Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice
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Tau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer's DiseaseUpdate on Disease-Modifying/Preventive Therapies in Alzheimer’s DiseaseRapamycin attenuates the progression of tau pathology in P301S tau transgenic miceIntrinsic Tau Acetylation Is Coupled to Auto-Proteolytic Tau FragmentationPreventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau.Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathiesMethylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicitySpecific calpain inhibition by calpastatin prevents tauopathy and neurodegeneration and restores normal lifespan in tau P301L miceMethylene blue modulates β-secretase, reverses cerebral amyloidosis, and improves cognition in transgenic mice.PE859, a novel tau aggregation inhibitor, reduces aggregated tau and prevents onset and progression of neural dysfunction in vivo.Effects of oxidized and reduced forms of methylthioninium in two transgenic mouse tauopathy models.Nontoxic singlet oxygen generator as a therapeutic candidate for treating tauopathies.Swa2, the yeast homolog of mammalian auxilin, is specifically required for the propagation of the prion variant [URE3-1].Alternative mitochondrial electron transfer for the treatment of neurodegenerative diseases and cancers: Methylene blue connects the dots.Perspectives on the Tertiary Prevention Strategy for Alzheimer's Disease.Inhibition of Both Hsp70 Activity and Tau Aggregation in Vitro Best Predicts Tau Lowering Activity of Small Molecules.A Dual Pathogenic Mechanism Links Tau Acetylation to Sporadic Tauopathy.Progranulin haploinsufficiency reduces amyloid beta deposition in Alzheimer's disease model mice.Tau-directed approaches for the treatment of Alzheimer's disease: focus on leuco-methylthioninium.Methylene Blue Inhibits Caspases by Oxidation of the Catalytic Cysteine.Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy.Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening.From Mitochondrial Function to Neuroprotection-an Emerging Role for Methylene Blue.Tau aggregation inhibitors: the future of Alzheimer's pharmacotherapy?
P2860
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P2860
Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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name
Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice
@ast
Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice
@en
Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice
@nl
type
label
Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice
@ast
Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice
@en
Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice
@nl
prefLabel
Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice
@ast
Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice
@en
Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice
@nl
P2093
P2860
P3181
P1433
P1476
Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice
@en
P2093
Haruhiko Akiyama
Makiko Yamashita
Masami Masuda-Suzukake
Masato Hasegawa
Tetsuaki Arai
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0052389
P407
P577
2012-01-01T00:00:00Z