ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks
about
The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damageHigh-Fidelity Reprogrammed Human IPSCs Have a High Efficacy of DNA Repair and Resemble hESCs in Their MYC Transcriptional SignatureThe role of ATM in the deficiency in nonhomologous end-joining near telomeres in a human cancer cell line.Yeast pol4 promotes tel1-regulated chromosomal translocations.Subtelomeric regions in mammalian cells are deficient in DNA double-strand break repair.Recombination promoted by DNA viruses: phage λ to herpes simplex virus.Trex2 enables spontaneous sister chromatid exchanges without facilitating DNA double-strand break repair.Identification of novel radiosensitizers in a high-throughput, cell-based screen for DSB repair inhibitors.DNA damage response factors from diverse pathways, including DNA crosslink repair, mediate alternative end joining.Correct end use during end joining of multiple chromosomal double strand breaks is influenced by repair protein RAD50, DNA-dependent protein kinase DNA-PKcs, and transcription context.EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.XRCC4/XLF Interaction Is Variably Required for DNA Repair and Is Not Required for Ligase IV StimulationProcessing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks.Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks.Identification of a novel NBN truncating mutation in a family with hereditary prostate cancerMicrohomology directs diverse DNA break repair pathways and chromosomal translocations.The ATM signaling network in development and disease.Concurrent V(D)J recombination and DNA end instability increase interchromosomal trans-rearrangements in ATM-deficient thymocytesContribution of canonical nonhomologous end joining to chromosomal rearrangements is enhanced by ATM kinase deficiency.53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation.Genome damage in induced pluripotent stem cells: assessing the mechanisms and their consequences.Development of safer gene delivery systems to minimize the risk of insertional mutagenesis-related malignancies: a critical issue for the field of gene therapy.Toll-like receptor 4 activity protects against hepatocellular tumorigenesis and progression by regulating expression of DNA repair protein Ku70 in mice.Differences in the recruitment of DNA repair proteins at subtelomeric and interstitial I-SceI endonuclease-induced DNA double-strand breaks.ATM loss leads to synthetic lethality in BRCA1 BRCT mutant mice associated with exacerbated defects in homology-directed repair.
P2860
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P2860
ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
ATM limits incorrect end utili ...... of multiple chromosome breaks
@ast
ATM limits incorrect end utili ...... of multiple chromosome breaks
@en
ATM limits incorrect end utili ...... of multiple chromosome breaks
@nl
type
label
ATM limits incorrect end utili ...... of multiple chromosome breaks
@ast
ATM limits incorrect end utili ...... of multiple chromosome breaks
@en
ATM limits incorrect end utili ...... of multiple chromosome breaks
@nl
prefLabel
ATM limits incorrect end utili ...... of multiple chromosome breaks
@ast
ATM limits incorrect end utili ...... of multiple chromosome breaks
@en
ATM limits incorrect end utili ...... of multiple chromosome breaks
@nl
P2860
P3181
P1433
P1476
ATM limits incorrect end utili ...... of multiple chromosome breaks
@en
P2093
Jeremy M Stark
Nicole Bennardo
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1001194
P407
P577
2010-11-04T00:00:00Z