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Metabolomics to unveil and understand phenotypic diversity between pathogen populations

Metabolomics to unveil and understand phenotypic diversity between pathogen populations

http://www.wikidata.org/entity/Q28476399

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Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance Comparative analysis of the omics technologies used to study antimonial, amphotericin B, and pentamidine resistance in leishmania Functional genomics of trypanosomatids Current challenges in treatment options for visceral leishmaniasis in India: a public health perspective Experimental induction of paromomycin resistance in antimony-resistant strains of L. donovani: outcome dependent on in vitro selection protocol Benznidazole biotransformation and multiple targets in Trypanosoma cruzi revealed by metabolomics A Multiplatform Metabolomic Approach to the Basis of Antimonial Action and Resistance in Leishmania infantum Metabolomic Analyses of Leishmania Reveal Multiple Species Differences and Large Differences in Amino Acid Metabolism In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization.mzMatch-ISO: an R tool for the annotation and relative quantification of isotope-labelled mass spectrometry data LC-MS metabolomics from study design to data-analysis - using a versatile pathogen as a test case.Comparative gene expression analysis throughout the life cycle of Leishmania braziliensis: diversity of expression profiles among clinical isolates.Identification of phospholipid species affected by miltefosine action in Leishmania donovani cultures using LC-ELSD, LC-ESI/MS, and multivariate data analysis.Metabolic variation during development in culture of Leishmania donovani promastigotes.ATG5 is essential for ATG8-dependent autophagy and mitochondrial homeostasis in Leishmania major Large-scale metabolome analysis and quantitative integration with genomics and proteomics data in Mycoplasma pneumoniae.Two birds with one stone: doing metabolomics with your proteomics kit.The newest "omics"--metagenomics and metabolomics--enter the battle against the neglected tropical diseases Combining DI-ESI-MS and NMR datasets for metabolic profiling.NMR Metabolomics Analysis of Parkinson's Disease Metabolic Signature Profiling as a Diagnostic and Prognostic Tool in Pediatric Plasmodium falciparum Malaria Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana.Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii.Elucidation of cellular mechanisms involved in experimental paromomycin resistance in Leishmania donovani.Leishmania antimony resistance: what we know what we can learn from the field.Isotope labeling experiments in metabolomics and fluxomics.LC-MS metabolomics of polar compounds.Drug-resistant microorganisms with a higher fitness--can medicines boost pathogens?Determination of antiprotozoal drug mechanisms by metabolomics approaches.HILIC-MS for metabolomics: An attractive and complementary approach to RPLC-MS.Neglected diseases prioritized in Brazil under the perspective of metabolomics: A review.Beyond the paradigm: Combining mass spectrometry and nuclear magnetic resonance for metabolomics.Experimental resistance to drug combinations in Leishmania donovani: metabolic and phenotypic adaptations.Metabolic adaptations of Leishmania donovani in relation to differentiation, drug resistance, and drug pressure.Evaluating drug resistance in visceral leishmaniasis: the challenges.Macromolecular biosynthetic parameters and metabolic profile in different life stages of Leishmania braziliensis: Amastigotes as a functionally less active stage.Current knowledge of metabolomic approach in infectious fish disease studies.Murine cutaneous leishmaniasis investigated by MALDI mass spectrometry imaging.Cross-resistance of Leishmania infantum isolates to nitric oxide from patients refractory to antimony treatment, and greater tolerance to antileishmanial responses by macrophages.Capillary electrophoresis reveals polyamine metabolism modulation in Leishmania (Leishmania) amazonensis wild type and arginase knockout mutants under arginine starvation.

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Metabolomics to unveil and understand phenotypic diversity between pathogen populations

http://www.wikidata.org/entity/Q28476399

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Metabolomics to unveil and understand phenotypic diversity between pathogen populations

@ast

Metabolomics to unveil and understand phenotypic diversity between pathogen populations

@en

Metabolomics to unveil and understand phenotypic diversity between pathogen populations

@nl

type

label

Metabolomics to unveil and understand phenotypic diversity between pathogen populations

@ast

Metabolomics to unveil and understand phenotypic diversity between pathogen populations

@en

Metabolomics to unveil and understand phenotypic diversity between pathogen populations

@nl

prefLabel

Metabolomics to unveil and understand phenotypic diversity between pathogen populations

@ast

Metabolomics to unveil and understand phenotypic diversity between pathogen populations

@en

Metabolomics to unveil and understand phenotypic diversity between pathogen populations

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PLOS Neglected Tropical Diseases

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Metabolomics to unveil and understand phenotypic diversity between pathogen populations

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David G Watson

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Graham H Coombs

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Jean-Claude Dujardin

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Richard A Scheltema

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Creative Commons Attribution 2.5 Unported

P2860

HMDB: the Human Metabolome Database

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

KEGG: Kyoto Encyclopedia of Genes and Genomes

Cluster analysis and display of genome-wide expression patterns

Failure of pentavalent antimony in visceral leishmaniasis in India: report from the center of the Indian epidemic

Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research

Visceral leishmaniasis: what are the needs for diagnosis, treatment and control?

Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap

Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments

Chemometrics in metabonomics.

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Saskia Decuypere

Rainer Breitling

Kirstyn Brunker

Andris Jankevics

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2010-11-30T00:00:00Z

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49677747

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21152055

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infectious disease

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2994915

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