Chemical mechanism of UDP-galactopyranose mutase from Trypanosoma cruzi: a potential drug target against Chagas' disease
about
Targeting UDP-galactopyranose mutases from eukaryotic human pathogensIdentification of the NAD(P)H Binding Site of Eukaryotic UDP-Galactopyranose MutaseCrystal Structures of Trypanosoma cruzi UDP-Galactopyranose Mutase Implicate Flexibility of the Histidine Loop in Enzyme ActivationContributions of unique active site residues of eukaryotic UDP-galactopyranose mutases to substrate recognition and active site dynamics.QM/MM molecular dynamics study of the galactopyranose → galactofuranose reaction catalysed by Trypanosoma cruzi UDP-galactopyranose mutase.Noncanonical reactions of flavoenzymes.In Crystallo Capture of a Covalent Intermediate in the UDP-Galactopyranose Mutase Reaction.UDP-galactopyranose mutase in nematodes.Structure, mechanism, and dynamics of UDP-galactopyranose mutase.Substrate-dependent dynamics of UDP-galactopyranose mutase: Implications for drug design.UDP-galactopyranose mutases from Leishmania species that cause visceral and cutaneous leishmaniasis.UDP-galactopyranose mutase, a potential drug target against human pathogenic nematode Brugia malayi.Multiple functionalities of reduced flavin in the non-redox reaction catalyzed by UDP-galactopyranose mutase.Identification of Aspergillus fumigatus UDP-Galactopyranose Mutase Inhibitors.Comparative genome analysis of Campylobacter fetus subspecies revealed horizontally acquired genetic elements important for virulence and niche specificity.Flavin-N5 Covalent Intermediate in the Non-redox Dehalogenation Reaction Catalyzed by an Atypical Flavoenzyme.Identification of novel inhibitors against UDP-galactopyranose mutase to combat leishmaniasis.Tetrafluorination of sugars as strategy for enhancing protein-carbohydrate affinity: application to UDP-Galp mutase inhibition.
P2860
Q26862107-94ED7A8C-E2F6-4ADD-987D-3421BF455D5FQ27674233-24F20237-9FD9-42B3-A01B-9ABBB8EA7DE0Q27679366-C0366821-61D4-46EF-9E89-9E88275071EDQ34731559-E531C3FA-7CC3-4931-B8B6-75E6B65154A6Q35315473-141E2ABC-E837-405C-843C-5D51D808D0BAQ36432446-FF7AC81F-755B-463E-A34A-D92A3AF518FFQ36761390-9ADE345E-A04E-464F-8B52-20BB2B3B3D44Q37189388-D86BC596-7C71-4075-9DF7-EEB103F97E30Q37624622-7BE83AEA-7CA1-4EF0-AF5A-B99F881A1B85Q38912866-9FBC7B3C-9EFE-4D77-9054-F2536CF404FEQ39007567-9794E00D-D4C1-42D6-A190-24DEBA01DCE3Q39254459-8DAC6E28-97D2-4616-9B52-F644E986C03AQ39399288-1CB83978-E556-4403-AEB8-E54C0FA627F0Q40061592-E518BC97-080D-48AB-AAAE-592141F14E96Q41863088-7F35E249-88DA-4999-80A9-CA433ABCBCF7Q45072307-B5BE9D68-55F4-40C2-94C2-B0D441F0B7D2Q47616970-162EF6E3-E90F-45E0-8254-0B6492180543Q51768513-D5848E4D-BE6D-4AE1-9417-FA696EB3A288
P2860
Chemical mechanism of UDP-galactopyranose mutase from Trypanosoma cruzi: a potential drug target against Chagas' disease
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Chemical mechanism of UDP-gala ...... target against Chagas' disease
@ast
Chemical mechanism of UDP-gala ...... target against Chagas' disease
@en
Chemical mechanism of UDP-gala ...... target against Chagas' disease
@nl
type
label
Chemical mechanism of UDP-gala ...... target against Chagas' disease
@ast
Chemical mechanism of UDP-gala ...... target against Chagas' disease
@en
Chemical mechanism of UDP-gala ...... target against Chagas' disease
@nl
prefLabel
Chemical mechanism of UDP-gala ...... target against Chagas' disease
@ast
Chemical mechanism of UDP-gala ...... target against Chagas' disease
@en
Chemical mechanism of UDP-gala ...... target against Chagas' disease
@nl
P2093
P2860
P1433
P1476
Chemical mechanism of UDP-gala ...... target against Chagas' disease
@en
P2093
Karina Kizjakina
Michelle Oppenheimer
Pablo Sobrado
P2860
P304
P356
10.1371/JOURNAL.PONE.0032918
P407
P577
2012-01-01T00:00:00Z