Uroguanylin knockout mice have increased blood pressure and impaired natriuretic response to enteral NaCl load
about
Molecular and neuronal homology between the olfactory systems of zebrafish and mouseGastrorenal Axis.The importance of the gastrorenal axis in the control of body sodium homeostasisGastrin induces sodium-hydrogen exchanger 3 phosphorylation and mTOR activation via a phosphoinositide 3-kinase-/protein kinase C-dependent but AKT-independent pathway in renal proximal tubule cells derived from a normotensive male human.The Effect of Salt Intake and Potassium Supplementation on Serum Gastrin Levels in Chinese Adults: A Randomized Trial.Loss of guanylyl cyclase C (GCC) signaling leads to dysfunctional intestinal barrierThe uroguanylin system and human disease.Effect of guanylate cyclase-C activity on energy and glucose homeostasisNatriuretic and antikaliuretic effects of uroguanylin and prouroguanylin in the ratA uroguanylin-GUCY2C endocrine axis regulates feeding in mice.A comparison of linaclotide and lubiprostone dosing regimens on ion transport responses in human colonic mucosaThe rat kidney contains high levels of prouroguanylin (the uroguanylin precursor) but does not express GC-C (the enteric uroguanylin receptor).President's address: salt-too much of a good thing?Evidence for a signaling axis by which intestinal phosphate rapidly modulates renal phosphate reabsorption.Comparative transcriptional profiling of renal cortex in rats with inherited stress-induced arterial hypertension and normotensive Wistar Albino Glaxo rats.The pendrin anion exchanger gene is transcriptionally regulated by uroguanylin: a novel enterorenal linkLinks between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases.Hypertension, kidney, and transgenics: a fresh perspective.DOCA-salt hypertension does not require the ouabain-sensitive binding site of the α2 Na,K-ATPaseMembrane guanylyl cyclase receptors: an updateACTH-induced hypertension is dependent on the ouabain-binding site of the alpha2-Na+-K+-ATPase subunit.Guanylyl cyclase structure, function and regulation.Regulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases.Circulating prouroguanylin is processed to its active natriuretic form exclusively within the renal tubules.Uroguanylin, an intestinal natriuretic peptide, is delivered to the kidney as an unprocessed propeptide.Dietary salt regulates uroguanylin expression and signaling activity in the kidney, but not in the intestineActivation of guanylate cyclase C signaling pathway protects intestinal epithelial cells from acute radiation-induced apoptosis.Guanylin and uroguanylin are produced by mouse intestinal epithelial cells of columnar and secretory lineage.The natriuretic peptide uroguanylin elicits physiologic actions through 2 distinct topoisomersGastrin and D1 dopamine receptor interact to induce natriuresis and diuresis.Existing and emerging therapies for irritable bowel syndrome.Guanylin peptide family: history, interactions with ANP, and new pharmacological perspectives.Toxin mediated diarrhea in the 21 century: the pathophysiology of intestinal ion transport in the course of ETEC, V. cholerae and rotavirus infection.Pendrin, a novel transcriptional target of the uroguanylin system.Current understanding of guanylin peptides actions.Molecular Physiology of Membrane Guanylyl Cyclase Receptors.Mechanisms underlying the inhibitory effects of uroguanylin on NHE3 transport activity in renal proximal tubule.A novel role for uroguanylin in the regulation of sodium balance.Developmental expression and biological activity of gastrin-releasing peptide and its receptors in the kidney.Defying the stereotype: non-canonical roles of the Peptide hormones guanylin and uroguanylin.
P2860
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P2860
Uroguanylin knockout mice have increased blood pressure and impaired natriuretic response to enteral NaCl load
description
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im Oktober 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/10/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/10/01)
@nl
наукова стаття, опублікована в жовтні 2003
@uk
مقالة علمية (نشرت في أكتوبر 2003)
@ar
name
Uroguanylin knockout mice have ...... response to enteral NaCl load
@ast
Uroguanylin knockout mice have ...... response to enteral NaCl load
@en
Uroguanylin knockout mice have ...... response to enteral NaCl load
@nl
type
label
Uroguanylin knockout mice have ...... response to enteral NaCl load
@ast
Uroguanylin knockout mice have ...... response to enteral NaCl load
@en
Uroguanylin knockout mice have ...... response to enteral NaCl load
@nl
prefLabel
Uroguanylin knockout mice have ...... response to enteral NaCl load
@ast
Uroguanylin knockout mice have ...... response to enteral NaCl load
@en
Uroguanylin knockout mice have ...... response to enteral NaCl load
@nl
P2093
P2860
P3181
P1476
Uroguanylin knockout mice have ...... response to enteral NaCl load
@en
P2093
Jenine Sabo
Jennifer A Hawkins
John N Lorenz
L Philip Sanford
Lane L Clarke
Lara R Gawenis
Michelle Nieman
Noeet Elitsur
P2860
P304
P3181
P356
10.1172/JCI18743
10.1172/JCI200318743
P407
P577
2003-10-01T00:00:00Z