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Global assessment of genomic regions required for growth in Mycobacterium tuberculosis

Global assessment of genomic regions required for growth in Mycobacterium tuberculosis

http://www.wikidata.org/entity/Q28484097

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Distributive conjugal transfer in mycobacteria generates progeny with meiotic-like genome-wide mosaicism, allowing mapping of a mating identity locus A multi-level multi-scale approach to study essential genes in Mycobacterium tuberculosis Translating genomics research into control of tuberculosis: lessons learned and future prospects ARTIST: high-resolution genome-wide assessment of fitness using transposon-insertion sequencing Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria Characterization of the proline-utilization pathway in Mycobacterium tuberculosis through structural and functional studies Mycobacterial genes essential for the pathogen's survival in the host A Methyl 4-Oxo-4-phenylbut-2-enoate with in Vivo Activity against MRSA that Inhibits MenB in the Bacterial Menaquinone Biosynthesis Pathway Surface hydrolysis of sphingomyelin by the outer membrane protein Rv0888 supports replication of Mycobacterium tuberculosis in macrophages Induced ectopic expression of HigB toxin in Mycobacterium tuberculosis results in growth inhibition, reduced abundance of a subset of mRNAs and cleavage of tmRNA Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection Succinate dehydrogenase is the regulator of respiration in Mycobacterium tuberculosis Mycobacterial Metabolic Syndrome: LprG and Rv1410 Regulate Triacylglyceride Levels, Growth Rate and Virulence in Mycobacterium tuberculosis Mycobacterium tuberculosis Thioredoxin Reductase Is Essential for Thiol Redox Homeostasis but Plays a Minor Role in Antioxidant Defense DEG 10, an update of the database of essential genes that includes both protein-coding genes and noncoding genomic elements A Genome-Wide Screen Reveals that the Vibrio cholerae Phosphoenolpyruvate Phosphotransferase System Modulates Virulence Gene Expression Metabolic Perspectives on Persistence High-resolution definition of the Vibrio cholerae essential gene set with hidden Markov model-based analyses of transposon-insertion sequencing data A Hidden Markov Model for identifying essential and growth-defect regions in bacterial genomes from transposon insertion sequencing data.A zero-inflated Poisson model for insertion tolerance analysis of genes based on Tn-seq data.The highly conserved bacterial RNase YbeY is essential in Vibrio cholerae, playing a critical role in virulence, stress regulation, and RNA processing Mycobacterial Esx-3 requires multiple components for iron acquisition.Disruption of Mycobacterium avium subsp. paratuberculosis-specific genes impairs in vivo fitness Statistical analysis of genetic interactions in Tn-Seq data.Small RNAs in mycobacteria: an unfolding story.Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis.Genome-wide mutant fitness profiling identifies nutritional requirements for optimal growth of Yersinia pestis in deep tissue.Genes contributing to Staphylococcus aureus fitness in abscess- and infection-related ecologies.Approaches to querying bacterial genomes with transposon-insertion sequencing Transposon insertion sequencing: a new tool for systems-level analysis of microorganisms.Energetics of Respiration and Oxidative Phosphorylation in Mycobacteria.The cell envelope glycoconjugates of Mycobacterium tuberculosis Non-coding RNA regulation in pathogenic bacteria located inside eukaryotic cells.Bayesian analysis of gene essentiality based on sequencing of transposon insertion libraries.Lipoproteins of slow-growing Mycobacteria carry three fatty acids and are N-acylated by apolipoprotein N-acyltransferase BCG_2070c Systems biology-based identification of Mycobacterium tuberculosis persistence genes in mouse lungs Post-translational regulation via Clp protease is critical for survival of Mycobacterium tuberculosis.A novel antimycobacterial compound acts as an intracellular iron chelator.

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Global assessment of genomic regions required for growth in Mycobacterium tuberculosis

http://www.wikidata.org/entity/Q28484097

description

2012 nî lūn-bûn

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2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Global assessment of genomic regions required for growth in Mycobacterium tuberculosis

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Global assessment of genomic regions required for growth in Mycobacterium tuberculosis

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Global assessment of genomic regions required for growth in Mycobacterium tuberculosis

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type

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Global assessment of genomic regions required for growth in Mycobacterium tuberculosis

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Global assessment of genomic regions required for growth in Mycobacterium tuberculosis

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Global assessment of genomic regions required for growth in Mycobacterium tuberculosis

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prefLabel

Global assessment of genomic regions required for growth in Mycobacterium tuberculosis

@ast

Global assessment of genomic regions required for growth in Mycobacterium tuberculosis

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Global assessment of genomic regions required for growth in Mycobacterium tuberculosis

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JOURNAL.PPAT.1002946

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Global assessment of genomic regions required for growth in Mycobacterium tuberculosis

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Christopher M Sassetti

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James C Sacchettini

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Jarukit E Long

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Thomas R Ioerger

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Yanjia J Zhang

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P2860

High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

Comprehensive identification of conditionally essential genes in mycobacteria

The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system

Ribonuclease P: an enzyme with an essential RNA component

The CGView Server: a comparative genomics tool for circular genomes

Identification of small RNAs in Mycobacterium tuberculosis

A Phosphorylated Pseudokinase Complex Controls Cell Wall Synthesis in Mycobacteria

Genes required for mycobacterial growth defined by high density mutagenesis

Sequence-based analysis uncovers an abundance of non-coding RNA in the total transcriptome of Mycobacterium tuberculosis

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10.1371/JOURNAL.PPAT.1002946

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9

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Curtis Huttenhower

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Mycobacterium tuberculosis

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