Plasma neurofilament heavy chain levels correlate to markers of late stage disease progression and treatment response in SOD1(G93A) mice that model ALS

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2012 nî lūn-bûn

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2012 թուականին հրատարակուած գիտական յօդուած

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2012 թվականին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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Plasma neurofilament heavy cha ...... SOD1(G93A) mice that model ALS

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Plasma neurofilament heavy cha ...... SOD1(G93A) mice that model ALS

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Plasma neurofilament heavy cha ...... SOD1(G93A) mice that model ALS

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Plasma neurofilament heavy cha ...... SOD1(G93A) mice that model ALS

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Plasma neurofilament heavy cha ...... SOD1(G93A) mice that model ALS

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Plasma neurofilament heavy cha ...... SOD1(G93A) mice that model ALS

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Plasma neurofilament heavy cha ...... SOD1(G93A) mice that model ALS

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Plasma neurofilament heavy cha ...... SOD1(G93A) mice that model ALS

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Plasma neurofilament heavy cha ...... SOD1(G93A) mice that model ALS

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P1476

Plasma neurofilament heavy cha ...... SOD1(G93A) mice that model ALS

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P2093

Andrea Malaspina

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Bernadett Kalmar

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Ching-Hua Lu

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James Dick

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Linda Greensmith

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P2860

Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice

Late stage treatment with arimoclomol delays disease progression and prevents protein aggregation in the SOD1 mouse model of ALS

A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

SHIRPA, a protocol for behavioral assessment: validation for longitudinal study of neurological dysfunction in mice.

The application of biomarkers in clinical trials for motor neuron disease

Patients with amyotrophic lateral sclerosis and other neurodegenerative diseases have increased levels of neurofilament protein in CSF.

Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment.

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e40998

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scholarly article

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5034195

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10.1371/JOURNAL.PONE.0040998

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English

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Axel Petzold

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2012-01-01T00:00:00Z

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229427894

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22815892

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P921

amyotrophic lateral sclerosis

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3397981

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