Drug target prediction and repositioning using an integrated network-based approach
about
Prediction of Druggable Proteins Using Machine Learning and Systems Biology: A Mini-ReviewFundamentals of protein interaction network mappingMethods for biological data integration: perspectives and challengesNetwork-based approaches in drug discovery and early developmentApplications of systems approaches in the study of rheumatic diseases.Open-source approaches for the repurposing of existing or failed candidate drugs: learning from and applying the lessons across diseasesLigand-target prediction by structural network biology using nAnnoLyzeGenerating Gene Ontology-Disease Inferences to Explore Mechanisms of Human Disease at the Comparative Toxicogenomics DatabaseA Multilayer Network Approach for Guiding Drug Repositioning in Neglected DiseasesDrug Repositioning through Systematic Mining of Gene Coexpression Networks in CancerA Network-Based Data Integration Approach to Support Drug Repurposing and Multi-Target Therapies in Triple Negative Breast CancerA Systematic Framework for Drug Repositioning from Integrated Omics and Drug Phenotype Profiles Using Pathway-Drug NetworkRare and common epilepsies converge on a shared gene regulatory network providing opportunities for novel antiepileptic drug discovery.Identification of novel therapeutics for complex diseases from genome-wide association data.SuperPred: update on drug classification and target predictionDrug repositioning by integrating target information through a heterogeneous network model.The effect of network biology on drug toxicology.CellFateScout - a bioinformatics tool for elucidating small molecule signaling pathways that drive cells in a specific directionA three step network based approach (TSNBA) to finding disease molecular signature and key regulators: a case study of IL-1 and TNF-alpha stimulated inflammation.A systems biology investigation of neurodegenerative dementia reveals a pivotal role of autophagy.Network-based inference methods for drug repositioningPrediction of drugs having opposite effects on disease genes in a directed network.Identification potential biomarkers in pulmonary tuberculosis and latent infection based on bioinformatics analysis.Back to the future: Alzheimer's disease heterogeneity revisited.Connecting the dots: applications of network medicine in pharmacology and disease.Medications development for substance-use disorders: contextual influences (dis)incentivizing pharmaceutical-industry positioning.Computer-aided drug discovery.Drug-target interaction prediction: databases, web servers and computational models.In silico prediction of novel therapeutic targets using gene-disease association data.Knowledge-guided gene prioritization reveals new insights into the mechanisms of chemoresistance.Network-based Approaches in Pharmacology.Drug target prioritization by perturbed gene expression and network information.Network-assisted prediction of potential drugs for addiction.A protein network descriptor server and its use in studying protein, disease, metabolic and drug targeted networks.Novel drug target identification for the treatment of dementia using multi-relational association mining.An integrated structure- and system-based framework to identify new targets of metabolites and known drugs.Causal Network Models for Predicting Compound Targets and Driving Pathways in Cancer.Predicting drug-disease interactions by semi-supervised graph cut algorithm and three-layer data integration.gene2drug: a Computational Tool for Pathway-based Rational Drug Repositioning.Network perturbation analysis of gene transcriptional profiles reveals protein targets and mechanism of action of drugs and influenza A viral infection.
P2860
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P2860
Drug target prediction and repositioning using an integrated network-based approach
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Drug target prediction and repositioning using an integrated network-based approach
@ast
Drug target prediction and repositioning using an integrated network-based approach
@en
Drug target prediction and repositioning using an integrated network-based approach
@nl
type
label
Drug target prediction and repositioning using an integrated network-based approach
@ast
Drug target prediction and repositioning using an integrated network-based approach
@en
Drug target prediction and repositioning using an integrated network-based approach
@nl
prefLabel
Drug target prediction and repositioning using an integrated network-based approach
@ast
Drug target prediction and repositioning using an integrated network-based approach
@en
Drug target prediction and repositioning using an integrated network-based approach
@nl
P2093
P2860
P3181
P1433
P1476
Drug target prediction and repositioning using an integrated network-based approach
@en
P2093
Alexander Ivliev
Marina Bessarabova
Olga Pustovalova
Svetlana Bureeva
Yuri Nikolsky
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0060618
P407
P577
2013-01-01T00:00:00Z