41-4F0D-A99E-0EC2A6FB8B59 Q28649482-25562E25-0713-4EAB-BB8C-26ADAFFF79BF Q28658047-79D43161-4B27-4812-A5B1-F84E565A1ECE Q33632607-71AAFF22-71E1-4E1F-9FA8-74C16791D8B4 Q33707558-2F35C8BD-FFF0-44EC-B68B-4EFB8D017428 Q33825531-B79E9474-473F-40CA-B4D3-3810DBDCA6B6 Q34144198-CD947FB1-E441-41F7-B127-C4FB151BD988 Q34256743-D428CDB9-6F93-45AE-A2FB-B1A2B31F8398 Q34378106-FBBFDBBB-4F4F-4540-9FD3-FB65BA640A2E Q34574679-9B499F3A-F8D9-4E7D-9669-EBBFD2C70E97 Q34720753-18ED59E7-9E8B-42B5-9E11-DB7227CC1E2B Q35168172-9C60777D-9A8B-46EE-8BE5-4CA7BD0C54DC Q35170396-94DCD2EF-445F-49E5-A046-AB0E2C126A66 Q35801438-709A333A-4DC8-4945-B05D-C74891A55CE5 Q35856281-B7E16421-AD88-4F20-B95A-65014A1DD530 Q35950995-20894D5A-2AB0-46C8-85A4-AC13871C5951 Q35961632-AB826E2F-DD77-47CF-9A0A-113DDD04DF9D Q36600149-93339491-71C6-41C9-B421-4767A5B3D192 Q36695886-DFBCDAB0-320B-490D-A3B2-17EB67E5E475 Q36791953-74650885-D966-40EF-A599-0E2BFA65DFDC Q37038926-39326871-CFF2-4022-A00A-8F0A592AB8CA Q37124579-847BE854-958F-4857-A11F-B8D3A5546376 Q37353121-BFA9ED26-CDEB-4657-95BB-62CCE8E467B0 Q37715286-B91A99FB-B58E-46C0-91A9-873173F679C3 Q38742828-AA5C8CFE-C4C8-48F8-9CED-4ABA1C7DDFAC Q38792670-825E53D6-9B25-4454-BBA8-6D50283D3088 Q38809995-39CF5EA6-5D68-4B60-AF99-15C647717803 Q38912342-417D4AD6-266F-460C-A8FC-C482F770CBFE Q39043817-0E40581B-7E86-4932-9F6F-CA3D0855B4FF Q39119924-1D4D7A97-162E-4E83-928A-3E41C2ED0C62 Q39120735-519A642E-1D93-4000-9662-2896CB93E619 Q39146281-1744B853-B7C7-44DA-AAFD-0863FAD5D4F6 Q39178653-910B51EE-3F9F-41E4-99D4-E81BA18B8A71 Q40193998-CB62AABD-F20C-4458-8EAC-7255BC9ED9AE Q41189372-C81FEA4C-B08B-4670-96A5-F2E36E678BA9 Q41384691-54C09EE8-9854-4493-BEE1-E22774439C5B Q41577826-8A75DF20-0D4B-4F96-B406-17A622339ED0

P2860

Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development

http://www.wikidata.org/entity/Q28473604

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Distinct roles of Hand2 in ini ...... of mouse limb bud development

