In vitro transformation of primary human CD34+ cells by AML fusion oncogenes: early gene expression profiling reveals possible drug target in AML

In vitro transformation of primary human CD34+ cells by AML fusion oncogenes: early gene expression profiling reveals possible drug target in AML

Item
http://www.wikidata.org/entity/Q28475341
The leukemia-specific fusion gene ETV6/RUNX1 perturbs distinct key biological functions primarily by gene repressionComprehensively surveying structure and function of RING domains from Drosophila melanogasterGenome wide analysis of acute myeloid leukemia reveal leukemia specific methylome and subtype specific hypomethylation of repeats.Dynein Light Chain 1 (DYNLT1) Interacts with Normal and Oncogenic Nucleoporins.Amino-terminal enhancer of split (AES) interacts with the oncoprotein NUP98-HOXA9 and enhances its transforming abilityThe role of HOX genes in normal hematopoiesis and acute leukemia.NUP98 Fusion Proteins Interact with the NSL and MLL1 Complexes to Drive Leukemogenesis.Oncogenic fusion proteins expressed in immature hematopoietic cells fail to recapitulate the transcriptional changes observed in human AML.Blocking ETV6/RUNX1-induced MDM2 overexpression by Nutlin-3 reactivates p53 signaling in childhood leukemia.ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia.Effects of threshold on the topology of gene co-expression networks.Murine models based on acute myeloid leukemia-initiating stem cells xenografting.Turning Stem Cells Bad: Generation of Clinically Relevant Models of Human Acute Myeloid Leukemia through Gene Delivery- or Genome Editing-Based Approaches
P2860

In vitro transformation of primary human CD34+ cells by AML fusion oncogenes: early gene expression profiling reveals possible drug target in AML

Item
http://www.wikidata.org/entity/Q28475341
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
In vitro transformation of pri ...... ls possible drug target in AML
@ast
In vitro transformation of pri ...... ls possible drug target in AML
@en
In vitro transformation of pri ...... ls possible drug target in AML
@nl
type
label
In vitro transformation of pri ...... ls possible drug target in AML
@ast
In vitro transformation of pri ...... ls possible drug target in AML
@en
In vitro transformation of pri ...... ls possible drug target in AML
@nl
prefLabel
In vitro transformation of pri ...... ls possible drug target in AML
@ast
In vitro transformation of pri ...... ls possible drug target in AML
@en
In vitro transformation of pri ...... ls possible drug target in AML
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
In vitro transformation of pri ...... ls possible drug target in AML
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0012464
P407
P433
P478
P577
P5875
P698
P932