Adenovirus-mediated knockout of a conditional glucokinase gene in isolated pancreatic islets reveals an essential role for proximal metabolic coupling events in glucose-stimulated insulin secretion
about
Critical role of gap junction coupled KATP channel activity for regulated insulin secretionTwo-photon fluorescence spectroscopy and microscopy of NAD(P)H and flavoprotein.Naturally occurring glucokinase mutations are associated with defects in posttranslational S-nitrosylation.Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells.Cellular origin of hexokinase in pancreatic islets.Gene-altered mice and metabolic flux control.Functional studies in living animals using multiphoton microscopy.Microfluidic glucose stimulation reveals limited coordination of intracellular Ca2+ activity oscillations in pancreatic isletsCellular communication and heterogeneity in pancreatic islet insulin secretion dynamics.Efficient gene activation in cultured mammalian cells mediated by FLP recombinase-expressing recombinant adenovirusAll mixed up: defining roles for β-cell subtypes in mature islets.Practical range of effective dose for Cre recombinase-expressing recombinant adenovirus without cell toxicity in mammalian cells.Relative hypoglycemia and hyperinsulinemia in mice with heterozygous lipoprotein lipase (LPL) deficiency. Islet LPL regulates insulin secretion.beta-cell adaptation in 60% pancreatectomy rats that preserves normoinsulinemia and normoglycemia.A functional link between glucokinase binding to insulin granules and conformational alterations in response to glucose and insulin.Spatially Organized β-Cell Subpopulations Control Electrical Dynamics across Islets of Langerhans.New Understanding of β-Cell Heterogeneity and In Situ Islet Function.The role of beta cell heterogeneity in islet function and insulin release.
P2860
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P2860
Adenovirus-mediated knockout of a conditional glucokinase gene in isolated pancreatic islets reveals an essential role for proximal metabolic coupling events in glucose-stimulated insulin secretion
description
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1999
@ast
im Januar 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/01/08)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/01/08)
@nl
наукова стаття, опублікована в січні 1999
@uk
name
Adenovirus-mediated knockout o ...... e-stimulated insulin secretion
@ast
Adenovirus-mediated knockout o ...... e-stimulated insulin secretion
@en
Adenovirus-mediated knockout o ...... e-stimulated insulin secretion
@nl
type
label
Adenovirus-mediated knockout o ...... e-stimulated insulin secretion
@ast
Adenovirus-mediated knockout o ...... e-stimulated insulin secretion
@en
Adenovirus-mediated knockout o ...... e-stimulated insulin secretion
@nl
prefLabel
Adenovirus-mediated knockout o ...... e-stimulated insulin secretion
@ast
Adenovirus-mediated knockout o ...... e-stimulated insulin secretion
@en
Adenovirus-mediated knockout o ...... e-stimulated insulin secretion
@nl
P2093
P2860
P921
P356
P1476
Adenovirus-mediated knockout o ...... e-stimulated insulin secretion
@en
P2093
D. W. Piston
K. D. Shelton
M. A. Magnuson
S. M. Knobel
P2860
P304
P356
10.1074/JBC.274.2.1000
P407
P577
1999-01-08T00:00:00Z