The co-chaperone Hch1 regulates Hsp90 function differently than its homologue Aha1 and confers sensitivity to yeast to the Hsp90 inhibitor NVP-AUY922
about
Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug designAn Hsp90 co-chaperone protein in yeast is functionally replaced by site-specific posttranslational modification in humansExpression of three topologically distinct membrane proteins elicits unique stress response pathways in the yeast Saccharomyces cerevisiaeInteraction of heat shock protein 90 and the co-chaperone Cpr6 with Ura2, a bifunctional enzyme required for pyrimidine biosynthesisp53 protein regulates Hsp90 ATPase activity and thereby Wnt signaling by modulating Aha1 expressionContributions of co-chaperones and post-translational modifications towards Hsp90 drug sensitivity.The Mechanism of Hsp90 ATPase Stimulation by Aha1Evidence for Hsp90 Co-chaperones in Regulating Hsp90 Function and Promoting Client Protein Folding.Mutation of essential Hsp90 co-chaperones SGT1 or CNS1 renders yeast hypersensitive to overexpression of other co-chaperones.
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P2860
The co-chaperone Hch1 regulates Hsp90 function differently than its homologue Aha1 and confers sensitivity to yeast to the Hsp90 inhibitor NVP-AUY922
description
2012 nî lūn-bûn
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2012 թուականին հրատարակուած գիտական յօդուած
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2012 թվականին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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name
The co-chaperone Hch1 regulate ...... the Hsp90 inhibitor NVP-AUY922
@ast
The co-chaperone Hch1 regulate ...... the Hsp90 inhibitor NVP-AUY922
@en
The co-chaperone Hch1 regulate ...... the Hsp90 inhibitor NVP-AUY922
@nl
type
label
The co-chaperone Hch1 regulate ...... the Hsp90 inhibitor NVP-AUY922
@ast
The co-chaperone Hch1 regulate ...... the Hsp90 inhibitor NVP-AUY922
@en
The co-chaperone Hch1 regulate ...... the Hsp90 inhibitor NVP-AUY922
@nl
prefLabel
The co-chaperone Hch1 regulate ...... the Hsp90 inhibitor NVP-AUY922
@ast
The co-chaperone Hch1 regulate ...... the Hsp90 inhibitor NVP-AUY922
@en
The co-chaperone Hch1 regulate ...... the Hsp90 inhibitor NVP-AUY922
@nl
P2093
P2860
P3181
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The co-chaperone Hch1 regulate ...... the Hsp90 inhibitor NVP-AUY922
@en
P2093
Annemarie Wolmarans
BaoChan Mai
Heather Armstrong
Paul LaPointe
Rebecca Mercier
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P304
P3181
P356
10.1371/JOURNAL.PONE.0049322
P407
P577
2012-01-01T00:00:00Z