Characterization of the Raf kinase inhibitory protein (RKIP) binding pocket: NMR-based screening identifies small-molecule ligands

Characterization of the Raf kinase inhibitory protein (RKIP) binding pocket: NMR-based screening identifies small-molecule ligands

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http://www.wikidata.org/entity/Q28473846
Delineation of Polypharmacology across the Human Structural Kinome Using a Functional Site Interaction Fingerprint ApproachLigand binding study of human PEBP1/RKIP: interaction with nucleotides and Raf-1 peptides evidenced by NMR and mass spectrometry.RKIP structure drives its function: a three-state model for regulation of RKIP.Phosphatidylenthanolamine Binding Protein aka Raf Kinase Inhibitor Protein: A Brief History of Its Discovery and the Remarkable Diversity of Biological Functions.RKIP: much more than Raf kinase inhibitory protein.Novel biomarkers for the prediction of metastasis in colorectal cancer.Interactions of RKIP with inflammatory signaling pathways.Downregulation of PEBP4, a target of miR-34a, sensitizes drug-resistant lung cancer cells.Crosstalks between Raf-kinase inhibitor protein and cancer stem cell transcription factors (Oct4, KLF4, Sox2, Nanog).PEBP4 enhanced HCC827 cell proliferation and invasion ability and inhibited apoptosis.Raf kinase inhibitor protein (RKIP) dimer formation controls its target switch from Raf1 to G protein-coupled receptor kinase (GRK) 2.PEBP4 gene expression and its significance in invasion and metastasis of non-small cell lung cancer.Expression of PEBP4 protein correlates with the invasion and metastasis of colorectal cancer.PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.
P2860

Characterization of the Raf kinase inhibitory protein (RKIP) binding pocket: NMR-based screening identifies small-molecule ligands

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http://www.wikidata.org/entity/Q28473846
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2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Characterization of the Raf ki ...... ntifies small-molecule ligands
@ast
Characterization of the Raf ki ...... ntifies small-molecule ligands
@en
Characterization of the Raf ki ...... ntifies small-molecule ligands
@nl
type
label
Characterization of the Raf ki ...... ntifies small-molecule ligands
@ast
Characterization of the Raf ki ...... ntifies small-molecule ligands
@en
Characterization of the Raf ki ...... ntifies small-molecule ligands
@nl
prefLabel
Characterization of the Raf ki ...... ntifies small-molecule ligands
@ast
Characterization of the Raf ki ...... ntifies small-molecule ligands
@en
Characterization of the Raf ki ...... ntifies small-molecule ligands
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
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P1433
P1476
Characterization of the Raf ki ...... ntifies small-molecule ligands
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0010479
P407
P433
P478
P50
P577
P5875
P698
P921
P932