Purification and characterization of Mycobacterium tuberculosis 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, MshB, a mycothiol biosynthetic enzyme
about
Biosynthesis and functions of mycothiol, the unique protective thiol of ActinobacteriaBacillithiol: a key protective thiol in Staphylococcus aureusBiosynthetic origin of the galactosamine substituent of Arabinogalactan in Mycobacterium tuberculosisBiochemistry of the initial steps of mycothiol biosynthesisEvaluation of NTF1836 as an inhibitor of the mycothiol biosynthetic enzyme MshC in growing and non-replicating Mycobacterium tuberculosis.Characterization of the N-acetyl-α-D-glucosaminyl l-malate synthase and deacetylase functions for bacillithiol biosynthesis in Bacillus anthracis .Drug targets in mycobacterial sulfur metabolism.New targets and inhibitors of mycobacterial sulfur metabolism.Examination of mechanism of N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-α-D-glucopyranoside deacetylase (MshB) reveals unexpected role for dynamic tyrosineThe lipoprotein LpqW is essential for the mannosylation of periplasmic glycolipids in Corynebacteria.Structures and mechanisms of the mycothiol biosynthetic enzymes.Chapter 2: Biogenesis of the cell wall and other glycoconjugates of Mycobacterium tuberculosis.Recent advances in antituberculous drug development and novel drug targets.Mycothiol: a target for potentiation of rifampin and other antibiotics against Mycobacterium tuberculosis.Structure and function of the LmbE-like superfamily.Physiological roles of mycothiol in detoxification and tolerance to multiple poisonous chemicals in Corynebacterium glutamicum.Development of new antituberculous agents based on new drug targets and structure-activity relationship.The activity and cofactor preferences of N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) change depending on environmental conditions.Automated docking studies provide insights into molecular determinants of ligand recognition by N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-α-D-glucopyranoside deacetylase (MshB).Identity of cofactor bound to mycothiol conjugate amidase (Mca) influenced by expression and purification conditions.An enzyme-initiated Smiles rearrangement enables the development of an assay of MshB, the GlcNAc-Ins deacetylase of mycothiol biosynthesis.
P2860
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P2860
Purification and characterization of Mycobacterium tuberculosis 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, MshB, a mycothiol biosynthetic enzyme
description
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im März 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/06/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/06/01)
@nl
наукова стаття, опублікована в червні 2006
@uk
مقالة علمية (نشرت في يونيو 2006)
@ar
name
Purification and characterizat ...... mycothiol biosynthetic enzyme
@ast
Purification and characterizat ...... mycothiol biosynthetic enzyme
@en
Purification and characterizat ...... mycothiol biosynthetic enzyme
@nl
type
label
Purification and characterizat ...... mycothiol biosynthetic enzyme
@ast
Purification and characterizat ...... mycothiol biosynthetic enzyme
@en
Purification and characterizat ...... mycothiol biosynthetic enzyme
@nl
prefLabel
Purification and characterizat ...... mycothiol biosynthetic enzyme
@ast
Purification and characterizat ...... mycothiol biosynthetic enzyme
@en
Purification and characterizat ...... mycothiol biosynthetic enzyme
@nl
P2093
P1476
Purification and characterizat ...... mycothiol biosynthetic enzyme
@en
P2093
Gerald L Newton
Philong Ta
Robert C Fahey
P304
P356
10.1016/J.PEP.2006.03.003
P577
2006-03-29T00:00:00Z