G2 arrest and impaired nucleocytoplasmic transport in mouse embryos lacking the proto-oncogene CAN/Nup214
about
RAE1 is a shuttling mRNA export factor that binds to a GLEBS-like NUP98 motif at the nuclear pore complex through multiple domainsELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell divisionThe human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 RevOverexpression of the nucleoporin CAN/NUP214 induces growth arrest, nucleocytoplasmic transport defects, and apoptosisThe Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to humanThe nucleoporin Nup153 is required for nuclear pore basket formation, nuclear pore complex anchoring and import of a subset of nuclear proteinsThe ornithine decarboxylase gene is essential for cell survival during early murine developmentCharacterization and targeted disruption of murine Nup50, a p27(Kip1)-interacting component of the nuclear pore complexDepletion of a single nucleoporin, Nup107, prevents the assembly of a subset of nucleoporins into the nuclear pore complexDisruption of the FG nucleoporin NUP98 causes selective changes in nuclear pore complex stoichiometry and functionA novel, nuclear pore-associated, widely distributed molecule overexpressed in oncogenesis and developmentNup84, a novel nucleoporin that is associated with CAN/Nup214 on the cytoplasmic face of the nuclear pore complexBub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesisTwo yeast nuclear pore complex proteins involved in mRNA export form a cytoplasmically oriented subcomplex.Building up the nucleus: nuclear organization in the establishment of totipotency and pluripotency during mammalian developmentNuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryoMultipotent cell lineages in early mouse development depend on SOX2 functionMice lacking the nuclear pore complex protein ALADIN show female infertility but fail to develop a phenotype resembling human triple A syndrome.Inhibition of nucleoporin member Nup214 expression by miR-133b perturbs mitotic timing and leads to cell death.Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration.Epstein-Barr virus EB2 protein exports unspliced RNA via a Crm-1-independent pathway.Identification and analysis of LNO1-like and AtGLE1-like nucleoporins in plantsNuclear distributions of NUP62 and NUP214 suggest architectural diversity and spatial patterning among nuclear pore complexes.Regulation of mRNA trafficking by nuclear pore complexes.Pax3-FKHR knock-in mice show developmental aberrations but do not develop tumors.Developmental genetics of the essential Drosophila nucleoporin nup154: allelic differences due to an outward-directed promoter in the P-element 3' end.Spartan deficiency causes genomic instability and progeroid phenotypes.Structural basis for assembly and function of the Nup82 complex in the nuclear pore scaffold.Biology and biophysics of the nuclear pore complex and its componentsmembers only encodes a Drosophila nucleoporin required for rel protein import and immune response activation.The role of Iex-1 in the pathogenesis of venous neointimal hyperplasia associated with hemodialysis arteriovenous fistulaNucleocytoplasmic transport: integrating mRNA production and turnover with export through the nuclear poreThe nuclear pore complex protein Elys is required for genome stability in mouse intestinal epithelial progenitor cells.SET-CAN, the product of the t(9;9) in acute undifferentiated leukemia, causes expansion of early hematopoietic progenitors and hyperproliferation of stomach mucosa in transgenic mice.Nup154, a new Drosophila gene essential for male and female gametogenesis is related to the nup155 vertebrate nucleoporin gene.Definition of global and transcript-specific mRNA export pathways in metazoans.Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation.The cytoplasmic filaments of the nuclear pore complex are dispensable for selective nuclear protein import.Nup358/RanBP2 attaches to the nuclear pore complex via association with Nup88 and Nup214/CAN and plays a supporting role in CRM1-mediated nuclear protein export.
P2860
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P2860
G2 arrest and impaired nucleocytoplasmic transport in mouse embryos lacking the proto-oncogene CAN/Nup214
description
1996 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1996
@ast
im Oktober 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1996/10/15)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/10/15)
@nl
наукова стаття, опублікована в жовтні 1996
@uk
научни чланак (објављен 1996/10/15)
@sr
name
G2 arrest and impaired nucleoc ...... the proto-oncogene CAN/Nup214
@ast
G2 arrest and impaired nucleoc ...... the proto-oncogene CAN/Nup214
@en
G2 arrest and impaired nucleoc ...... the proto-oncogene CAN/Nup214
@nl
type
label
G2 arrest and impaired nucleoc ...... the proto-oncogene CAN/Nup214
@ast
G2 arrest and impaired nucleoc ...... the proto-oncogene CAN/Nup214
@en
G2 arrest and impaired nucleoc ...... the proto-oncogene CAN/Nup214
@nl
prefLabel
G2 arrest and impaired nucleoc ...... the proto-oncogene CAN/Nup214
@ast
G2 arrest and impaired nucleoc ...... the proto-oncogene CAN/Nup214
@en
G2 arrest and impaired nucleoc ...... the proto-oncogene CAN/Nup214
@nl
P2093
P2860
P1433
P1476
G2 arrest and impaired nucleoc ...... the proto-oncogene CAN/Nup214
@en
P2093
P2860
P304
P407
P577
1996-10-01T00:00:00Z