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Selective killing of cancer cells by Ashwagandha leaf extract and its component Withanone involves ROS signaling

Selective killing of cancer cells by Ashwagandha leaf extract and its component Withanone involves ROS signaling

http://www.wikidata.org/entity/Q28475888

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Protective role of Ashwagandha leaf extract and its component withanone on scopolamine-induced changes in the brain and brain-derived cells Ashwagandha derived withanone targets TPX2-Aurora A complex: computational and experimental evidence to its anticancer activity Differential activities of the two closely related withanolides, Withaferin A and Withanone: bioinformatics and experimental evidences Golden berry-derived 4β-hydroxywithanolide E for selectively killing oral cancer cells by generating ROS, DNA damage, and apoptotic pathways Water extract of Ashwagandha leaves has anticancer activity: identification of an active component and its mechanism of action Combinations of Ashwagandha leaf extracts protect brain-derived cells against oxidative stress and induce differentiation Functional Characterisation of Anticancer Activity in the Aqueous Extract of Helicteres angustifolia L. Roots Novel Methods to Generate Active Ingredients-Enriched Ashwagandha Leaves and Extracts Withaferin-A kills cancer cells with and without telomerase: chemical, computational and experimental evidences.Ashwagandha leaf derived withanone protects normal human cells against the toxicity of methoxyacetic acid, a major industrial metabolite.Evaluation and selection of candidate reference genes for normalization of quantitative RT-PCR in Withania somnifera (L.) Dunal Oxidative cytotoxic agent withaferin A resensitizes temozolomide-resistant glioblastomas via MGMT depletion and induces apoptosis through Akt/mTOR pathway inhibitory modulation.Antiproliferative and Apoptosis Inducing Effects of Non-Polar Fractions from Lawsonia inermis L. in Cervical (HeLa) Cancer Cells.Withaferin A Induces Cell Death Selectively in Androgen-Independent Prostate Cancer Cells but Not in Normal Fibroblast Cells.Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction.Changes in the leaf proteome profile of Withania somnifera (L.) Dunal in response to Alternaria alternata infection Evaluation and Comparison of the In Vitro Cytotoxic Activity of Withania somnifera Methanolic and Ethanolic Extracts against MDA-MB-231 and Vero Cell Lines Cytotoxicity of withaferin A in glioblastomas involves induction of an oxidative stress-mediated heat shock response while altering Akt/mTOR and MAPK signaling pathways.Molecular targets and mechanisms of cancer prevention and treatment by withaferin a, a naturally occurring steroidal lactone.Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells TPX2: of spindle assembly, DNA damage response, and cancer.Biotechnological interventions in Withania somnifera (L.) Dunal.Cinnamomum cassia essential oil and its major constituent cinnamaldehyde induced cell cycle arrest and apoptosis in human oral squamous cell carcinoma HSC-3 cells.Anticancer activity of Ashwagandha against human head and neck cancer cell lines.Natural Withanolides in the Treatment of Chronic Diseases.Exploring the inhibitory activity of Withaferin-A against Pteridine reductase-1 of L. donovani.Withaferin A Induces Oxidative Stress-Mediated Apoptosis and DNA Damage in Oral Cancer Cells.Ashwagandha (Withania somnifera) supercritical CO2 extract derived withanolides mitigates Bisphenol A induced mitochondrial toxicity in HepG2 cells Qing Dai attenuates nonsteroidal anti-inflammatory drug-induced mitochondrial reactive oxygen species in gastrointestinal epithelial cells.First record of the carmine spider mite, Tetranychus urticae, infesting Withania somnifera in India.4β-Hydroxywithanolide E selectively induces oxidative DNA damage for selective killing of oral cancer cells.Effect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patients.Viwithan, a Standardized Withania somnifera Root Extract Induces Apoptosis in Murine Melanoma Cells.Withania somnifera Suppresses Tumor Growth of Intracranial Allograft of Glioma Cells.Analysis of requirements for teaching materials based on the course bioinformatics for plant metabolism

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P2860

Selective killing of cancer cells by Ashwagandha leaf extract and its component Withanone involves ROS signaling

http://www.wikidata.org/entity/Q28475888

description

2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Selective killing of cancer ce ...... thanone involves ROS signaling

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Selective killing of cancer ce ...... thanone involves ROS signaling

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Selective killing of cancer ce ...... thanone involves ROS signaling

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Selective killing of cancer ce ...... thanone involves ROS signaling

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Selective killing of cancer ce ...... thanone involves ROS signaling

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Selective killing of cancer ce ...... thanone involves ROS signaling

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Selective killing of cancer ce ...... thanone involves ROS signaling

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Selective killing of cancer ce ...... thanone involves ROS signaling

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Selective killing of cancer ce ...... thanone involves ROS signaling

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Didik Priyandoko

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Nashi Widodo

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Navjot Shah

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P2860

Novel mutations in LHX3 are associated with hypopituitarism and sensorineural hearing loss

A cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2

Validation of TPX2 as a potential therapeutic target in pancreatic cancer cells.

PANTHER version 6: protein sequence and function evolution data with expanded representation of biological pathways

The GRID: the General Repository for Interaction Datasets

Elimination of hepatitis C virus RNA in infected human hepatocytes by adenovirus-mediated expression of ribozymes

Identification and validation of a gene involved in anchorage-independent cell growth control using a library of randomized hairpin ribozymes

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Applications for protein sequence-function evolution data: mRNA/protein expression analysis and coding SNP scoring tools

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