Electroretinographic anomalies in mice with mutations in Myo7a, the gene involved in human Usher syndrome type 1B
about
Mutations of the protocadherin gene PCDH15 cause Usher syndrome type 1FUsher syndrome: animal models, retinal function of Usher proteins, and prospects for gene therapyThe many different cellular functions of MYO7A in the retinaCLRN1 is nonessential in the mouse retina but is required for cochlear hair cell developmentAbnormal phagocytosis by retinal pigmented epithelium that lacks myosin VIIa, the Usher syndrome 1B proteinMouse models of USH1C and DFNB18: phenotypic and molecular analyses of two new spontaneous mutations of the Ush1c gene.The very large G-protein-coupled receptor VLGR1: a component of the ankle link complex required for the normal development of auditory hair bundles.Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomesThe Usher 1B protein, MYO7A, is required for normal localization and function of the visual retinoid cycle enzyme, RPE65The role of Rab27a in the regulation of melanosome distribution within retinal pigment epithelial cellsUsher syndrome: Hearing loss, retinal degeneration and associated abnormalities.myosin 7aa(-/-) mutant zebrafish show mild photoreceptor degeneration and reduced electroretinographic responses.Localization of Usher 1 proteins to the photoreceptor calyceal processes, which are absent from mice.Deafness and retinal degeneration in a novel USH1C knock-in mouse modelUsh1c gene expression levels in the ear and eye suggest different roles for Ush1c in neurosensory organs in a new Ush1c knockout mouseMyosin7a deficiency results in reduced retinal activity which is improved by gene therapy.Targeted exon sequencing in Usher syndrome type IEIAV-based retinal gene therapy in the shaker1 mouse model for usher syndrome type 1B: development of UshStat.Moderate light-induced degeneration of rod photoreceptors with delayed transducin translocation in shaker1 mice.Photoreceptors in whirler mice show defective transducin translocation and are susceptible to short-term light/dark changes-induced degeneration.Gene Therapy for the Retinal Degeneration of Usher Syndrome Caused by Mutations in MYO7AThe molecular architecture of ribbon presynaptic terminalsMyosin 6 is required for iris development and normal function of the outer retina.Analysis of subcellular localization of Myo7a, Pcdh15 and Sans in Ush1c knockout mice.Cone degeneration is triggered by the absence of USH1 proteins but prevented by antioxidant treatments.The genetic dissection of Myo7a gene expression in the retinas of BXD mice.
P2860
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P2860
Electroretinographic anomalies in mice with mutations in Myo7a, the gene involved in human Usher syndrome type 1B
description
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
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im März 2001 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2001/03/01)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/03/01)
@nl
наукова стаття, опублікована в березні 2001
@uk
مقالة علمية (نشرت في مارس 2001)
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name
Electroretinographic anomalies ...... n human Usher syndrome type 1B
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Electroretinographic anomalies ...... n human Usher syndrome type 1B
@en
Electroretinographic anomalies ...... n human Usher syndrome type 1B
@nl
type
label
Electroretinographic anomalies ...... n human Usher syndrome type 1B
@ast
Electroretinographic anomalies ...... n human Usher syndrome type 1B
@en
Electroretinographic anomalies ...... n human Usher syndrome type 1B
@nl
prefLabel
Electroretinographic anomalies ...... n human Usher syndrome type 1B
@ast
Electroretinographic anomalies ...... n human Usher syndrome type 1B
@en
Electroretinographic anomalies ...... n human Usher syndrome type 1B
@nl
P1476
Electroretinographic anomalies ...... n human Usher syndrome type 1B
@en
P2093
P304
P407
P577
2001-03-01T00:00:00Z