Otx2 regulates subtype specification and neurogenesis in the midbrain
about
Gene function in early mouse embryonic stem cell differentiation.LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stressA novel dominant negative mutation of OTX2 associated with combined pituitary hormone deficiencymiRNAs As Emerging Regulators of Oligodendrocyte Development and DifferentiationSubset specification of central serotonergic neuronsAberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cellsWnt/β-catenin signaling in midbrain dopaminergic neuron specification and neurogenesis.Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathwayOtx2 Requires Lmx1b to Control the Development of Mesodiencephalic Dopaminergic NeuronsOTX2 Transcription Factor Controls Regional Patterning within the Medial Ganglionic Eminence and Regional Identity of the SeptumThe mammalian DM domain transcription factor Dmrta2 is required for early embryonic development of the cerebral cortexReproductive dysfunction and decreased GnRH neurogenesis in a mouse model of CHARGE syndrome.Temporal and spatial delineation of mouse Otx2 functions by conditional self-knockoutMicroRNA-mediated control of oligodendrocyte differentiation.The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons.Transcription factor binding dynamics during human ES cell differentiationDeletion of Otx2 in GnRH neurons results in a mouse model of hypogonadotropic hypogonadism.The production of somatostatin interneurons in the olfactory bulb is regulated by the transcription factor sp8.Global expression profiling reveals genetic programs underlying the developmental divergence between mouse and human embryogenesis.Molecular marker differences relate to developmental position and subsets of mesodiencephalic dopaminergic neurons.An Lmx1b-miR135a2 regulatory circuit modulates Wnt1/Wnt signaling and determines the size of the midbrain dopaminergic progenitor pool.Dynamic network-based relevance score reveals essential proteins and functional modules in directed differentiation.Thyroid Hormone-Otx2 Signaling Is Required for Embryonic Ventral Midbrain Neural Stem Cells Differentiated into Dopamine NeuronsDopaminergic neurons modulate GABA neuron migration in the embryonic midbrain.Strategies to unravel molecular codes essential for the development of meso-diencephalic dopaminergic neurons.Genetic networks controlling the development of midbrain dopaminergic neurons.Dynamic temporal requirement of Wnt1 in midbrain dopamine neuron development.Regulation of differentiation flux by Notch signalling influences the number of dopaminergic neurons in the adult brain.Novel mutations in PAX6, OTX2 and NDP in anophthalmia, microphthalmia and coloboma.Conditional deletion of neurogenin-3 using Nkx2.1iCre results in a mouse model for the central control of feeding, activity and obesityDopaminergic neurons derived from BG01V2, a variant of human embryonic stem cell line BG01.Midbrain dopaminergic neuron fate specification: Of mice and embryonic stem cells.Changes in Otx2 and parvalbumin immunoreactivity in the superior colliculus in the platelet-derived growth factor receptor-β knockout miceOTX2 impedes self-renewal of porcine iPS cells through downregulation of NANOG expressionFunctional roles of Nurr1, Pitx3, and Lmx1a in neurogenesis and phenotype specification of dopamine neurons during in vitro differentiation of embryonic stem cells.Development and function of the midbrain dopamine system: what we know and what we need toSurvival of a Novel Subset of Midbrain Dopaminergic Neurons Projecting to the Lateral Septum Is Dependent on NeuroD Proteins.Cellular programming and reprogramming: sculpting cell fate for the production of dopamine neurons for cell therapy.Genetic control of midbrain dopaminergic neuron development.OTX2 Activity at Distal Regulatory Elements Shapes the Chromatin Landscape of Group 3 Medulloblastoma.
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P2860
Otx2 regulates subtype specification and neurogenesis in the midbrain
description
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Mai 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/05/11)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/05/11)
@nl
наукова стаття, опублікована в травні 2005
@uk
مقالة علمية نشرت في 11-5-2005 حول موضوع: دماغ
@ar
name
Otx2 regulates subtype specification and neurogenesis in the midbrain
@ast
Otx2 regulates subtype specification and neurogenesis in the midbrain
@en
Otx2 regulates subtype specification and neurogenesis in the midbrain
@nl
type
label
Otx2 regulates subtype specification and neurogenesis in the midbrain
@ast
Otx2 regulates subtype specification and neurogenesis in the midbrain
@en
Otx2 regulates subtype specification and neurogenesis in the midbrain
@nl
prefLabel
Otx2 regulates subtype specification and neurogenesis in the midbrain
@ast
Otx2 regulates subtype specification and neurogenesis in the midbrain
@en
Otx2 regulates subtype specification and neurogenesis in the midbrain
@nl
P2093
P50
P921
P3181
P1476
Otx2 regulates subtype specification and neurogenesis in the midbrain
@en
P2093
Muriel Koch
Ryoichiro Kageyama
Siew-Lan Ang
P304
P3181
P356
10.1523/JNEUROSCI.5158-04.2005
P407
P577
2005-05-01T00:00:00Z