Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells

Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells

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http://www.wikidata.org/entity/Q28474096
Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos ArylpyrrolesPhenocopy--a strategy to qualify chemical compounds during hit-to-lead and/or lead optimizationRobustness and evolvability in natural chemical resistance: identification of novel systems properties, biochemical mechanisms and regulatory interactions.The synthetic genetic interaction network reveals small molecules that target specific pathways in Sacchromyces cerevisiaeCombined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation.Synthetic lethality: general principles, utility and detection using genetic screens in human cellsFunctional toxicogenomics: mechanism-centered toxicology.Identification of a Mitochondrial DNA Polymerase Affecting Cardiotoxicity of Sunitinib Using a Genome-Wide Screening on S. pombe Deletion Library.A survey of yeast genomic assays for drug and target discovery.Epistasis in genomic and survival data of cancer patients.Intramolecular H-bonding interaction in angular 3-π-EWG substituted imidazo[1,2-a]pyridines contributes to conformational preference.The Budding Yeast "Saccharomyces cerevisiae" as a Drug Discovery Tool to Identify Plant-Derived Natural Products with Anti-Proliferative Properties.
P2860

Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells

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http://www.wikidata.org/entity/Q28474096
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
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2008年論文
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2008年論文
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2008年論文
@zh-hk
2008年論文
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2008年論文
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2008年论文
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name
Chemical-genetic profiling of ...... between yeast and human cells
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Chemical-genetic profiling of ...... between yeast and human cells
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Chemical-genetic profiling of ...... between yeast and human cells
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Chemical-genetic profiling of ...... between yeast and human cells
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Chemical-genetic profiling of ...... between yeast and human cells
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Chemical-genetic profiling of ...... between yeast and human cells
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Chemical-genetic profiling of ...... between yeast and human cells
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Chemical-genetic profiling of ...... between yeast and human cells
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Chemical-genetic profiling of ...... between yeast and human cells
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Chemical-genetic profiling of ...... between yeast and human cells
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10.1371/JOURNAL.PGEN.1000284
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