Pharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in mice - Wikidata - wikimedia - TriplyDB

Pharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in mice

Pharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in mice

http://www.wikidata.org/entity/Q28477318

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TRPM8 Puts the Chill on Prostate Cancer Induction of therapeutic hypothermia by pharmacological modulation of temperature-sensitive TRP channels: theoretical framework and practical considerations TRPM3 in temperature sensing and beyond Permeation, regulation and control of expression of TRP channels by trace metal ions Calcium influx pathways in breast cancer: opportunities for pharmacological intervention VAMP7 regulates constitutive membrane incorporation of the cold-activated channel TRPM8.Skin temperature: its role in thermoregulation Sex differences in mouse Transient Receptor Potential Cation Channel, Subfamily M, Member 8 expressing trigeminal ganglion neurons.Development of TRPM8 Antagonists to Treat Chronic Pain and Migraine.An approach to identify microRNAs involved in neuropathic pain following a peripheral nerve injury.Plant derived aporphinic alkaloid S-(+)-dicentrine induces antinociceptive effect in both acute and chronic inflammatory pain models: evidence for a role of TRPA1 channels Anti-hyperalgesic effects of a novel TRPM8 agonist in neuropathic rats: a comparison with topical menthol.Targeting TRP channels for novel migraine therapeutics.Enhanced behavioral responses to cold stimuli following CGRPα sensory neuron ablation are dependent on TRPM8.The effects of a co-application of menthol and capsaicin on nociceptive behaviors of the rat on the operant orofacial pain assessment device AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia Wu-tou decoction inhibits chronic inflammatory pain in mice: participation of TRPV1 and TRPA1 ion channels.Inhibition of the transient receptor potential melastatin-2 channel causes increased DNA damage and decreased proliferation in breast adenocarcinoma cells The molecular and cellular basis of thermosensation in mammals.Calcium channels and pumps in cancer: changes and consequences.Cellular permeation of large molecules mediated by TRPM8 channels.Meningeal transient receptor potential channel M8 activation causes cutaneous facial and hindpaw allodynia in a preclinical rodent model of headache Characterization of behavioral and neuromuscular junction phenotypes in a novel allelic series of SMA mouse models Pharmacological blockade of the cold receptor TRPM8 attenuates autonomic and behavioral cold defenses and decreases deep body temperature.The molecular and cellular basis of cold sensation.TRPM8 activation attenuates inflammatory responses in mouse models of colitis Inflammatory and neuropathic cold allodynia are selectively mediated by the neurotrophic factor receptor GFRα3 The Emerging Role of Spinal Dynorphin in Chronic Pain: A Therapeutic Perspective A sensory-labeled line for cold: TRPM8-expressing sensory neurons define the cellular basis for cold, cold pain, and cooling-mediated analgesia Artemin, a glial cell line-derived neurotrophic factor family member, induces TRPM8-dependent cold pain.Enhanced insulin clearance in mice lacking TRPM8 channels.The role of trigeminal nasal TRPM8-expressing afferent neurons in the antitussive effects of menthol.Ontogeny of excitatory spinal neurons processing distinct somatic sensory modalities.Shivering and tachycardic responses to external cooling in mice are substantially suppressed by TRPV1 activation but not by TRPM8 inhibition.Targeting Pain-evoking Transient Receptor Potential Channels for the Treatment of Pain.Transient receptor potential channel ankyrin-1 is not a cold sensor for autonomic thermoregulation in rodents.TRPM8 and Migraine TRPM8 in the negative regulation of TNFα expression during cold stress Genes, molecules and patients--emerging topics to guide clinical pain research.Transient receptor potential ion channels in primary sensory neurons as targets for novel analgesics.

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P2860

Pharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in mice

http://www.wikidata.org/entity/Q28477318

description

2011 nî lūn-bûn

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2011 թուականին հրատարակուած գիտական յօդուած

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2011 թվականին հրատարակված գիտական հոդված

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2011年の論文

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Pharmacological blockade of TR ...... nd cold pain responses in mice

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Pharmacological blockade of TR ...... nd cold pain responses in mice

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Pharmacological blockade of TR ...... nd cold pain responses in mice

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Pharmacological blockade of TR ...... nd cold pain responses in mice

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Pharmacological blockade of TR ...... nd cold pain responses in mice

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Pharmacological blockade of TR ...... nd cold pain responses in mice

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prefLabel

Pharmacological blockade of TR ...... nd cold pain responses in mice

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Pharmacological blockade of TR ...... nd cold pain responses in mice

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Pharmacological blockade of TR ...... nd cold pain responses in mice

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Pharmacological blockade of TR ...... nd cold pain responses in mice

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Daniel D McCoy

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David D McKemy

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Radhika Palkar

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Wendy M Knowlton

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P2860

The capsaicin receptor: a heat-activated ion channel in the pain pathway

Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay

Capsazepine block of voltage-activated calcium channels in adult rat dorsal root ganglion neurones in culture

Capsazepine, a vanilloid receptor antagonist, inhibits nicotinic acetylcholine receptors in rat trigeminal ganglia

The discovery of capsazepine, the first competitive antagonist of the sensory neuron excitants capsaicin and resiniferatoxin

Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans

Body-temperature maintenance as the predominant function of the vanilloid receptor TRPV1

Current perspectives on the therapeutic utility of VR1 antagonists

The menthol receptor TRPM8 is the principal detector of environmental cold

TRPM8 is required for cold sensation in mice

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Richard L Daniels

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