A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease
about
The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease micePotential therapeutic effects of neurotrophins for acute and chronic neurological diseasesDexmedetomidine increases tau phosphorylation under normothermic conditions in vivo and in vitro.A novel Alzheimer's disease drug candidate targeting inflammation and fatty acid metabolism.Back to the future with phenotypic screeningA high content screening approach to identify molecules neuroprotective for photoreceptor cellsThe cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.J-147 a Novel Hydrazide Lead Compound to Treat Neurodegeneration: CeeTox(™) Safety and Genotoxicity Analysis.A comprehensive multiomics approach toward understanding the relationship between aging and dementia.Microglial KCa3.1 Channels as a Potential Therapeutic Target for Alzheimer's DiseaseOxidative stress: a pathogenic mechanism for Niemann-Pick type C disease.A novel natural product inspired scaffold with robust neurotrophic, neurogenic and neuroprotective actionModulation of 5-lipoxygenase in proteotoxicity and Alzheimer's disease.Diosgenin-induced cognitive enhancement in normal mice is mediated by 1,25D₃-MARRS.Selecting for neurogenic potential as an alternative for Alzheimer's disease drug discovery.Modulation of p25 and inflammatory pathways by fisetin maintains cognitive function in Alzheimer's disease transgenic miceDicyanovinyl-substituted J147 analogue inhibits oligomerization and fibrillation of β-amyloid peptides and protects neuronal cells from β-amyloid-induced cytotoxicity.Decreased Neurotrophic Support is Associated with Cognitive Decline in Non-Demented Subjects.Fluorination Effects on NOS Inhibitory Activity of Pyrazoles Related to Curcumin.The mitochondrial ATP synthase is a shared drug target for aging and dementia.Decrease of Amyloid-β Levels by Curcumin Derivative via Modulation of Amyloid-β Protein Precursor Trafficking.Application of Metabolomics in Alzheimer's Disease.A novel curcumin derivative for the treatment of diabetic neuropathy.Transgenic mice with increased astrocyte expression of CCL2 show altered behavioral effects of alcohol.A Potent Multi-functional Neuroprotective Derivative of Tetramethylpyrazine.Efficacy of curcumin for age-associated cognitive decline: a narrative review of preclinical and clinical studies.Computer-Aided Multi-Target Management of Emergent Alzheimer's Disease.The brain-derived neurotrophic factor in neuronal plasticity and neuroregeneration: new pharmacological concepts for old and new drugs.Heat Shock Proteins in Alzheimer's Disease: Role and Targeting
P2860
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P2860
A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease
@ast
A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease
@en
A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease
@nl
type
label
A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease
@ast
A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease
@en
A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease
@nl
prefLabel
A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease
@ast
A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease
@en
A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease
@nl
P2093
P2860
P1433
P1476
A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease
@en
P2093
Amanda Roberts
Chandramouli Chiruta
David Schubert
Kazuho Abe
Marguerite Prior
Pamela Maher
Richard Dargusch
Roland Riek
Tatsuhiro Akaishi
P2860
P304
P356
10.1371/JOURNAL.PONE.0027865
P407
P577
2011-01-01T00:00:00Z