@ast

Distinct roles of Hand2 in ini ...... of mouse limb bud development

@en

Distinct roles of Hand2 in ini ...... of mouse limb bud development

@nl

type

label

Distinct roles of Hand2 in ini ...... of mouse limb bud development

@ast

Distinct roles of Hand2 in ini ...... of mouse limb bud development

@en

Distinct roles of Hand2 in ini ...... of mouse limb bud development

@nl

prefLabel

Distinct roles of Hand2 in ini ...... of mouse limb bud development

@ast

Distinct roles of Hand2 in ini ...... of mouse limb bud development

@en

Distinct roles of Hand2 in ini ...... of mouse limb bud development

@nl

P1433

Q28473604-AB45DB09-0797-4DB9-9E4B-5C30688B1E81

P1476

Q28473604-5C17A091-083C-4E10-A588-5A08B73B48FF

P2093

Q28473604-1F0ECA6B-8B15-4129-A3A9-7CC45793F1BB

Q28473604-35912080-FE33-47D9-AFBD-34CF6E5412D9

Q28473604-3B58D1B8-2F3E-42C0-B2AD-7264B74B2833

Q28473604-59C7CC9D-6371-4F58-A28D-4C2E3F664941

Q28473604-79994DA6-6F33-46C0-B94D-B48F1025EC95

Q28473604-82263511-805D-4878-AD40-7E79CDFC877E

Q28473604-870BA50A-2C45-42B3-B1E6-6BF32A5446CF

P2860

Q28473604-04E7CB9F-91C7-4D6C-AD9E-AEEAEBDF4708

Q28473604-0BEB439C-F712-493F-BF02-1AE23FED67C1

Q28473604-0E2241C9-5688-4125-84B5-BD2B056EE4A4

Q28473604-12972552-320A-4F54-9ABF-4A5CDA7FB374

Q28473604-171C456E-BD11-4FB2-A607-4940FEBA2B3E

Q28473604-1B58CF14-6A45-4B54-BB04-11A21F5442FC

Q28473604-1F16A3B6-69C3-49C0-AE77-2934F5FBC1F2

Q28473604-213A7790-81B3-4777-96C4-29A042606DDA

Q28473604-22B1E1E7-9885-457C-9FD4-1D9A284D1515

Q28473604-26459FCD-A83D-420B-826A-C00DE7D77A58

P304

Q28473604-DEED5407-BF7C-4CFC-A2D1-8739DF563194

P31

Q28473604-F53C8127-ABE4-40EE-8E83-009C33101F38

P3181

Q28473604-05F2B60E-97DE-4631-8F94-AD00439B9B35

P356

Q28473604-F1E7B3C9-C446-4EA8-BA1C-BBF583B2ED1A

P407

Q28473604-66EBCEE9-F106-4B00-A52E-54914C027C51

P433

Q28473604-11D355C5-C636-4B07-AA17-8D7830AA5CFA

P478

Q28473604-CC75F138-665D-4774-AFC2-D39A9F8465EF

P50

Q28473604-58096C28-20F5-483F-A219-332AB1B95832

Q28473604-73FF371F-F250-487B-A59A-B0582AA19BC1

P577

Q28473604-4A9D9286-ACC9-42ED-9684-232FDD498A97

P5875

Q28473604-A3961F30-DADB-456B-86C8-77ACD851897D

P698

Q28473604-42AE55BF-D27A-478E-9BE9-22186BBB1526

P932

Q28473604-AB48543C-88A9-4D5B-8FE3-FB31988DB673

P3181

P356

JOURNAL.PGEN.1000901

P1433

P1476

Distinct roles of Hand2 in ini ...... of mouse limb bud development

@en

P2093

Antonella Galli

http://www.w3.org/2001/XMLSchema#string

Dimitri Robay

http://www.w3.org/2001/XMLSchema#string

Jean-Denis Bénazet

http://www.w3.org/2001/XMLSchema#string

Muhammad Tariq

http://www.w3.org/2001/XMLSchema#string

Renato Paro

http://www.w3.org/2001/XMLSchema#string

Susan Mackem

http://www.w3.org/2001/XMLSchema#string

Xiaozhong Bao

http://www.w3.org/2001/XMLSchema#string

P2860

Deep homology and the origins of evolutionary novelty

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities

Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly

Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function

Functions of FGF signalling from the apical ectodermal ridge in limb development

The basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimer

Phylogenetic conservation of a limb-specific, cis-acting regulator of Sonic hedgehog ( Shh)

P304

e1000901

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

455379

http://www.w3.org/2001/XMLSchema#string

P356

10.1371/JOURNAL.PGEN.1000901

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

6

http://www.w3.org/2001/XMLSchema#string

P50

Marco Osterwalder

P577

2010-04-08T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

43131853

http://www.w3.org/2001/XMLSchema#string

P698

20386744

http://www.w3.org/2001/XMLSchema#string

P932

2851570

http://www.w3.org/2001/XMLSchema#string