Imatinib treatment induces CD5+ B lymphocytes and IgM natural antibodies with anti-leukemic reactivity in patients with chronic myelogenous leukemia
about
Oncogene withdrawal engages the immune system to induce sustained cancer regression.An essential role for the immune system in the mechanism of tumor regression following targeted oncogene inactivation.Imatinib mesylate can help to direct natural immunity toward an anti-leukemic reactivity by acting on the bone marrow microenvironment.A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancerNoncanonical roles of the immune system in eliciting oncogene addictionIncrease of T and B cells and altered BACH2 expression patterns in bone marrow trephines of imatinib-treated patients with chronic myelogenous leukaemia.Combining immunotherapy and targeted therapies in cancer treatment.Overcoming tumor-mediated immunosuppression.
P2860
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P2860
Imatinib treatment induces CD5+ B lymphocytes and IgM natural antibodies with anti-leukemic reactivity in patients with chronic myelogenous leukemia
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Imatinib treatment induces CD5 ...... h chronic myelogenous leukemia
@ast
Imatinib treatment induces CD5 ...... h chronic myelogenous leukemia
@en
Imatinib treatment induces CD5 ...... h chronic myelogenous leukemia
@nl
type
label
Imatinib treatment induces CD5 ...... h chronic myelogenous leukemia
@ast
Imatinib treatment induces CD5 ...... h chronic myelogenous leukemia
@en
Imatinib treatment induces CD5 ...... h chronic myelogenous leukemia
@nl
prefLabel
Imatinib treatment induces CD5 ...... h chronic myelogenous leukemia
@ast
Imatinib treatment induces CD5 ...... h chronic myelogenous leukemia
@en
Imatinib treatment induces CD5 ...... h chronic myelogenous leukemia
@nl
P2093
P2860
P3181
P1433
P1476
Imatinib treatment induces CD5 ...... h chronic myelogenous leukemia
@en
P2093
Ivana Pierri
Marco Gobbi
Silvia Catellani
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0018925
P407
P577
2011-04-18T00:00:00Z