The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage
about
Mammary Development and Breast Cancer: A Wnt PerspectiveDevelopmental signaling pathways regulating mammary stem cells and contributing to the etiology of triple-negative breast cancerForm and function: how estrogen and progesterone regulate the mammary epithelial hierarchyThe mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapesA phenotypic mouse model of basaloid breast tumorsBoth canonical and non-canonical Wnt signaling independently promote stem cell growth in mammospheresWnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in cultureThe WNT-controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineageWnt5a Signaling in Normal and Cancer Stem CellsHuman milk protein production in xenografts of genetically engineered bovine mammary epithelial stem cells.The Terminal End Bud: the Little Engine that Could.Molecular mechanisms guiding embryonic mammary gland development.Differentiation generates paracrine cell pairs that maintain basaloid mouse mammary tumors: proof of concept.Stem cells and the developing mammary gland.SOST and DKK: Antagonists of LRP Family Signaling as Targets for Treating Bone Disease.Activation status of Wnt/ß-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouseWnt and mammary stem cells: hormones cannot fly wingless.R-spondin1 is a novel hormone mediator for mammary stem cell self-renewalThe epigenetic landscape of mammary gland development and functional differentiation.Genotoxic exposure during juvenile growth of mammary gland depletes stem cell activity and inhibits Wnt signaling.Wnt5a suppresses tumor formation and redirects tumor phenotype in MMTV-Wnt1 tumors.Intra-platform comparison of 25-mer and 60-mer oligonucleotide Nimblegen DNA microarraysMurine mammary epithelial stem cells: discovery, function, and current status.Key signaling nodes in mammary gland development and cancer: β-catenin.Wnt/catenin signaling in adult stem cell physiology and disease.Wnt5a as an effector of TGFβ in mammary development and cancerKrt6a-positive mammary epithelial progenitors are not at increased vulnerability to tumorigenesis initiated by ErbB2.Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium.Mammary cells with active Wnt signaling resist ErbB2-induced tumorigenesisSLIT/ROBO1 signaling suppresses mammary branching morphogenesis by limiting basal cell numberKeratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer.From milk to malignancy: the role of mammary stem cells in development, pregnancy and breast cancer.Two Isoforms of the RNA Binding Protein, Coding Region Determinant-binding Protein (CRD-BP/IGF2BP1), Are Expressed in Breast Epithelium and Support Clonogenic Growth of Breast Tumor CellsBoth LRP5 and LRP6 receptors are required to respond to physiological Wnt ligands in mammary epithelial cells and fibroblasts.The mammary stem cell conundrum: is it unipotent or multipotent?Wnt signaling in mammary glands: plastic cell fates and combinatorial signaling.Lgr5-expressing cells are sufficient and necessary for postnatal mammary gland organogenesis.SOX9 regulates low density lipoprotein receptor-related protein 6 (LRP6) and T-cell factor 4 (TCF4) expression and Wnt/β-catenin activation in breast cancer.Lrp5 Has a Wnt-Independent Role in Glucose Uptake and Growth for Mammary Epithelial CellsCell Fate Decisions During Breast Cancer Development.
P2860
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P2860
The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage
description
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique PLoS ONE
@fr
artículu científicu espublizáu en 2009
@ast
im August 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/08/12)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/08/12)
@nl
наукова стаття, опублікована в серпні 2009
@uk
name
The Wnt receptor, Lrp5, is exp ...... to maintain the basal lineage
@ast
The Wnt receptor, Lrp5, is exp ...... to maintain the basal lineage
@en
The Wnt receptor, Lrp5, is exp ...... to maintain the basal lineage
@nl
type
label
The Wnt receptor, Lrp5, is exp ...... to maintain the basal lineage
@ast
The Wnt receptor, Lrp5, is exp ...... to maintain the basal lineage
@en
The Wnt receptor, Lrp5, is exp ...... to maintain the basal lineage
@nl
prefLabel
The Wnt receptor, Lrp5, is exp ...... to maintain the basal lineage
@ast
The Wnt receptor, Lrp5, is exp ...... to maintain the basal lineage
@en
The Wnt receptor, Lrp5, is exp ...... to maintain the basal lineage
@nl
P2093
P2860
P3181
P1433
P1476
The Wnt receptor, Lrp5, is exp ...... to maintain the basal lineage
@en
P2093
Anna Bafico
Bart O. Williams
Caroline M. Alexander
Charlotta Lindvall
Kristine S. Klos
Nisha M. Badders
Rod J. Clark
Shruti Goel
Soyoung Kim
P2860
P3181
P356
10.1371/JOURNAL.PONE.0006594
P407
P577
2009-08-12T00:00:00Z