Using nuclear receptor activity to stratify hepatocarcinogens
about
Advancing human health risk assessment: integrating recent advisory committee recommendationsOrganotypic liver culture models: meeting current challenges in toxicity testing.Building shared experience to advance practical application of pathway-based toxicology: liver toxicity mode-of-action.Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.A metabolomics investigation of non-genotoxic carcinogenicity in the rat.Disruption of embryonic vascular development in predictive toxicology.In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme.Network motifs that recur across species, including gene regulatory and protein-protein interaction networks.Nuclear receptors and nonalcoholic fatty liver disease.Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target.Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assays.Predicting in vivo effect levels for repeat-dose systemic toxicity using chemical, biological, kinetic and study covariates.Uncertainty quantification in ToxCast high throughput screening
P2860
Q27013780-D96D4936-7E7D-40EA-AA7C-950AA30DF560Q36178225-BFC68487-0C73-474A-88FA-5680DADAEF91Q36655325-F2F96BB5-27AD-4B60-8569-8E4FF2DFA9E1Q37121662-AD3CA209-D380-4333-B1D4-F2443C4ADF4CQ37693695-976EDAE5-ECFF-48C0-8260-B63EA2FDC7BEQ37978259-5EA40436-0DFD-40F4-9FAA-D7871A7987A7Q38200703-CDE1434A-5F64-4A38-A201-E69B278388D2Q38213437-916A46E0-487F-43A7-ABA9-92AB201396FBQ38768048-4F0DD7D0-AEFA-4425-A7D7-B3B1B6990944Q39309007-A472A2F8-E63B-4B80-9C46-C6C10DC21C03Q39477437-82883B77-9410-4E76-9465-94CE31CE1054Q50093723-B9550CDC-75E8-43C3-8CCE-1B276F9DDC18Q57555752-E5DB3FF1-C7E0-43B1-89CD-3E124E26D6FC
P2860
Using nuclear receptor activity to stratify hepatocarcinogens
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Using nuclear receptor activity to stratify hepatocarcinogens
@ast
Using nuclear receptor activity to stratify hepatocarcinogens
@en
Using nuclear receptor activity to stratify hepatocarcinogens
@nl
type
label
Using nuclear receptor activity to stratify hepatocarcinogens
@ast
Using nuclear receptor activity to stratify hepatocarcinogens
@en
Using nuclear receptor activity to stratify hepatocarcinogens
@nl
prefLabel
Using nuclear receptor activity to stratify hepatocarcinogens
@ast
Using nuclear receptor activity to stratify hepatocarcinogens
@en
Using nuclear receptor activity to stratify hepatocarcinogens
@nl
P2093
P2860
P50
P1433
P1476
Using nuclear receptor activity to stratify hepatocarcinogens
@en
P2093
David J Dix
Keith Houck
Robert J Kavlock
P2860
P304
P356
10.1371/JOURNAL.PONE.0014584
P407
P577
2011-02-14T00:00:00Z