Optimized hydrophobic interactions and hydrogen bonding at the target-ligand interface leads the pathways of drug-designing
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Molecular determinants of inactivation of the resuscitation promoting factor B from Mycobacterium tuberculosisAgrobacterium mediated transient gene silencing (AMTS) in Stevia rebaudiana: insights into steviol glycoside biosynthesis pathwaySoftware and resources for computational medicinal chemistryFree energetics of rigid body association of ubiquitin binding domains: a biochemical model for binding mediated by hydrophobic interaction.Protein-spanning water networks and implications for prediction of protein-protein interactions mediated through hydrophobic effects.Structural and functional implication of RAP80 ΔGlu81 mutation.Quercetin 3-O-rutinoside mediated inhibition of PBP2a: computational and experimental evidence to its anti-MRSA activity.A computational perspective of molecular interactions through virtual screening, pharmacokinetic and dynamic prediction on ribosome toxin A chain and inhibitors of Ricinus communis.Crystal structures of Mycobacterium tuberculosis GlgE and complexes with non-covalent inhibitors.Molecular insights into cold active polygalacturonase enzyme for its potential application in food processing.Non-covalent interactions involving halogenated derivatives of capecitabine and thymidylate synthase: a computational approach.Molecular characterization and in silico analysis of naturally occurring TEM beta-lactamase variants among pathogenic Enterobacteriaceae infecting Indian patients.Deciphering Structural Stability and Binding Mechanisms of Potential Antagonists with Smoothened Protein.Identification of new potent inhibitors of dengue virus NS3 protease from traditional Chinese medicine database.Studies on Deimmunization of Antileukaemic L-Asparaginase to have Reduced Clinical Immunogenicity--An in silico Approach.Molecular interaction of Survivin and Piperine by computational docking analyses for neuroblastoma targeting.Investigations on Binding Pattern of Kinase Inhibitors with PPARγ: Molecular Docking, Molecular Dynamic Simulations, and Free Energy Calculation Studies.Chemical inhibition of fatty acid synthase: molecular docking analysis and biochemical validation in ocular cancer cells.In silico-based combinatorial pharmacophore modelling and docking studies of GSK-3β and GK inhibitors of Hippophae.Structural insights into the potency of SK channel positive modulators.Danazol has potential to cause PKC translocation, cell cycle dysregulation, and apoptosis in breast cancer cells.Computational and Pharmacological Evaluation of Ferrocene-Based Acyl Ureas and Homoleptic Cadmium Carboxylate Derivatives for Anti-diabetic Potential.Homology modeling and structural comparison of leucine rich repeats of Toll like receptors 1-10 of ruminants.Sulfonamide-Linked Ciprofloxacin, Sulfadiazine and Amantadine Derivatives as a Novel Class of Inhibitors of Jack Bean Urease; Synthesis, Kinetic Mechanism and Molecular Docking.Inhibitory Mechanisms of Human CYPs by Three Alkaloids Isolated from Traditional Chinese Herbs.In silico binding mechanism prediction of benzimidazole based corticotropin releasing factor-1 receptor antagonists by quantitative structure activity relationship, molecular docking and pharmacokinetic parameters calculation.p38 MAPK pathway and its interaction with TRF2 in cisplatin induced chemotherapeutic response in head and neck cancer.Deorphanization of Malonyl CoA:ACP Transacylase Drug Target in Plasmodium falciparum (PfFabD) Using Bacterial Antagonists: A 'Piggyback' Approach for Antimalarial Drug Discovery
P2860
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P2860
Optimized hydrophobic interactions and hydrogen bonding at the target-ligand interface leads the pathways of drug-designing
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Optimized hydrophobic interact ...... the pathways of drug-designing
@ast
Optimized hydrophobic interact ...... the pathways of drug-designing
@en
Optimized hydrophobic interact ...... the pathways of drug-designing
@nl
type
label
Optimized hydrophobic interact ...... the pathways of drug-designing
@ast
Optimized hydrophobic interact ...... the pathways of drug-designing
@en
Optimized hydrophobic interact ...... the pathways of drug-designing
@nl
prefLabel
Optimized hydrophobic interact ...... the pathways of drug-designing
@ast
Optimized hydrophobic interact ...... the pathways of drug-designing
@en
Optimized hydrophobic interact ...... the pathways of drug-designing
@nl
P2093
P2860
P1433
P1476
Optimized hydrophobic interact ...... the pathways of drug-designing
@en
P2093
Akulapalli Sudhakar
Ashley Stanley
Ashok K Varma
Lumbani Yadav
Rohan Patil
Suranjana Das
P2860
P304
P356
10.1371/JOURNAL.PONE.0012029
P407
P577
2010-08-16T00:00:00Z