Planar cell polarity effector gene Fuzzy regulates cilia formation and Hedgehog signal transduction in mouse
about
Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humansTrafficking to the ciliary membrane: how to get across the periciliary diffusion barrier?The ciliary membrane.Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromesA hypomorphic allele reveals an important role of inturned in mouse skeletal developmentPlanar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary ciliaPCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tubeFuz regulates craniofacial development through tissue specific responses to signaling factorsThe primary cilium: a signalling centre during vertebrate developmentFrom Planar Cell Polarity to Ciliogenesis and Back: The Curious Tale of the PPE and CPLANE proteins.Cilia-mediated Hedgehog signaling controls form and function in the mammalian larynx.The proteins encoded by the Drosophila Planar Polarity Effector genes inturned, fuzzy and fritz interact physically and can re-pattern the accumulation of "upstream" Planar Cell Polarity proteins.Control of vertebrate intraflagellar transport by the planar cell polarity effector FuzFunctional characterization of Prickle2 and BBS7 identify overlapping phenotypes yet distinct mechanisms.Testin interacts with vangl2 genetically to regulate inner ear sensory cell orientation and the normal development of the female reproductive tract in mice.A role for planar cell polarity during early endoderm morphogenesis.Genome-wide RNAi screen identifies novel host proteins required for alphavirus entry.The roles of maternal Vangl2 and aPKC in Xenopus oocyte and embryo patterningIn vivo investigation of cilia structure and function using XenopusPlanar cell polarity in Drosophila.Cilia, Wnt signaling, and the cytoskeletonThe relationship between sonic Hedgehog signaling, cilia, and neural tube defectsmiR-219 regulates neural progenitors by dampening apical Par protein-dependent Hedgehog signalingCilia gene mutations cause atrioventricular septal defects by multiple mechanisms.Planar cell polarity signaling, cilia and polarized ciliary beatingStrange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia.Principles of planar polarity in animal developmentPlanar cell polarity: coordinating morphogenetic cell behaviors with embryonic polarityA consideration of the evidence that genetic defects in planar cell polarity contribute to the etiology of human neural tube defects.Primary cilia and graded Sonic Hedgehog signaling.Genetic evidence in planar cell polarity signaling pathway in human neural tube defects.Meckel-Gruber syndrome and the role of primary cilia in kidney, skeleton, and central nervous system developmentCilia and polycystic kidney disease, kith and kin.Expanding the mutational spectrum associated to neural tube defects: literature revision and description of novel VANGL1 mutations.Effect of localization, length and orientation of chondrocytic primary cilium on murine growth plate organization.INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma.Primary Cilia and Mammalian Hedgehog Signaling.An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome.Common skeletal features in rare diseases: New links between ciliopathies and FGF-related syndromes.Patterning skin by planar cell polarity: the multi-talented hair designer
P2860
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P2860
Planar cell polarity effector gene Fuzzy regulates cilia formation and Hedgehog signal transduction in mouse
description
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im Dezember 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/12/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/12/01)
@nl
наукова стаття, опублікована в грудні 2009
@uk
مقالة علمية (نشرت في ديسمبر 2009)
@ar
name
Planar cell polarity effector ...... g signal transduction in mouse
@ast
Planar cell polarity effector ...... g signal transduction in mouse
@en
Planar cell polarity effector ...... g signal transduction in mouse
@nl
type
label
Planar cell polarity effector ...... g signal transduction in mouse
@ast
Planar cell polarity effector ...... g signal transduction in mouse
@en
Planar cell polarity effector ...... g signal transduction in mouse
@nl
prefLabel
Planar cell polarity effector ...... g signal transduction in mouse
@ast
Planar cell polarity effector ...... g signal transduction in mouse
@en
Planar cell polarity effector ...... g signal transduction in mouse
@nl
P2093
P356
P1476
Planar cell polarity effector ...... g signal transduction in mouse
@en
P2093
Huiqing Zeng
Westley Heydeck
P304
P356
10.1002/DVDY.22130
P577
2009-12-01T00:00:00Z