The mabA gene from the inhA operon of Mycobacterium tuberculosis encodes a 3-ketoacyl reductase that fails to confer isoniazid resistance
about
Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthasesThe Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III activity is inhibited by phosphorylation on a single threonine residueDirected evolution approach to a structural genomics project: Rv2002 from Mycobacterium tuberculosisPhosphorylation of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA regulates mycolic acid biosynthesisThe essential mycobacterial genes, fabG1 and fabG4, encode 3-oxoacyl-thioester reductases that are functional in yeast mitochondrial fatty acid synthase type 2Mycolic acid biosynthesis and enzymic characterization of the beta-ketoacyl-ACP synthase A-condensing enzyme from Mycobacterium tuberculosisEfflux pump gene expression in multidrug-resistant Mycobacterium tuberculosis clinical isolatesSynthesis and biological evaluation of NAS-21 and NAS-91 analogues as potential inhibitors of the mycobacterial FAS-II dehydratase enzyme Rv0636.Molecular characterization of isoniazid-resistant Mycobacterium tuberculosis isolates collected in AustraliaThe Mycobacterium tuberculosis FAS-II dehydratases and methyltransferases define the specificity of the mycolic acid elongation complexes.Role of Serine140 in the mode of action of Mycobacterium tuberculosis β-ketoacyl-ACP Reductase (MabA)Detection of multidrug resistance in Mycobacterium tuberculosisComparative cell wall core biosynthesis in the mycolated pathogens, Mycobacterium tuberculosis and Corynebacterium diphtheriae.Functional complementation of the essential gene fabG1 of Mycobacterium tuberculosis by Mycobacterium smegmatis fabG but not Escherichia coli fabGA predicted operon map for Mycobacterium tuberculosis.Implications of phase variation of a gene (pgtA) encoding a pilin galactosyl transferase in gonococcal pathogenesis.Recycling and refurbishing old antitubercular drugs: the encouraging case of inhibitors of mycolic acid biosynthesis.Conditional depletion of KasA, a key enzyme of mycolic acid biosynthesis, leads to mycobacterial cell lysis.Single nucleotide polymorphisms in genes associated with isoniazid resistance in Mycobacterium tuberculosis.In vitro inhibition of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA by isoniazid.Use of genotype MTBDR assay for molecular detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis clinical strains isolated in Italy.Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis.Evolution of Phenotypic and Molecular Drug Susceptibility Testing.
P2860
Q21562402-E5270A35-A08E-470F-BB97-27FF9162DB2DQ24647120-3594B47F-6E12-4097-B19E-DE9C0BB04632Q27640298-1F985389-7D0C-4076-87C7-CE9321CF8568Q28486676-7AC22814-FB9F-4452-AAA8-E91A4EF2D489Q28487203-6A886E69-9B80-434E-BBEA-15166D39C89FQ28487484-FC8CF2FE-F942-48D7-9A14-B61AC5B70C50Q28543543-7B8040DC-C24C-45A6-9DAC-4F67198AF9ECQ30844885-3BC84BB0-0514-4BC1-A3A7-4045A6724687Q34077090-157D2E80-A5C7-44A9-A1D9-7095A07F69BAQ34117721-66BFD707-20ED-434F-8E5F-625CA5BE2B5FQ34420138-46AACD39-9E94-4139-ACE4-A883B3B22FD0Q35690316-6D2B641D-3C7F-4D09-851C-2CF607C3437AQ35756648-DEEE15C0-F0BC-4962-9260-E0BEE0102984Q35879195-5E1AC8FE-7B11-469C-A480-E03E6BFDC9D9Q35990883-563285A9-7222-49C1-8E87-787D3F0972FDQ36370821-D50D64F0-6C4B-40CA-93A8-63698E8FA45DQ38097123-5399668B-024D-45D8-993D-A24E90602906Q39614772-98F444AD-84B8-49DD-8B20-D332E7EFD90DQ39743333-299A0DB0-0DD2-418A-87CE-28807C97ED88Q40410540-DBF817C7-7FD4-48F4-912C-35ADF477A759Q41481828-B43D7B4E-EF57-4D7E-BDC2-2410C2A017CAQ44198145-0ADCBBC3-FC0F-4504-B092-872DD4BE809FQ47632774-FC90440B-47A8-47CD-9634-45ECC5814F52
P2860
The mabA gene from the inhA operon of Mycobacterium tuberculosis encodes a 3-ketoacyl reductase that fails to confer isoniazid resistance
description
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im Oktober 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/10/01)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/10/01)
@nl
наукова стаття, опублікована в жовтні 1998
@uk
مقالة علمية (نشرت في أكتوبر 1998)
@ar
name
The mabA gene from the inhA op ...... to confer isoniazid resistance
@ast
The mabA gene from the inhA op ...... to confer isoniazid resistance
@en
The mabA gene from the inhA op ...... to confer isoniazid resistance
@nl
type
label
The mabA gene from the inhA op ...... to confer isoniazid resistance
@ast
The mabA gene from the inhA op ...... to confer isoniazid resistance
@en
The mabA gene from the inhA op ...... to confer isoniazid resistance
@nl
prefLabel
The mabA gene from the inhA op ...... to confer isoniazid resistance
@ast
The mabA gene from the inhA op ...... to confer isoniazid resistance
@en
The mabA gene from the inhA op ...... to confer isoniazid resistance
@nl
P2093
P1433
P1476
The mabA gene from the inhA op ...... to confer isoniazid resistance
@en
P2093
A. Banerjee
J. C. Sacchettini
M. Sugantino
W. R. Jacobs
P304
P356
10.1099/00221287-144-10-2697
P478
144 ( Pt 10)
P577
1998-10-01T00:00:00Z