A structure-based approach for mapping adverse drug reactions to the perturbation of underlying biological pathways
about
Open Babel: An open chemical toolboxSystematic analysis of the associations between adverse drug reactions and pathwaysExploring off-targets and off-systems for adverse drug reactions via chemical-protein interactome--clozapine-induced agranulocytosis as a case studySystematic drug repositioning based on clinical side-effectsAdverse drug reaction prediction using scores produced by large-scale drug-protein target docking on high-performance computing machinesDDI-CPI, a server that predicts drug-drug interactions through implementing the chemical-protein interactome.From laptop to benchtop to bedside: structure-based drug design on protein targets.Fusion of nonclinical and clinical data to predict human drug safety.3D pharmacophoric similarity improves multi adverse drug event identification in pharmacovigilance.Drug Side Effect Profiles as Molecular Descriptors for Predictive Modeling of Target Bioactivity.Systems biology approaches for identifying adverse drug reactions and elucidating their underlying biological mechanisms.Chemical-protein interactome and its application in off-target identification.Drug repositioning for orphan diseases.Relating drug-protein interaction network with drug side effects.Using quantitative systems pharmacology for novel drug discovery.Multivariate Analysis of Side Effects of Drug Molecules Based on Knowledge of Protein Bindings and ProteinProtein Interactions.Relating Essential Proteins to Drug Side-Effects Using Canonical Component Analysis: A Structure-Based Approach.Ensemble-based docking: From hit discovery to metabolism and toxicity predictions.Exploring Landscape of Drug-Target-Pathway-Side Effect Associations.
P2860
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P2860
A structure-based approach for mapping adverse drug reactions to the perturbation of underlying biological pathways
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A structure-based approach for ...... underlying biological pathways
@ast
A structure-based approach for ...... underlying biological pathways
@en
A structure-based approach for ...... underlying biological pathways
@nl
type
label
A structure-based approach for ...... underlying biological pathways
@ast
A structure-based approach for ...... underlying biological pathways
@en
A structure-based approach for ...... underlying biological pathways
@nl
prefLabel
A structure-based approach for ...... underlying biological pathways
@ast
A structure-based approach for ...... underlying biological pathways
@en
A structure-based approach for ...... underlying biological pathways
@nl
P2093
P2860
P1433
P1476
A structure-based approach for ...... underlying biological pathways
@en
P2093
Izhar Wallach
Navdeep Jaitly
Ryan Lilien
P2860
P304
P356
10.1371/JOURNAL.PONE.0012063
P407
P577
2010-08-23T00:00:00Z