Fyn kinase-mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain
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Regulation of NMDA receptors by the tyrosine kinase FynMetabolite profiles correlate closely with neurobehavioral function in experimental spinal cord injury in ratsCurcumin suppresses soluble tau dimers and corrects molecular chaperone, synaptic, and behavioral deficits in aged human tau transgenic miceGlutamate receptor ion channels: structure, regulation, and functionPersistent changes in spinal cord gene expression after recovery from inflammatory hyperalgesia: a preliminary study on pain memory.BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminalsThe use of ketamine in complex regional pain syndrome: possible mechanisms.Blockade of lysosomal acid ceramidase induces GluN2B-dependent Tau phosphorylation in rat hippocampal slices.Involvement of spinal NR2B-containing NMDA receptors in oxaliplatin-induced mechanical allodynia in rats.Involvement of EphB1 receptors signalling in models of inflammatory and neuropathic pain.Targeting N-methyl-D-aspartate receptors for treatment of neuropathic painEthanol-induced increase in Fyn kinase activity in the dorsomedial striatum is associated with subcellular redistribution of protein tyrosine phosphatase αRapid S-nitrosylation of actin by NO-generating donors and in inflammatory pain model mice.Inhibition of Ca2+/calmodulin-dependent protein kinase II reverses oxaliplatin-induced mechanical allodynia in rats.Regulation of Nociceptive Plasticity Threshold and DARPP-32 Phosphorylation in Spinal Dorsal Horn Neurons by Convergent Dopamine and Glutamate InputsMagnesium sulphate attenuate remifentanil-induced postoperative hyperalgesia via regulating tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cordInvolvement of Tyr1472 phosphorylation of NMDA receptor NR2B subunit in postherpetic neuralgia in model mice.Striatal-enriched protein tyrosine phosphatase modulates nociception: evidence from genetic deletion and pharmacological inhibitionActivation of spinal MrgC-Gi-NR2B-nNOS signaling pathway by Mas oncogene-related gene C receptor agonist bovine adrenal medulla 8-22 attenuates bone cancer pain in mice.Functional identification of NR2 subunits contributing to NMDA receptors on substance P receptor-expressing dorsal horn neurons.CCL-1 in the spinal cord contributes to neuropathic pain induced by nerve injury.Post-synaptic density-93 mediates tyrosine-phosphorylation of the N-methyl-D-aspartate receptors.Surgical incision-induced nociception causes cognitive impairment and reduction in synaptic NMDA receptor 2B in miceInvolvement of Brain-Enriched Guanylate Kinase-Associated Protein (BEGAIN) in Chronic Pain after Peripheral Nerve Injury.NR2B Expression in Rat DRG Is Differentially Regulated Following Peripheral Nerve Injuries That Lead to Transient or Sustained Stimuli-Evoked Hypersensitivity.Central sensitization: a generator of pain hypersensitivity by central neural plasticity.Glutamate receptor phosphorylation and trafficking in pain plasticity in spinal cord dorsal horn.Dysregulated Src upregulation of NMDA receptor activity: a common link in chronic pain and schizophrenia.Ephrins and pain.Calcium-permeable ion channels in pain signaling.Endogenous analgesia, dependence, and latent pain sensitizationThe role of N-methyl-D-aspartate receptor subunit NR2B in spinal cord in cancer pain.Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complexNMDA receptors in primary afferents require phosphorylation by Src family kinases to induce substance P release in the rat spinal cord.Phosphorylation of NMDA receptor GluN2B subunit at Tyr1472 is important for trigeminal processing of itch.Neural cell adhesion molecule and its polysialic acid moiety exhibit opposing and linked effects on neuropathic hyperalgesia.NMDA receptor mediates chronic visceral pain induced by neonatal noxious somatic stimulation.Dopamine-induced tyrosine phosphorylation of NR2B (Tyr1472) is essential for ERK1/2 activation and processing of novel taste information.Role of Fyn-mediated NMDA receptor function in prediabetic neuropathy in mice.Governing role of primary afferent drive in increased excitation of spinal nociceptive neurons in a model of sciatic neuropathy.
P2860
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P2860
Fyn kinase-mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain
description
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im September 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/09/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/09/01)
@nl
наукова стаття, опублікована у вересні 2005
@uk
مقالة علمية (نشرت في سبتمبر 2005)
@ar
name
Fyn kinase-mediated phosphoryl ...... aintenance of neuropathic pain
@ast
Fyn kinase-mediated phosphoryl ...... aintenance of neuropathic pain
@en
Fyn kinase-mediated phosphoryl ...... aintenance of neuropathic pain
@nl
type
label
Fyn kinase-mediated phosphoryl ...... aintenance of neuropathic pain
@ast
Fyn kinase-mediated phosphoryl ...... aintenance of neuropathic pain
@en
Fyn kinase-mediated phosphoryl ...... aintenance of neuropathic pain
@nl
prefLabel
Fyn kinase-mediated phosphoryl ...... aintenance of neuropathic pain
@ast
Fyn kinase-mediated phosphoryl ...... aintenance of neuropathic pain
@en
Fyn kinase-mediated phosphoryl ...... aintenance of neuropathic pain
@nl
P2093
P921
P3181
P1476
Fyn kinase-mediated phosphoryl ...... aintenance of neuropathic pain
@en
P2093
Akitsugu Yamamoto
Kotaro Hattori
Kunio Takagi
Masahiko Watanabe
Masayoshi Mishina
Shinji Matsumura
Tadashi Yamamoto
Takanobu Nakazawa
Takeshi Yagi
P304
P3181
P356
10.1111/J.1460-9568.2005.04340.X
P407
P577
2005-09-01T00:00:00Z