Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling
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The unfolded protein response in multiple sclerosisDrug targets for cell cycle dysregulators in leukemogenesis: in silico docking studiesThe small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alphaPCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.Endoplasmic reticulum stress signaling in mammalian oocytes and embryos: life in balancePERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response.Examination of a second node of translational control in the unfolded protein response.PERK activation mitigates tau pathology in vitro and in vivo.Targeting endoplasmic reticulum signaling pathways in cancer.DNA microarray-based gene expression profiling of estrogenic chemicals.Translational regulator eIF2α in tumor.Smad7 knockdown activates protein kinase RNA-associated eIF2α pathway leading to colon cancer cell death.ER stress and the unfolded protein response in neurodegeneration.Protein kinase R(PKR)-like endoplasmic reticulum kinase (PERK) inhibitors: a patent review (2010-2015).The integrated stress response.The rise of proteostasis promoters.Tetrandrine and caffeine modulated cell cycle and increased glioma cell death via caspase-dependent and caspase-independent apoptosis pathways.The Malat1 long non-coding RNA is upregulated by signalling through the PERK axis of unfolded protein response during flavivirus infection.Ultraviolet Radiation in Wound Care: Sterilization and StimulationEmerging roles of ER stress in the etiology and pathogenesis of Alzheimer's disease.Functional Genomic Analyses of Mendelian and Sporadic Disease Identify Impaired eIF2α Signaling as a Generalizable Mechanism for Dystonia.Proteomic and Metabolomic Analyses of Vanishing White Matter Mouse Astrocytes Reveal Deregulation of ER Functions.Adult mouse eIF2Bε Arg191His astrocytes display a normal integrated stress response in vitro.A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.PERK mediates the IRES-dependent translational activation of mRNAs encoding angiogenic growth factors after ischemic stress.
P2860
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P2860
Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
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2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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name
Mechanism-based screen for G1/ ...... tor of EIF2AK3/PERK signalling
@ast
Mechanism-based screen for G1/ ...... tor of EIF2AK3/PERK signalling
@en
Mechanism-based screen for G1/ ...... tor of EIF2AK3/PERK signalling
@nl
type
label
Mechanism-based screen for G1/ ...... tor of EIF2AK3/PERK signalling
@ast
Mechanism-based screen for G1/ ...... tor of EIF2AK3/PERK signalling
@en
Mechanism-based screen for G1/ ...... tor of EIF2AK3/PERK signalling
@nl
prefLabel
Mechanism-based screen for G1/ ...... tor of EIF2AK3/PERK signalling
@ast
Mechanism-based screen for G1/ ...... tor of EIF2AK3/PERK signalling
@en
Mechanism-based screen for G1/ ...... tor of EIF2AK3/PERK signalling
@nl
P2093
P2860
P1433
P1476
Mechanism-based screen for G1/ ...... tor of EIF2AK3/PERK signalling
@en
P2093
Christelle Soudy
Edward McDonald
Frédéric Elustondo
G Wynne Aherne
Georgia Zoumpoulidou
Georgina Platt
Julian Blagg
Laurent Rigoreau
Mathilde Venet
Michelle D Garrett
P2860
P304
P356
10.1371/JOURNAL.PONE.0028568
P407
P577
2012-01-01T00:00:00Z