A genome-wide RNAi screen in Caenorhabditis elegans identifies the nicotinic acetylcholine receptor subunit ACR-7 as an antipsychotic drug target
about
C. elegans in high-throughput drug discoveryDrug-dependent behaviors and nicotinic acetylcholine receptor expressions in Caenorhabditis elegans following chronic nicotine exposure.Drug elucidation: invertebrate genetics sheds new light on the molecular targets of CNS drugs.Exploring the genetic underpinnings of brain and behavioral disordersChallenges in understanding psychiatric disorders and developing therapeutics: a role for zebrafish.Forward Genetic Screen in Caenorhabditis elegans Suggests F57A10.2 and acp-4 As Suppressors of C9ORF72 Related Phenotypes.Worming our way to novel drug discovery with the Caenorhabditis elegans proteostasis network, stress response and insulin-signaling pathways.Methods for studying the mechanisms of action of antipsychotic drugs in Caenorhabditis elegans.Exploring Potential Germline-Associated Roles of the TRIM-NHL Protein NHL-2 Through RNAi ScreeningTransient receptor potential melastatin (TRPM) channels mediate clozapine-induced phenotypes in Caenorhabditis elegans.Clozapine Modulates Glucosylceramide, Clears Aggregated Proteins, and Enhances ATG8/LC3 in Caenorhabditis elegans.
P2860
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P2860
A genome-wide RNAi screen in Caenorhabditis elegans identifies the nicotinic acetylcholine receptor subunit ACR-7 as an antipsychotic drug target
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A genome-wide RNAi screen in C ...... s an antipsychotic drug target
@ast
A genome-wide RNAi screen in C ...... s an antipsychotic drug target
@en
A genome-wide RNAi screen in C ...... s an antipsychotic drug target
@nl
type
label
A genome-wide RNAi screen in C ...... s an antipsychotic drug target
@ast
A genome-wide RNAi screen in C ...... s an antipsychotic drug target
@en
A genome-wide RNAi screen in C ...... s an antipsychotic drug target
@nl
prefLabel
A genome-wide RNAi screen in C ...... s an antipsychotic drug target
@ast
A genome-wide RNAi screen in C ...... s an antipsychotic drug target
@en
A genome-wide RNAi screen in C ...... s an antipsychotic drug target
@nl
P2093
P2860
P3181
P1433
P1476
A genome-wide RNAi screen in C ...... s an antipsychotic drug target
@en
P2093
Angelica Ortiz
Bruce M Cohen
Edgar A Buttner
Gregory R Sliwoski
Sarah E DeMarco
Taixiang Saur
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1003313
P407
P577
2013-01-01T00:00:00Z