The phosphodiesterase-5 inhibitor vardenafil is a potent inhibitor of ABCB1/P-glycoprotein transporter
about
Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistanceBIRB796, the inhibitor of p38 mitogen-activated protein kinase, enhances the efficacy of chemotherapeutic agents in ABCB1 overexpression cellsbba, a synthetic derivative of 23-hydroxybutulinic acid, reverses multidrug resistance by inhibiting the efflux activity of MRP7 (ABCC10)Recent advances regarding the role of ABC subfamily C member 10 (ABCC10) in the efflux of antitumor drugs.Motesanib (AMG706), a potent multikinase inhibitor, antagonizes multidrug resistance by inhibiting the efflux activity of the ABCB1.Overcoming multiple drug resistance mechanisms in medulloblastoma.PDE5 inhibitors as therapeutics for heart disease, diabetes and cancerPDE5 inhibitors, sildenafil and vardenafil, reverse multidrug resistance by inhibiting the efflux function of multidrug resistance protein 7 (ATP-binding Cassette C10) transporterRepurposing phosphodiesterase-5 inhibitors as chemoadjuvants.ADMET considerations for phosphodiesterase-5 inhibitors.Nobiletin enhances the efficacy of chemotherapeutic agents in ABCB1 overexpression cancer cells.Pharmacodynamics, pharmacokinetics and clinical efficacy of phosphodiesterase-5 inhibitors.Systemic treatment of brain metastases in HER2-positive breast cancer: current status and future directions.Use of different parameters and equations for calculation of IC₅₀ values in efflux assays: potential sources of variability in IC₅₀ determination.Synthesis of 5-oxyquinoline derivatives for reversal of multidrug resistanceDesign of novel β-carboline derivatives with pendant 5-bromothienyl and their evaluation as phosphodiesterase-5 inhibitors.Characterization of efflux transport of the PDE5 inhibitors, vardenafil and sildenafil.Repurposing drugs in oncology (ReDO)-selective PDE5 inhibitors as anti-cancer agents.
P2860
Q26865927-4D732F41-9E70-4DA7-B16B-57706434E6E2Q28485188-8F7C1D8F-1259-4CA9-8930-BC4621A90426Q28533538-A6DB6F02-F302-4472-80E3-990F32B4772FQ33633267-67B4E53D-6C39-41E7-B83A-00CF5C53B983Q34046157-1781A8BC-BC8F-4F5F-BA58-C3BD5BEF40EEQ34500602-61FEE66C-7588-45ED-A654-AE5EE010AE90Q35827798-CD8DA6FB-E7F2-4A10-83AD-70BBE62F5686Q36124056-4E7110CE-7D7F-4832-8FED-3D35C68024C0Q36952021-41EEE6CF-B401-4A0B-B36F-E4C619D1609AQ38024409-047B2990-AEFD-4803-A40A-C3D561E0BF53Q38810143-C4521C7B-E91B-49F8-BFF8-641A6F45B4EEQ38815890-00ACF4EA-9E80-4090-B17D-305CB45FC4ACQ39652258-2AA80601-C7B1-45FF-8250-A7A95AC6CFE1Q41867627-DA843B68-90E6-4FE7-91F6-5C869772390FQ41903734-BC931515-2590-4AAE-8324-232C66CBD67FQ42364586-D5FC139F-33A2-4C3B-8284-5280D97022C2Q42509283-4CBB0093-A0FD-4856-802B-3BCEEFE542E4Q55247585-3D3F504A-BC37-4902-88B7-107C5473BA2B
P2860
The phosphodiesterase-5 inhibitor vardenafil is a potent inhibitor of ABCB1/P-glycoprotein transporter
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The phosphodiesterase-5 inhibi ...... CB1/P-glycoprotein transporter
@ast
The phosphodiesterase-5 inhibi ...... CB1/P-glycoprotein transporter
@en
The phosphodiesterase-5 inhibi ...... CB1/P-glycoprotein transporter
@nl
type
label
The phosphodiesterase-5 inhibi ...... CB1/P-glycoprotein transporter
@ast
The phosphodiesterase-5 inhibi ...... CB1/P-glycoprotein transporter
@en
The phosphodiesterase-5 inhibi ...... CB1/P-glycoprotein transporter
@nl
prefLabel
The phosphodiesterase-5 inhibi ...... CB1/P-glycoprotein transporter
@ast
The phosphodiesterase-5 inhibi ...... CB1/P-glycoprotein transporter
@en
The phosphodiesterase-5 inhibi ...... CB1/P-glycoprotein transporter
@nl
P2093
P2860
P1433
P1476
The phosphodiesterase-5 inhibi ...... CB1/P-glycoprotein transporter
@en
P2093
Amit K Tiwari
Chun-Ling Dai
Dong-Hua Yang
Jeferson W K K Lee
Pei-Rong Ding
Satyakam Singh
Shinobu Ohnuma
Suresh V Ambudkar
Tanaji T Talele
P2860
P304
P356
10.1371/JOURNAL.PONE.0019329
P407
P577
2011-04-28T00:00:00Z