Inhibition of E2F1/CDK1 pathway attenuates neuronal apoptosis in vitro and confers neuroprotection after spinal cord injury in vivo
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The role of pharmacotherapy in modifying the neurological status of patients with spinal and spinal cord injuriesRegulation of Bim in Health and DiseaseE2F4 Promotes Neuronal Regeneration and Functional Recovery after Spinal Cord Injury in ZebrafishGene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration.What's New in Traumatic Brain Injury: Update on Tracking, Monitoring and TreatmentIsolated spinal cord contusion in rats induces chronic brain neuroinflammation, neurodegeneration, and cognitive impairment. Involvement of cell cycle activationSpinal cord injury causes brain inflammation associated with cognitive and affective changes: role of cell cycle pathways.Pharmacokinetics and biodistribution of the cyclin-dependent kinase inhibitor -CR8- in mice.Altered Mitochondrial Dynamics Contributes to Propofol-induced Cell Death in Human Stem Cell-derived Neurons.An Up-regulation of IRF-1 After a Spinal Cord Injury: Implications for Neuronal Apoptosis.HEDGEHOG/GLI-E2F1 axis modulates iASPP expression and function and regulates melanoma cell growth.Ablation of the transcription factors E2F1-2 limits neuroinflammation and associated neurological deficits after contusive spinal cord injuryThe feasibility of in vivo imaging of infiltrating blood cells for predicting the functional prognosis after spinal cord injury.Cell cycle inhibition limits development and maintenance of neuropathic pain following spinal cord injury.Cell cycle activation contributes to increased neuronal activity in the posterior thalamic nucleus and associated chronic hyperesthesia after rat spinal cord contusionTrkB.T1 contributes to neuropathic pain after spinal cord injury through regulation of cell cycle pathways.Cyclin-dependent kinases regulate apoptosis of intestinal epithelial cells.CR8, a novel inhibitor of CDK, limits microglial activation, astrocytosis, neuronal loss, and neurologic dysfunction after experimental traumatic brain injury.Spatiotemporal pattern of TRAF3 expression after rat spinal cord injury.The Expression of VHL (Von Hippel-Lindau) After Traumatic Spinal Cord Injury and Its Role in Neuronal Apoptosis.Expression of RBMX after spinal cord injury in rats.Decreased GFAP expression and improved functional recovery in contused spinal cord of rats following valproic acid therapy.Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death.Complement After Trauma: Suturing Innate and Adaptive ImmunityComparing effects of CDK inhibition and E2F1/2 ablation on neuronal cell death pathways in vitro and after traumatic brain injury
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P2860
Inhibition of E2F1/CDK1 pathway attenuates neuronal apoptosis in vitro and confers neuroprotection after spinal cord injury in vivo
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Inhibition of E2F1/CDK1 pathwa ...... ter spinal cord injury in vivo
@ast
Inhibition of E2F1/CDK1 pathwa ...... ter spinal cord injury in vivo
@en
Inhibition of E2F1/CDK1 pathwa ...... ter spinal cord injury in vivo
@nl
type
label
Inhibition of E2F1/CDK1 pathwa ...... ter spinal cord injury in vivo
@ast
Inhibition of E2F1/CDK1 pathwa ...... ter spinal cord injury in vivo
@en
Inhibition of E2F1/CDK1 pathwa ...... ter spinal cord injury in vivo
@nl
prefLabel
Inhibition of E2F1/CDK1 pathwa ...... ter spinal cord injury in vivo
@ast
Inhibition of E2F1/CDK1 pathwa ...... ter spinal cord injury in vivo
@en
Inhibition of E2F1/CDK1 pathwa ...... ter spinal cord injury in vivo
@nl
P2093
P2860
P3181
P1433
P1476
Inhibition of E2F1/CDK1 pathwa ...... ter spinal cord injury in vivo
@en
P2093
Alan I Faden
Boris Sabirzhanov
Chunshu Piao
Giorgi Kharebava
Junfang Wu
Kelsey Guanciale
Marie Hanscom
Michael Dinizo
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0042129
P407
P577
2012-01-01T00:00:00Z