Amplified expression of the tag+ and alkA+ genes in Escherichia coli: identification of gene products and effects on alkylation resistance
about
Cloning and expression in Escherichia coli of a gene for an alkylbase DNA glycosylase from Saccharomyces cerevisiae; a homologue to the bacterial alkA gene.A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD.Release of normal bases from intact DNA by a native DNA repair enzyme.Imbalanced base excision repair increases spontaneous mutation and alkylation sensitivity in Escherichia coli.Base excision repair in a network of defence and tolerance.Generation of a strong mutator phenotype in yeast by imbalanced base excision repair.The Ada protein acts as both a positive and a negative modulator of Escherichia coli's response to methylating agents.Bacillus subtilis alkA gene encoding inducible 3-methyladenine DNA glycosylase is adjacent to the ada operonAlteration of the carboxyl-terminal domain of Ada protein influences its inducibility, specificity, and strength as a transcriptional activatorBalancing repair and tolerance of DNA damage caused by alkylating agentsFunctions of the gene products of Escherichia coli.Chromosomal islands of Streptococcus pyogenes and related streptococci: molecular switches for survival and virulence.Evidence for unique DNA repair activity encoded by a cloned Serratia marcescens gene: suppression of Escherichia coli mutations that reduce repair of alkylated DNA.Excision of 3-methylguanine from alkylated DNA by 3-methyladenine DNA glycosylase I of Escherichia coli.Purification and characterization of 3-methyladenine DNA glycosylase I from Escherichia coli.Expression of the E.coli 3-methyladenine DNA glycosylase I gene in mammalian cells reduces the toxic and mutagenic effects of methylating agents.Involvement of Escherichia coli DNA polymerase IV in tolerance of cytotoxic alkylating DNA lesions in vivo.Different efficiencies of the Tag and AlkA DNA glycosylases from Escherichia coli in the removal of 3-methyladenine from single-stranded DNA.
P2860
Q27935462-53A0F596-88A2-434F-9114-54E6205B7A03Q30807594-4B08AD71-5089-473E-AEDD-76442738FB86Q33888049-0D0CEC4E-4977-439F-A608-3A141C1B01D0Q33993117-8E49B666-7A4E-46E5-918B-365C4ED993BDQ34283911-072B0D94-D5BF-4CA6-96BF-B9DF4DAC4D80Q34750817-15F041ED-6809-471D-B97F-12058548EB5BQ35809531-EEBD61A8-62C5-4DAF-91CB-777753D9C194Q36122339-1EBB51C4-4C66-4B22-8F19-27F30FD318B1Q36222477-77A489A1-4059-4D7C-8706-498FA3B7E29AQ36651488-59DE5BD2-31E3-47C1-BF19-7BCFC1818AA6Q37059813-F4288C33-08F0-464A-B4DA-598AB1F7B6D8Q38243813-E323C342-A8FE-49B5-BD66-AE940315B212Q39950334-BE71938F-5D1C-4E17-A13F-2B307FB705D9Q40406779-C888F92B-E172-4CC2-9B0A-28C5C5F3C645Q40566046-0FDAEB3C-1136-49C3-AA6C-4B564584C50EQ41545350-E4E985D2-7745-48BA-9F9D-9BB51D226BA4Q42126464-4B45B973-3403-4CA5-9A46-B5ABCACE2A3CQ54577242-875BD4E6-D799-4F31-90A4-701953244C6F
P2860
Amplified expression of the tag+ and alkA+ genes in Escherichia coli: identification of gene products and effects on alkylation resistance
description
1986 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1986
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im November 1986 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 1986/11/01)
@sk
vědecký článek publikovaný v roce 1986
@cs
wetenschappelijk artikel (gepubliceerd op 1986/11/01)
@nl
наукова стаття, опублікована в листопаді 1986
@uk
مقالة علمية (نشرت في نوفمبر 1986)
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name
Amplified expression of the ta ...... fects on alkylation resistance
@ast
Amplified expression of the ta ...... fects on alkylation resistance
@en
Amplified expression of the ta ...... fects on alkylation resistance
@nl
type
label
Amplified expression of the ta ...... fects on alkylation resistance
@ast
Amplified expression of the ta ...... fects on alkylation resistance
@en
Amplified expression of the ta ...... fects on alkylation resistance
@nl
prefLabel
Amplified expression of the ta ...... fects on alkylation resistance
@ast
Amplified expression of the ta ...... fects on alkylation resistance
@en
Amplified expression of the ta ...... fects on alkylation resistance
@nl
P2093
P2860
P1476
Amplified expression of the ta ...... fects on alkylation resistance
@en
P2093
P2860
P304
P356
10.1128/JB.168.2.642-647.1986
P407
P577
1986-11-01T00:00:00Z