A unique Mycobacterium ESX-1 protein co-secretes with CFP-10/ESAT-6 and is necessary for inhibiting phagosome maturation
about
ESX-1 secreted virulence factors are recognized by multiple cytosolic AAA ATPases in pathogenic mycobacteriaModular Organization of the ESX-5 Secretion System in Mycobacterium tuberculosisEvolutionary landscape of the Mycobacterium tuberculosis complex from the viewpoint of PhoPR: implications for virulence regulation and application to vaccine developmentStructure of the Mycosin-1 Protease from the Mycobacterial ESX-1 Protein Type VII Secretion SystemUnderstanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysisThe putative propeptide of MycP1 in mycobacterial type VII secretion system does not inhibit protease activity but improves protein stabilityA β-Lactamase based reporter system for ESX dependent protein translocation in mycobacteriaMycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulenceEspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrityMycobacterial Esx-3 is required for mycobactin-mediated iron acquisitionCharacterization of Rv3868, an essential hypothetical protein of the ESX-1 secretion system in Mycobacterium tuberculosisApplication of the 4D fingerprint method with a robust scoring function for scaffold-hopping and drug repurposing strategies.PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence.Systematic genetic nomenclature for type VII secretion systems.Novel mycosin protease MycP₁ inhibitors identified by virtual screening and 4D fingerprintsContrasting transcriptional responses of a virulent and an attenuated strain of Mycobacterium tuberculosis infecting macrophagesTo catch a killer. What can mycobacterial models teach us about Mycobacterium tuberculosis pathogenesis?Distributive Conjugal Transfer: New Insights into Horizontal Gene Transfer and Genetic Exchange in MycobacteriaCorrelation of phenotypic profiles using targeted proteomics identifies mycobacterial esx-1 substrates.Revealing of Mycobacterium marinum transcriptome by RNA-seqThe ESX system in Bacillus subtilis mediates protein secretion.ESAT-6 Targeting to DEC205+ Antigen Presenting Cells Induces Specific-T Cell Responses against ESAT-6 and Reduces Pulmonary Infection with Virulent Mycobacterium tuberculosis.A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis.Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.A Duplicated ESAT-6 Region of ESX-5 Is Involved in Protein Export and Virulence of Mycobacteria.Insufficient Generation of Mycobactericidal Mediators and Inadequate Level of Phagosomal Maturation Are Related with Susceptibility to Virulent Mycobacterium tuberculosis Infection in Mouse Macrophages.EsaC substrate for the ESAT-6 secretion pathway and its role in persistent infections of Staphylococcus aureus.Molecular mechanisms of host-pathogen interactions and their potential for the discovery of new drug targetsA novel recombinant DNA vaccine encoding Mycobacterium tuberculosis ESAT-6 and FL protects against Mycobacterium tuberculosis challenge in mice.Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganismsProtein export systems of Mycobacterium tuberculosis: novel targets for drug development?The ins and outs of Mycobacterium tuberculosis protein export.Virulence factors of the Mycobacterium tuberculosis complexFunctional analysis of the EspR binding sites upstream of espR in Mycobacterium tuberculosis.Solution structure of the Mycobacterium tuberculosis EsxG·EsxH complex: functional implications and comparisons with other M. tuberculosis Esx family complexes.EspR-dependent ESAT-6 Protein Secretion of Mycobacterium tuberculosis Requires the Presence of Virulence Regulator PhoP.Secretome profile analysis of hypervirulent Mycobacterium tuberculosis CPT31 reveals increased production of EsxB and proteins involved in adaptation to intracellular lifestyle.The specialized secretory apparatus ESX-1 is essential for DNA transfer in Mycobacterium smegmatis.Evidence for pore formation in host cell membranes by ESX-1-secreted ESAT-6 and its role in Mycobacterium marinum escape from the vacuole.The Mycobacterium tuberculosis SecA2 system subverts phagosome maturation to promote growth in macrophages.
P2860
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P2860
A unique Mycobacterium ESX-1 protein co-secretes with CFP-10/ESAT-6 and is necessary for inhibiting phagosome maturation
description
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im November 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/11/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/11/01)
@nl
наукова стаття, опублікована в листопаді 2007
@uk
مقالة علمية (نشرت في نوفمبر 2007)
@ar
name
A unique Mycobacterium ESX-1 p ...... nhibiting phagosome maturation
@ast
A unique Mycobacterium ESX-1 p ...... nhibiting phagosome maturation
@en
A unique Mycobacterium ESX-1 p ...... nhibiting phagosome maturation
@nl
type
label
A unique Mycobacterium ESX-1 p ...... nhibiting phagosome maturation
@ast
A unique Mycobacterium ESX-1 p ...... nhibiting phagosome maturation
@en
A unique Mycobacterium ESX-1 p ...... nhibiting phagosome maturation
@nl
prefLabel
A unique Mycobacterium ESX-1 p ...... nhibiting phagosome maturation
@ast
A unique Mycobacterium ESX-1 p ...... nhibiting phagosome maturation
@en
A unique Mycobacterium ESX-1 p ...... nhibiting phagosome maturation
@nl
P2093
P2860
P3181
P1476
A unique Mycobacterium ESX-1 p ...... nhibiting phagosome maturation
@en
P2093
Catherine Fenselau
Jennifer Smith
Joanna Manoranjan
Lian-Yong Gao
Mark Masciocchi
Nathan Edwards
Olli Laine
Shao Jun Du
Xiaoping Zhu
P2860
P304
P3181
P356
10.1111/J.1365-2958.2007.05959.X
P407
P577
2007-11-01T00:00:00Z